Zobrazeno 1 - 10
of 3 537
pro vyhledávání: '"inflammaging"'
Autor:
Stearns, Stephen C., author, Medzhitov, Ruslan, author
Publikováno v:
Evolutionary Medicine, 2024, ill.
Externí odkaz:
https://doi.org/10.1093/oso/9780192871978.003.0008
Autor:
Anteneh Mehari Tizazu
Publikováno v:
Aging Medicine, Vol 7, Iss 4, Pp 499-509 (2024)
Abstract Aging is a multifaceted process impacting cells, tissues, organs, and organ systems of the body. Like other systems, aging affects both the adaptive and the innate components of the immune system, a phenomenon known as immunosenescence. The
Externí odkaz:
https://doaj.org/article/784428d64222464b91442f5f36443289
Publikováno v:
Clinical Interventions in Aging, Vol Volume 19, Pp 1393-1405 (2024)
Christine K Kim,1 Melisa Z Karslioglu,1 Sharon H Zhao,2 Olivia L Lee1 1Gavin Herbert Eye Institute, University of California, Irvine School of Medicine, Irvine, CA, USA; 2Feinberg School of Medicine, Northwestern University, Chicago, IL, USACorrespon
Externí odkaz:
https://doaj.org/article/3907e7e173c24a50a0b7ebc1f9aec91d
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 711-716 (2024)
TLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens. Polymorphisms in genes involved
Externí odkaz:
https://doaj.org/article/72e52993f1694815a430cd012bf50fac
Autor:
Rachel L. Kidd, Akosua Agyemang-Prempeh, Alan Sanderson, Charlotte Stuart, Sumeet Mahajan, Carl A. Verschuur, Tracey A. Newman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Low-grade chronic inflammation is associated with many age-related conditions. Non-invasive methods to monitor low-grade chronic inflammation may improve the management of older people at risk of poorer outcomes. This longitudinal cohort stu
Externí odkaz:
https://doaj.org/article/a1f1b475dd39425fbe7e4fa29e4559e1
Autor:
Ahmed A. Y. Ragab, Margaret F. Doyle, Jiachen Chen, Yuan Fang, Kathryn L. Lunetta, Joanne M. Murabito
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Global life expectancy is rising, with the 60 + age group projected to hit 2 billion by 2050. Aging impacts the immune system. A notable marker of immune system aging is the presence of Aging-Related Immune Cell Phenotypes (ARIPs)
Externí odkaz:
https://doaj.org/article/c41cb3cf9955436687290af42e544dee
Autor:
Zaoqu Liu, Lulu Zuo, Zhaokai Zhou, Shutong Liu, Yuhao Ba, Anning Zuo, Yuqing Ren, Chuhan Zhang, Yukang Chen, Hongxuan Ma, Yudi Xu, Peng Luo, Quan Cheng, Hui Xu, Yuyuan Zhang, Siyuan Weng, Xinwei Han
Publikováno v:
MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)
Abstract Tumor immunotherapy has significantly transformed the field of oncology over the past decade. An optimal tumor immunotherapy would ideally elicit robust innate and adaptive immune responses within tumor immune microenvironment (TIME). Unfort
Externí odkaz:
https://doaj.org/article/18e265a0687c401c9386493b953e60f4
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundAging can impair the ability of elderly individuals to fight infections and trigger persistent systemic inflammation, a condition known as inflammaging. However, the mechanisms underlying the development of inflammaging remain unknown.Metho
Externí odkaz:
https://doaj.org/article/0a8c4a01ace4467e83bbca86f8c4264d
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
As we age, our immune system’s ability to effectively respond to pathogens declines, a phenomenon known as immunosenescence. This age-related deterioration affects both innate and adaptive immunity, compromising immune function and leading to chron
Externí odkaz:
https://doaj.org/article/9c6e517396de4ad0a9a939a70c0522c5
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Nrf2 is a master transcriptional regulator of a number of genes involved in the adaptive response to oxidative stress. Among the genes upregulated by Nrf2, heme oxygenase-1 (HO-1) has received significant attention, given that the products of HO-1-in
Externí odkaz:
https://doaj.org/article/ef23c82e735d4bb0815bca6480ca004d