Zobrazeno 1 - 10
of 101
pro vyhledávání: '"induced cardiomyocytes"'
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103331- (2024)
We generated a human induced pluripotent stem cell (hiPSC) line from erythroid progenitor cells (EPCs) of a 20-year-old female healthy donor using Sendai virus vector encoding Yamanaka factors OCT3/4, SOX2, c-MYC, and KLF4. The established hiPSCs sho
Externí odkaz:
https://doaj.org/article/b79bf2bd2af24af49bd246b71067d53b
Autor:
Anna Kabłak-Ziembicka, Rafał Badacz, Michał Okarski, Magdalena Wawak, Tadeusz Przewłocki, Jakub Podolec
Publikováno v:
Archives of Medical Science, Vol 19, Iss 5, Pp 1360-1381 (2023)
MicroRNAs are small non-coding post-translational biomolecules which, when expressed, modify their target genes. It is estimated that microRNAs regulate production of approximately 60% of all human proteins and enzymes that are responsible for major
Externí odkaz:
https://doaj.org/article/4b1c253a50e0482f857fccf56989b7a8
Autor:
Hiroyuki Yamakawa, Masaki Ieda
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-10 (2021)
Abstract Japan faces an increasing incidence of heart disease, owing to a shift towards a westernized lifestyle and an aging demographic. In cases where conventional interventions are not appropriate, regenerative medicine offers a promising therapeu
Externí odkaz:
https://doaj.org/article/9351bf92925c46a4a4a16533519f963d
Publikováno v:
International Journal of Nanomedicine, Vol Volume 16, Pp 3741-3754 (2021)
Lei Yang, Song Xue, Mingjun Du, Feng Lian Department of Cardiovascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People’s Republic of ChinaCorrespondence: Feng Lian Email dr.lianfeng@hotmail.comIn
Externí odkaz:
https://doaj.org/article/15d9455fb7054bdb880c59c7bc7c4d94
Publikováno v:
Cells, Vol 12, Iss 8, p 1166 (2023)
Cardiac diseases are the foremost cause of morbidity and mortality worldwide. The heart has limited regenerative potential; therefore, lost cardiac tissue cannot be replenished after cardiac injury. Conventional therapies are unable to restore functi
Externí odkaz:
https://doaj.org/article/3a190134f656450c9a977013290debf6
Akademický článek
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Publikováno v:
Advanced Science, Vol 7, Iss 7, Pp n/a-n/a (2020)
Abstract Using direct conversion technology, normal adult somatic cells can be routinely switched from their original cell type into specific differentiated cell types by inducing the expression of differentiation‐related transcription factors. In
Externí odkaz:
https://doaj.org/article/fab61ccd57244d2e87aec8bd964ff912
Autor:
Camilla Paoletti, Elena Marcello, Maria Luna Melis, Carla Divieto, Daria Nurzynska, Valeria Chiono
Publikováno v:
Cells, Vol 11, Iss 5, p 800 (2022)
The restoration of cardiac functionality after myocardial infarction represents a major clinical challenge. Recently, we found that transient transfection with microRNA combination (miRcombo: miR-1, miR-133, miR-208 and 499) is able to trigger direct
Externí odkaz:
https://doaj.org/article/554a3b73439f4063ba389768704e4bec
Autor:
Kimberly Sauls, Todd M. Greco, Li Wang, Meng Zou, Michelle Villasmil, Li Qian, Ileana M. Cristea, Frank L. Conlon
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1913-1922 (2018)
Summary: Direct reprogramming of fibroblasts into cardiomyocyte-like cells (iCM) holds great potential for heart regeneration and disease modeling and may lead to future therapeutic applications. Currently, application of this technology is limited b
Externí odkaz:
https://doaj.org/article/bac189e50a6e49b39170ff11cfe6e043
Akademický článek
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