Zobrazeno 1 - 10
of 324
pro vyhledávání: '"individualized dosing"'
Autor:
Anjali T. Owens, Milind Desai, Matthew T. Wheeler, Anna Rodonski, Samira Merali, Amy J. Sehnert, Sara Saberi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Mavacamten is the first and only cardiac myosin inhibitor approved in 5 continents for the treatment of adults with symptomatic New York Heart Association class II and III obstructive hypertrophic cardiomyopathy. An evidence‐based rationale was use
Externí odkaz:
https://doaj.org/article/a01f4f2d76b64c1f85ec6c340522d7c9
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1122 (2024)
Remimazolam, widely used for procedural sedation and general anesthesia, is a new ultra short-acting benzodiazepine for intravenous sedation and anesthesia. We aim to characterize the pharmacokinetics/pharmacodynamics (PK/PD) of remimazolam and its m
Externí odkaz:
https://doaj.org/article/67c03e030f81494cb5a2b0528e1b8162
Autor:
Nuo Xu, Yufei Shi, Yixue Wang, Wenyao Mak, Wenyu Yang, Kar Weng Ng, Yue Wu, Zhijia Tang, Qingfeng He, Gangfeng Yan, Xiaoqiang Xiang, Xiao Zhu
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 819 (2024)
Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections. Pharmacokinetic (PK) varia
Externí odkaz:
https://doaj.org/article/bf6ebeaa7c4e4fc68a5843de4c6596cb
Autor:
Manuel Fernández Sánchez, Per Larsson, Marcos Ferrando Serrano, Ernesto Bosch, Juan Antonio García Velasco, Esther Santamaría López, Bernadette Mannaerts
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Purpose To explore the efficacy and safety of individualized follitropin delta dosing, based on serum anti-Müllerian hormone (AMH) concentration and bodyweight, in a long gonadotropin-releasing hormone (GnRH) agonist protocol. Methods Clini
Externí odkaz:
https://doaj.org/article/ec91af6547b141a88d00740139605261
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Due to the heterogeneity of critically ill patients, the pharmacokinetics of tigecycline are unclear, and the optimal dosing strategy is controversial.Methods: A single-center prospective clinical study that included critically ill patien
Externí odkaz:
https://doaj.org/article/b07dddbaa27e4674aa2b5f922dfbd410
Autor:
Lin Zhao, Jiamei Chen, Bai Bai, Guili Song, Jingwen Zhang, Han Yu, Shiwei Huang, Zhang Wang, Guanghua Lu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Topical drug delivery is widely used in various diseases because of the advantages of not passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first-pass effect, and reaching the lesion directly to reduce unnec
Externí odkaz:
https://doaj.org/article/e752b1ea6aeb499299afd906e9a9b4ac
Autor:
Anne E. Martini, Stephanie Beall, G David Ball, Brooke Hayward, Thomas D’Hooghe, Mary C. Mahony, Fabricio Collares, Allison B. Catherino
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionFine-tuning of injectable gonadotropin doses during ovulation induction (OI) or ovarian stimulation (OS) treatment cycles with the aim of using doses low enough to minimize the risk of excessive ovarian response while maintaining optimal
Externí odkaz:
https://doaj.org/article/f28f0ec0209743e79c730b425d024a59
Autor:
Rui Yang, Yunshan Zhang, Xiaoyan Liang, Xueru Song, Zhaolian Wei, Jianqiao Liu, Yezhou Yang, Jichun Tan, Qingxue Zhang, Yingpu Sun, Wei Wang, Weiping Qian, Lei Jin, Shuyu Wang, Yang Xu, Jing Yang, Marie Goethberg, Bernadette Mannaerts, Wen Wu, Zugeng Zheng, Jie Qiao
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background To compare the efficacy and safety of follitropin delta in its individualized fixed-dose regimen with follitropin alfa in a conventional adjustable dosing regimen in Chinese women. Methods This was a subgroup analysis of the rando
Externí odkaz:
https://doaj.org/article/542c8d59ec0c4d1091523e71d72961fb
Autor:
Johannes T. Reckweg, Cees J. van Leeuwen, Cécile Henquet, Therese van Amelsvoort, Eef L. Theunissen, Natasha L. Mason, Riccardo Paci, Theis H. Terwey, Johannes G. Ramaekers
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundTreatment-resistant depression (TRD) is a substantial public health burden, but current treatments have limited effectiveness. The aim was to investigate the safety and potential antidepressant effects of the serotonergic psychedelic drug 5
Externí odkaz:
https://doaj.org/article/5cf36a66e67747d999cfcbb1b9cc5fe1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.