Zobrazeno 1 - 10
of 79
pro vyhledávání: '"inflammation/fibrosis"'
Autor:
Yu Zhang, Rong Wu, Xi Zhan, Xuan-Yi Wang, Lin-Wei Xiang, Ya-Qian Duan, Yan You, Jian-Bo Zhang, Rui Wu, Yun-Yuan Zhang, Liang Duan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Absent in melanoma 2 (AIM2) inflammasome-dependent pyroptosis and neutrophil extracellular traps (NETs) have been implicated in chronic liver disease (CLD). However, the specific intrahepatic cell type that undergoes AIM2 inflamma
Externí odkaz:
https://doaj.org/article/f12fa08df755413ca610fcac00224466
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 3967-3982 (2024)
Jia Shi,1,2,* Meng-Jiao Shao,3,* Miao Yu,1,2 Bao-Peng Tang1,2 1Cardiac Pacing and Physiological Department, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Xinjiang Key Laboratory
Externí odkaz:
https://doaj.org/article/6fa31193eefa437c9f5a414605b06dfa
Autor:
Elsayed A. Elmorsy, Mahmoud E. Youssef, Mohamed R. Abdel-Hamed, Maha M. Amer, Sahar R. Elghandour, Abdullah S. Alkhamiss, Nahla B. Mohamed, Mostafa M. Khodeir, Hossam A. Elsisi, Thamir Saad Alsaeed, Manal M. Kamal, Abousree T. Ellethy, Basem H. Elesawy, Sameh Saber
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ulcerative colitis (UC) is a debilitating chronic disease marked by persistent inflammation and intestinal fibrosis. Despite the availability of various treatments, many patients fail to achieve long-term remission, underscoring a significant unmet t
Externí odkaz:
https://doaj.org/article/f43b81dbe1f642aabaa4386af9af4885
Autor:
Amir Mohamed Abdelhamid, Sameh Saber, Rabab S. Hamad, Mustafa Ahmed Abdel-Reheim, Abousree T. Ellethy, Maha M. Amer, Mohamed R. Abdel-Hamed, Enas A. Mohamed, Syed Suhail Ahmed, Hossam A. Elsisi, Mostafa M. Khodeir, Abdullah S. Alkhamiss, AlSalloom A. A., Mawahib Ahmed Elawad Abu Elgasim, Zainab H. Almansour, Basem H. Elesawy, Elsayed A. Elmorsy
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionLiver fibrosis is a significant global health burden that lacks effective therapies. It can progress to cirrhosis and hepatocellular carcinoma (HCC). Aberrant hedgehog pathway activation is a key driver of fibrogenesis and cancer, making
Externí odkaz:
https://doaj.org/article/a7d96f1e0f924b6faa4a3c98faf764e0
Autor:
Claudia D. Fuchs, Natalie Sroda, Hubert Scharnagl, Ruchi Gupta, Wesley Minto, Tatjana Stojakovic, John T. Liles, Grant Budas, David Hollenback, Michael Trauner
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100874- (2023)
Background & Aims: The nuclear receptor farnesoid X receptor (FXR) is a key regulator of hepatic bile acid (BA) and lipid metabolism, inflammation and fibrosis. Here, we aimed to explore the potential of cilofexor (GS-9674), a non-steroidal FXR agoni
Externí odkaz:
https://doaj.org/article/98d4075a323d4c7285415bf45d052aaa
Akademický článek
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Publikováno v:
International Journal of Reproductive BioMedicine, Vol 18, Iss 7, Pp 569-580 (2022)
Abstract Background: Chronic heat stress is a risk factor that adversely affects the reproduction system. Inflammation and fibrosis are 2 important response processes to damaged tissues. Objective: This study investigates the association of chronic s
Externí odkaz:
https://doaj.org/article/452cd59430714e84bcdeea2857c892f9
Autor:
Tae Yoon Kim, Jong Min Kim, Hyo Lim Lee, Min Ji Go, Seung Gyum Joo, Ju Hui Kim, Han Su Lee, Won Min Jeong, Dong Yeol Lee, Hyun-Jin Kim, Ho Jin Heo
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1743 (2023)
This study investigated the ameliorating effect of the aqueous extract of Codium fragile on PM2.5-induced pulmonary dysfunction. The major compounds of Codium fragile were identified as palmitic acid, stearic acid, and oleamide using GC/MS2 and hexad
Externí odkaz:
https://doaj.org/article/5b9dd95a4e9c4630bb1a58570d488dc7
Publikováno v:
Medičnì Perspektivi, Vol 25, Iss 4, Pp 59-65 (2020)
The aim of the study was to determine the categories of COPD patients with a predominance of fibrotic or inflammatory processes. The study included 37 stable COPD patients (men – 33 (89.2%), women – 4 (10.8%), mean age – 63.5±1.18 years, the l
Externí odkaz:
https://doaj.org/article/32823ebf6c504a658db117484d4200df
Akademický článek
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