Zobrazeno 1 - 10
of 105
pro vyhledávání: '"in vivo two-photon imaging"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The perivascular space (PVS) surrounds cerebral blood vessels and plays an important role in clearing waste products from the brain. Their anatomy and function have been described for arteries, but PVS around veins remain poorly characterize
Externí odkaz:
https://doaj.org/article/e6f9f844e8fb4e1192f6bce527ad4a5d
Akademický článek
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Enriched Environment Prevents Surgery-Induced Persistent Neural Inhibition and Cognitive Dysfunction
Autor:
Shana Yang, Song Zhang, Wenting Tang, Shunchang Fang, Hongyang Zhang, Jieyan Zheng, Xia Liu, Ying Zhang, Liang Zhao, Lianyan Huang, Boxing Li
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Perioperative neurocognitive disorders (PND) encompass short-term delirium and long-term cognitive dysfunction. Aging increases the susceptibility to PND, yet the neural mechanism is not known. In this study, we monitored the dynamic changes of neuro
Externí odkaz:
https://doaj.org/article/114d948c2fcf4686b7b8c5a6b5877c70
Autor:
Monique S Mendes, Linh Le, Jason Atlas, Zachary Brehm, Antonio Ladron-de-Guevara, Evelyn Matei, Cassandra Lamantia, Matthew N McCall, Ania K Majewska
Publikováno v:
eLife, Vol 10 (2021)
Microglia are the brain’s resident immune cells with a tremendous capacity to autonomously self-renew. Because microglial self-renewal has largely been studied using static tools, its mechanisms and kinetics are not well understood. Using chronic i
Externí odkaz:
https://doaj.org/article/b7cc595d4ea147a2874a3c324e554f7d
Autor:
Aurélie Soubéran, Sophie Brustlein, Caroline Gouarné, Lionel Chasson, Aurélie Tchoghandjian, Marie Malissen, Geneviève Rougon
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Targeting angiogenesis has been and continues to be an attractive therapeutic modality in glioblastoma (GBM) patients. However, GBM rapidly becomes refractory to anti-VEGF therapies. Myeloid cell infiltration is an important deter
Externí odkaz:
https://doaj.org/article/ff8afad4a717423d93128255f4e3946d
Autor:
Axel von Streitberg, Sarah Jäkel, Jaime Eugenin von Bernhardi, Christoph Straube, Felix Buggenthin, Carsten Marr, Leda Dimou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In the adult brain, NG2-glia represent a cell population that responds to injury. To further investigate if, how and why NG2-glia are recruited to the injury site, we analyzed in detail the long-term reaction of NG2-glia after a lesion by time-lapse
Externí odkaz:
https://doaj.org/article/dbc1239737ca45b99dd045a1f2a0dca6
Akademický článek
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Publikováno v:
BioData Mining, Vol 10, Iss 1, Pp 1-23 (2017)
Abstract Background In the nervous system, the neurons communicate through synapses. The size, morphology, and connectivity of these synapses are significant in determining the functional properties of the neural network. Therefore, they have always
Externí odkaz:
https://doaj.org/article/6f5ebf075a004776acc9f4996e5ed9c3
Autor:
Elma S. Frias, Mahmood S. Hoseini, Karen Krukowski, Maria Serena Paladini, Katherine Grue, Gonzalo Ureta, Kira D.A. Rienecker, Peter Walter, Michael P. Stryker, Susanna Rosi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 42
Traumatic brain injury (TBI) is a leading cause of long-term neurological disability in the world and the strongest environmental risk factor for the development of dementia. Even mild TBI (resulting from concussive injuries) is associated with a >2-