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pro vyhledávání: '"inference of fitness landscapes"'
A common challenge arising from the observation of an evolutionary system over time is to infer the magnitude of selection acting upon a specific genetic variant, or variants, within the population. The inference of selection may be confounded by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b5f679ee3104cf73a97d9bb198c6df
https://www.repository.cam.ac.uk/handle/1810/275812
https://www.repository.cam.ac.uk/handle/1810/275812
Publikováno v:
Genetics
A broad range of approaches have considered the challenge of inferring selection from time-resolved genome sequence data. Models describing deterministic changes in allele or haplotype frequency have been highlighted as providing accurate and computa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9011a41e89ede196ceb1c50228ac921
https://pubmed.ncbi.nlm.nih.gov/29500183
https://pubmed.ncbi.nlm.nih.gov/29500183
Akademický článek
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Publikováno v:
Bioinformatics; Jul2019, Vol. 35 Issue 14, pi398-i407, 10p
Publikováno v:
Bioinformatics
SummaryIntra-tumor heterogeneity is one of the major factors influencing cancer progression and treatment outcome. However, evolutionary dynamics of cancer clone populations remain poorly understood. Quantification of clonal selection and inference o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3f0e507e41d00832a15b6ca883daa1
https://doi.org/10.1093/bioinformatics/btz392
https://doi.org/10.1093/bioinformatics/btz392
Autor:
Nosil, Patrik, Villoutreix, Romain, de Carvalho, Clarissa F., Feder, Jeffrey L., Parchman, Thomas L., Gompert, Zach
Publikováno v:
Nature Ecology & Evolution; 2020, Vol. 4 Issue 12, p1673-1684, 12p
Autor:
Lähnemann, David, Köster, Johannes, Szczurek, Ewa, McCarthy, Davis J., Hicks, Stephanie C., Robinson, Mark D., Vallejos, Catalina A., Campbell, Kieran R., Beerenwinkel, Niko, Mahfouz, Ahmed, Pinello, Luca, Skums, Pavel, Stamatakis, Alexandros, Attolini, Camille Stephan-Otto, Aparicio, Samuel, Baaijens, Jasmijn, Balvert, Marleen, Barbanson, Buys de, Cappuccio, Antonio, Corleone, Giacomo
Publikováno v:
Genome Biology; 2/7/2020, Vol. 21 Issue 1, p1-35, 35p
Publikováno v:
Bioinformatics; Jul2019, Vol. 35 Issue 14, pi389-i397, 9p
Autor:
Louie, Raymond H. Y., Kaczorowski, Kevin J., Barton, John P., Chakraborty, Arup K., Mckay, Matthew R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 1/23/2018, Vol. 115 Issue 4, pE564-E573, 10p
Autor:
Seifert, David, Beerenwinkel, Niko
Publikováno v:
Quasispecies: From Theory to Experimental Systems; 2016, p181-200, 20p