Zobrazeno 1 - 10
of 129
pro vyhledávání: '"inducible Cre"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Murine models of long-bone fracture, stress fracture, and cortical defect are used to discern the cellular and molecular mediators of intramembranous and endochondral bone healing. Previous work has shown that Osterix (Osx+) and Dentin Matrix Protein
Externí odkaz:
https://doaj.org/article/6e4b7e79b41e41079e73041107f7727b
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-8 (2020)
Abstract Genetically engineered mouse models through gene deletion are useful tools for analyzing gene function. To delete a gene in a certain tissue temporally, tissue-specific and tamoxifen-inducible Cre transgenic mice are generally used. Here, we
Externí odkaz:
https://doaj.org/article/1e66b568bedf4d9ba75f3d4d331e04b3
Autor:
Naushin L. Hindul, Amarjot Jhita, Daiana G. Oprea, Tasnim Alamgir Hussain, Oksana Gonchar, Miguel Angel Muro Campillo, Laura O'Regan, Masato T. Kanemaki, Andrew M. Fry, Kouji Hirota, Kayoko Tanaka
Publikováno v:
Biology Open, Vol 11, Iss 2 (2022)
The human retinal pigment epithelial RPE-1 cell line immortalized with hTERT retains a stable karyotype with a modal chromosome number of 46 and has been widely used to study physiological events in human cell culture systems. To facilitate inducible
Externí odkaz:
https://doaj.org/article/50b84e4115784de1b13ec0fe54f7eb8a
Akademický článek
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Akademický článek
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Autor:
Julia A. Wagner, Pamela Wong, Timothy Schappe, Melissa M. Berrien-Elliott, Celia Cubitt, Natalia Jaeger, Madeline Lee, Cassie R. Keppel, Nancy D. Marin, Jennifer A. Foltz, Lynne Marsala, Carly C. Neal, Ryan P. Sullivan, Stephanie E. Schneider, Molly P. Keppel, Nermina Saucier, Megan A. Cooper, Todd A. Fehniger
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: Natural killer (NK) cells are cytotoxic innate lymphoid cells (ILCs) that mediate antiviral and antitumor responses and require the transcriptional regulator Eomesodermin (Eomes) for early development. However, the role of Eomes and its mole
Externí odkaz:
https://doaj.org/article/eb92f6f224504cbebe7d3cfdfd2d8b82
Publikováno v:
Cells, Vol 11, Iss 1, p 121 (2021)
Fibroblast growth factor 1 (FGF1) regulates many biological and physiological processes. In mice, Fgf1 gene contains at least three upstream promoters and are alternatively spliced to the first protein coding exon, giving rise to different Fgf1 mRNA
Externí odkaz:
https://doaj.org/article/c81369ae0dd747e59e184df3bff21947
Autor:
Marion Benazra, Marie-José Lecomte, Claire Colace, Andreas Müller, Cécile Machado, Severine Pechberty, Emilie Bricout-Neveu, Maud Grenier-Godard, Michele Solimena, Raphaël Scharfmann, Paul Czernichow, Philippe Ravassard
Publikováno v:
Molecular Metabolism, Vol 4, Iss 12, Pp 916-925 (2015)
Objectives: Access to immortalized human pancreatic beta cell lines that are phenotypically close to genuine adult beta cells, represent a major tool to better understand human beta cell physiology and develop new therapeutics for Diabetes. Here we d
Externí odkaz:
https://doaj.org/article/c99264b7f4324fab94afdcac5d1b45dc
Publikováno v:
Cells, Vol 11, Iss 121, p 121 (2022)
Cells
Cells; Volume 11; Issue 1; Pages: 121
Cells
Cells; Volume 11; Issue 1; Pages: 121
Fibroblast growth factor 1 (FGF1) regulates many biological and physiological processes. In mice, Fgf1 gene contains at least three upstream promoters and are alternatively spliced to the first protein coding exon, giving rise to different Fgf1 mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d56e01afd0072030b804e238fead47a
https://www.mdpi.com/2073-4409/11/1/121
https://www.mdpi.com/2073-4409/11/1/121
Autor:
Emilio P. Mottillo, Priya Balasubramanian, Yun-Hee Lee, Changren Weng, Erin E. Kershaw, James G. Granneman
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2276-2286 (2014)
Chronic activation of β3-adrenergic receptors (β3-ARs) expands the catabolic activity of both brown and white adipose tissue by engaging uncoupling protein 1 (UCP1)-dependent and UCP1-independent processes. The present work examined de novo lipogen
Externí odkaz:
https://doaj.org/article/1eb9f31d5ec94619a83cea483bd80d27