Zobrazeno 1 - 10
of 94
pro vyhledávání: '"induced neuronal cells"'
Autor:
Noriaki Sagata, Shin‐ichi Kano, Masahiro Ohgidani, Shogo Inamine, Yasunari Sakai, Hiroki Kato, Keiji Masuda, Takeshi Nakahara, Makiko Nakahara‐Kido, Shouichi Ohga, Masutaka Furue, Akira Sawa, Shigenobu Kanba, Takahiro A. Kato
Publikováno v:
Neuropsychopharmacology Reports, Vol 40, Iss 4, Pp 396-400 (2020)
Abstract Aim Neurofibromatosis type 1 (NF1) is a multifaceted disease, and frequently comorbid with neurodevelopmental disorders such as autism spectrum disorder (ASD) and learning disorder. Dysfunction of adenylyl cyclase (AC) is one of the candidat
Externí odkaz:
https://doaj.org/article/ee59a769ea2f4ccfbc0fe75e7c8893c3
Autor:
Tanabe, Koji, Ang, Cheen Euong, Chanda, Soham, Olmos, Victor Hipolito, Haag, Daniel, Levinson, Douglas F., Südhof, Thomas C., Wernig, Marius
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun . 115(25), 6470-6475.
Externí odkaz:
https://www.jstor.org/stable/26510484
Akademický článek
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Autor:
Orly L. Wapinski, Qian Yi Lee, Albert C. Chen, Rui Li, M. Ryan Corces, Cheen Euong Ang, Barbara Treutlein, Chaomei Xiang, Valérie Baubet, Fabian Patrik Suchy, Venkat Sankar, Sopheak Sim, Stephen R. Quake, Nadia Dahmane, Marius Wernig, Howard Y. Chang
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3236-3247 (2017)
How transcription factors (TFs) reprogram one cell lineage to another remains unclear. Here, we define chromatin accessibility changes induced by the proneural TF Ascl1 throughout conversion of fibroblasts into induced neuronal (iN) cells. Thousands
Externí odkaz:
https://doaj.org/article/f94ed8fb92644ec5875519ed63f8a4eb
Autor:
Ahlenius, Henrik, Chanda, Soham, Webb, Ashley E., Yousif, Issa, Karmazin, Jesse, Prusiner, Stanley B., Brunet, Anne, Südhof, Thomas C., Wernig, Marius
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Jul . 113(30), 8514-8519.
Externí odkaz:
https://www.jstor.org/stable/26470965
Autor:
Cheen Euong Ang, Qing Ma, Orly L Wapinski, ShengHua Fan, Ryan A Flynn, Qian Yi Lee, Bradley Coe, Masahiro Onoguchi, Victor Hipolito Olmos, Brian T Do, Lynn Dukes-Rimsky, Jin Xu, Koji Tanabe, LiangJiang Wang, Ulrich Elling, Josef M Penninger, Yang Zhao, Kun Qu, Evan E Eichler, Anand Srivastava, Marius Wernig, Howard Y Chang
Publikováno v:
eLife, Vol 8 (2019)
Long noncoding RNAs (lncRNAs) have been shown to act as important cell biological regulators including cell fate decisions but are often ignored in human genetics. Combining differential lncRNA expression during neuronal lineage induction with copy n
Externí odkaz:
https://doaj.org/article/60e20b5e18eb47a88838b2322084fb91
Autor:
Shogo Inamine, Shin Ichi Kano, Masutaka Furue, Masahiro Ohgidani, Makiko Nakahara-Kido, Yasunari Sakai, Noriaki Sagata, Takeshi Nakahara, Takahiro A. Kato, Shouichi Ohga, Shigenobu Kanba, Akira Sawa, Keiji Masuda, Hiroki Kato
Publikováno v:
Neuropsychopharmacology Reports
Aim Neurofibromatosis type 1 (NF1) is a multifaceted disease, and frequently comorbid with neurodevelopmental disorders such as autism spectrum disorder (ASD) and learning disorder. Dysfunction of adenylyl cyclase (AC) is one of the candidate pathway
Autor:
Barbagiovanni, Giulia, Germain, Pierre Luc, Zech, Michael, Atashpaz, Sina, Lo Riso, Pietro, D'Antonio-Chronowska, Agnieszka, Tenderini, Erika, Caiazzo, Massimiliano, Boesch, Sylvia, Jech, Robert, Haslinger, Bernhard, Broccoli, Vania, Stewart, Adrian Francis, Winkelmann, Juliane, Testa, Giuseppe, Afd Pharmaceutics, Pharmaceutics
Publikováno v:
Cell Reports, 25(4), 988. Elsevier Saunders
Cell Reports, 25 (4)
Cell Reports, Vol 25, Iss 4, Pp 988-1001 (2018)
Cell Reports, 25 (4)
Cell Reports, Vol 25, Iss 4, Pp 988-1001 (2018)
Transdifferentiation of fibroblasts into induced neuronal cells (iNs) by the neuron-specific transcription factors Brn2, Myt1l, and Ascl1 is a paradigmatic example of inter-lineage conversion across epigenetically distant cells. Despite tremendous pr
Autor:
Mohammed Al-Hawwas, Hong Liao, Donghui Liu, Larisa Bobrovskaya, Xin-Fu Zhou, Grigori Y. Rychkov, Nimshitha Pavathuparambil Abdul Manaph, Fiona H. Zhou
Neural cell transplantation is an effective way for treatment of neurological diseases. However, the absence of transplantable human neurons remains a barrier for clinical therapies. Human urine-derived cells, namely renal cells and urine stem cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59dc12d269b1cecf3749c21727545274
https://hdl.handle.net/11541.2/141631
https://hdl.handle.net/11541.2/141631
Autor:
Toru Yamashita, Koji Abe
Publikováno v:
Neurologia medico-chirurgica
The discovery of induced pluripotent stem (iPS) cells opened the gate for reprogramming technology with which we can change the cell fate through overexpression of master transcriptional factors. Now we can prepare various kinds of neuronal cells dir