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In silico Study of the Pharmacologic Properties and Cytotoxicity Pathways in Cancer Cells of Various Indolylquinone Analogues of Perezone

Autor: René Escobedo-González, Claudia Lucia Vargas-Requena, Edgar Moyers-Montoya, Juan Manuel Aceves-Hernández, María Inés Nicolás-Vázquez, René Miranda-Ruvalcaba

Publikováno v: Molecules, Vol 22, Iss 7, p 1060 (2017)

Several indolylquinone analogues of perezone, a natural sesquiterpene quinone, were characterized in this work by theoretical methods. In addition, some physicochemical, toxicological and metabolic properties were predicted using bioinformatics softw

Externí odkaz: https://doaj.org/article/5c95c73714d5468e80bbfa867c0869df

An investigation of nucleophilic substitution reactions of 2,3-dichloro-1,4-naphthoquinone with various nucleophilic reagents

Autor: Sibel Sahinler Ayla, Hakan Bahar, Cemil Ibis, Ahmed Hassen Shntaif

Publikováno v: Journal of the Serbian Chemical Society, Vol 80, Iss 6, Pp 731-738 (2015)

Novel N- , N,S- and N,O- substituted naphthoquinone compounds were prepared by the reactions of 2,3-dichloro-1,4-naphthoquinone (1) and the corresponding nucleophiles in the presence of chloroform and triethylamine or ethanol solution of Na2CO3. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9976cc7edf0b73d2114907b15b56982d
https://doi.org/10.2298/jsc141124021i

Synthesis of Indolylquinones as a Potential Therapy for Diabetes and as Candidates for Neuroprotection

Autor: Massoud, Theresa C.

Publikováno v: Massoud, Theresa C.(2010). Synthesis of Indolylquinones as a Potential Therapy for Diabetes and as Candidates for Neuroprotection. UC Riverside: Chemistry. Retrieved from: http://www.escholarship.org/uc/item/1c12s3rx

Asterriquinones display a wide range of biological activity. From antiretroviral and antitumor activity, to anti-diabetes properties and neuroprotection, asterriquinones and their analogs have quickly become a popular target in pharmaceutical researc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::51fbc6b35f3e9ba4464ff3614f8ece13
http://n2t.net/ark:/13030/m5w95b0k