Zobrazeno 1 - 10
of 8 218
pro vyhledávání: '"in vivo imaging"'
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Microglia are highly dynamic cells that play a critical role in tissue homeostasis through the surveillance of brain parenchyma and response to cues associated with damage. Aging and APOE4 genotype are the strongest risk factors for Alzheime
Externí odkaz:
https://doaj.org/article/7936248805824daca77f40ec975cc4d4
Autor:
Zilin Wang, Kunsha Chen, Xiaodong Wu, Pengchang Zheng, Ao Li, Yongxin Guo, Xingzheng Gu, Guihua Xiao, Hao Xie, ChaoWei Zhuang, Jiangbei Cao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116751- (2024)
Anesthesia inhibits neural activity in the brain, causing patients to lose consciousness and sensation during the surgery. Layers 2/3 of the cortex are important structures for the integration of information and consciousness, which are closely relat
Externí odkaz:
https://doaj.org/article/ff79a1988092423d8c0fe980e00496b6
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Preclinical in vivo cancer models are essential tools for investigating tumor progression and response to treatment prior to clinical trials. Although treatment modalities are regularly assessed in mice upon tumor growth in vivo,
Externí odkaz:
https://doaj.org/article/5527119175424e31af69883de21c6e6b
Preparation, Characterization, and Anti-Lung Cancer Activity of Tetrandrine-Loaded Stealth Liposomes
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 787-803 (2024)
Zhengyu Fang,1,* Peihong Lin,1,* Rui Gao,1,* Wenjing Yang,1 Aizhen Zhou,2 Wenying Yu1,3 1School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, People’s Republic of China; 2Department of Traditional Chinese Medicine, Zhejiang P
Externí odkaz:
https://doaj.org/article/6c7bd421e48f42a3810c38e730902a2c
Autor:
Chenshuang Zhang, Bin Yu, Fangrui Lin, Soham Samanta, Huanhuan Yu, Wei Zhang, Yingying Jing, Chunfeng Shang, Danying Lin, Ke Si, Wei Gong, Junle Qu
Publikováno v:
PhotoniX, Vol 4, Iss 1, Pp 1-15 (2023)
Abstract Visualization of axons and dendritic spines is crucial in neuroscience research. However, traditional microscopy is limited by diffraction-limited resolution and shallow imaging depth, making it difficult to study neuronal dynamics. Two-phot
Externí odkaz:
https://doaj.org/article/6bb3b4b9da4d4a8891c541b1d76fe84d
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107314- (2024)
The efficacy of PD-1 therapy in non-small cell lung cancer (NSCLC) patients remains unsatisfactory. Activating the STING pathway is a promising strategy to improve PD-1 inhibitor efficacy. Here, we found tetrandrine (TET), an anti-tumor compound extr
Externí odkaz:
https://doaj.org/article/ddff3eec7fad4f0297bb02db9cf45b17
Autor:
Naoki Nakagawa, Takuji Iwasato
Publikováno v:
Frontiers in Neural Circuits, Vol 18 (2024)
For neural circuit construction in the brain, coarse neuronal connections are assembled prenatally following genetic programs, being reorganized postnatally by activity-dependent mechanisms to implement area-specific computational functions. Activity
Externí odkaz:
https://doaj.org/article/d1b01417c5634475951bc5685c2231ec
Autor:
Raluca-Andrada Munteanu, Adrian Bogdan Tigu, Richard Feder, Andra-Sorina Tatar, Diana Gulei, Ciprian Tomuleasa, Sanda Boca
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Acute myeloid leukemia (AML) is a malignancy in the myeloid lineage that is characterized by symptoms like fatigue, bleeding, infections, or anemia, and it can be fatal if untreated. In AML, mutations in tyrosine kinases (TKs) lead to enhanced tumor
Externí odkaz:
https://doaj.org/article/82cc1fd4396f4137963da2578167bf4e
Publikováno v:
Photonics, Vol 11, Iss 7, p 585 (2024)
Using two independent speckle imaging systems based on the recently published LSOCI method operating in contact mode on the skin, we assess the reproducibility of in vivo measurements and conduct an inter-instrument comparison. To this aim, we propos
Externí odkaz:
https://doaj.org/article/45238a1d7dac4c0b96aba83a390b2805