Zobrazeno 1 - 10
of 150
pro vyhledávání: '"infiltrating T-lymphocytes"'
Autor:
Hong Guo, Xia Li, Dengxuan Mao, Hong Wang, Liangyin Wei, Ding Qu, Xiaoying Qin, Xiaoqi Li, Yuping Liu, Yan Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract The insufficient abundance and weak activity of tumour-infiltrating lymphocytes (TILs) are two important reasons for the poor efficacy of PD-1 inhibitors in hepatocellular carcinoma (HCC) treatment. The combined administration of tanshinone
Externí odkaz:
https://doaj.org/article/20208845e30440a29984cf1059067259
Autor:
Yangyang Ji, Yu Heng, Xiaoke Zhu, Duo Zhang, Di Tang, Jian Zhou, Hanqing Lin, Jingyu Ma, Xuping Ding, Lei Tao, Liming Lu
Publikováno v:
Translational Oncology, Vol 45, Iss , Pp 101936- (2024)
The infiltration and prognostic significance of tumor-infiltrating plasmacytoid dendritic cells (TI-pDC) have been elucidated in various human solid cancers. However, the infiltrating patterns and functional importance of TI-pDC in laryngeal squamous
Externí odkaz:
https://doaj.org/article/96bb1643cb624f7f96975702d3afb6e0
Autor:
Chih-Chia Chang, Chia-Bin Chang, Chiung-Ju Chen, Chun-Liang Tung, Chi-Feng Hung, Wei-Hong Lai, Cheng-Huang Shen, Chang-Yu Tsai, Ya-Yan Lai, Ming-Yang Lee, Shu-Fen Wu, Pi-Che Chen
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 2155-2165 (2024)
An increased neutrophil-to-lymphocyte ratio (NLR) is a poor prognostic biomarker in various types of cancer, because it reflects the inhibition of lymphocytes in the circulation and tumors. In urologic cancers, upper tract urothelial carcinoma (UTUC)
Externí odkaz:
https://doaj.org/article/887a21251c81426cadd25f3c1a89f0ab
Autor:
Erkki-Ville Wirta, Säde Szeto, Hanna Koppatz, Arno Nordin, Heikki Mäkisalo, Johanna Arola, Jukka Sirén, Maarit Ahtiainen, Jan Böhm, Jukka-Pekka Mecklin, Ville Sallinen, Toni T. Seppälä
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundAntitumoral immune response has a crucial role in constraining cancer. However, previous studies on cholangiocarcinoma (CCA), a rare and aggressive cancer, have reported contradictory findings on the prognostic impact of tumor-infiltrating
Externí odkaz:
https://doaj.org/article/6ba3ee274f80408593b61e0eb61c28df
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 6, Pp 1310-1327 (2023)
Cholangiocarcinoma (CCA) is a highly aggressive type of adenocarcinoma distinguished by its invasiveness. Depending on specific anatomical positioning within the biliary tree, CCA can be categorized into intrahepatic CCA (ICCA), perihilar CCA (pCCA)
Externí odkaz:
https://doaj.org/article/6eab91bcb1324c5683fe7cd3eb2a5624
Autor:
Peng Ouyang, Lijuan Wang, Jianlong Wu, Yao Tian, Caiyun Chen, Dengsheng Li, Zengxi Yao, Ruichang Chen, Guoan Xiang, Jin Gong, Zhen Bao
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immune Checkpoint Inhibitors (ICIs) therapy has advanced significantly in treating malignant tumors, though most ‘cold’ tumors show no response. This resistance mainly arises from the varied immune evasion mechanisms. Hence, understanding the tra
Externí odkaz:
https://doaj.org/article/edc5a82250eb465081c935834c071ec5
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer that represents 15–20% of breast tumors and is more prevalent in young pre-menopausal women. It is the subtype of breast cancers with the highest metastatic po
Externí odkaz:
https://doaj.org/article/b55a31c22b41443f9aaa99fa9fbc931e
Autor:
Runzhi Huang, Dan Huang, Siqiao Wang, Shuyuan Xian, Yifan Liu, Minghao Jin, Xinkun Zhang, Shaofeng Chen, Xi Yue, Wei Zhang, Jianyu Lu, Huizhen Liu, Zongqiang Huang, Hao Zhang, Huabin Yin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: The molecular mechanisms of EWS-FLI-mediating target genes and downstream pathways may provide a new way in the targeted therapy of Ewing sarcoma. Meanwhile, enhancers transcript non-coding RNAs, known as enhancer RNAs (eRNAs), which may
Externí odkaz:
https://doaj.org/article/85057ba576434148b2b06c35e97a70c2