Zobrazeno 1 - 10
of 134
pro vyhledávání: '"in vitro kinase assay"'
Autor:
Zehan Hu, Devanarayanan Siva Sankar, Bich Vu, Alexandre Leytens, Christine Vionnet, Wenxian Wu, Michael Stumpe, Esther Martínez-Martínez, Björn Stork, Jörn Dengjel
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109762- (2021)
Summary: The evolutionarily conserved ULK1 kinase complex acts as gatekeeper of canonical autophagy and regulates induction of autophagosome biogenesis. To better understand control of ULK1 and analyze whether ULK1 has broader functions that are also
Externí odkaz:
https://doaj.org/article/faaa8cfccbad479e94050be695b0f084
Autor:
Philipp Mertins, Dariusz Przybylski, Nir Yosef, Jana Qiao, Karl Clauser, Raktima Raychowdhury, Thomas M. Eisenhaure, Tanja Maritzen, Volker Haucke, Takashi Satoh, Shizuo Akira, Steven A. Carr, Aviv Regev, Nir Hacohen, Nicolas Chevrier
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2853-2866 (2017)
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical and genetic framework to dissect
Externí odkaz:
https://doaj.org/article/78b5c7901c5847ab990bbd7395c9f727
Autor:
Esther Martínez-Martínez, Christine Vionnet, Wenxian Wu, Alexandre Leytens, Zehan Hu, Michael Stumpe, Jörn Dengjel, Björn Stork, Bich Vu, Devanarayanan Siva Sankar
Publikováno v:
Cell Reports, Vol 36, Iss 13, Pp 109762-(2021)
Summary: The evolutionarily conserved ULK1 kinase complex acts as gatekeeper of canonical autophagy and regulates induction of autophagosome biogenesis. To better understand control of ULK1 and analyze whether ULK1 has broader functions that are also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4176c67881f37e0f5e9a4c42e2746d5
https://pubmed.ncbi.nlm.nih.gov/34592149
https://pubmed.ncbi.nlm.nih.gov/34592149
Autor:
Goetz Hensel, Weiß L, Tina Reiner, Gaelings L, Julia Mergner, Manfred Gahrtz, Bernhard Kuster, Stefan Engelhardt, Attila Fehér, Jochen Kumlehn, Ralph Hückelhoven
Publikováno v:
PLOS ONE, 17(3):e0258924
Small RHO-type G-proteins act as signaling hubs and master regulators of polarity in eukaryotic cells. Their activity is tightly controlled, as defective RHO signaling leads to aberrant growth and developmental defects. Two major processes regulate G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba87f9871601b6dd9f67812a97d9eb37
https://doi.org/10.1371/journal.pone.0258924
https://doi.org/10.1371/journal.pone.0258924
Akademický článek
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Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008561 (2020)
PLoS Genetics
PLoS Genetics
Intraflagellar transport (IFT) is required for ciliary assembly and maintenance. While disruption of IFT may trigger ciliary disassembly, we show here that IFT mediated transport of a CDK-like kinase ensures proper ciliary disassembly. Mutations in f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cbdff5871700ad5b58d17795b87f0c
https://doaj.org/article/93e7623cf5c24eb69a10eb151a576d76
https://doaj.org/article/93e7623cf5c24eb69a10eb151a576d76
Autor:
Timothy P. Devarenne, In-Cheol Yeo
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234011 (2020)
PLoS ONE
PLoS ONE
The tomato AGC protein kinase Adi3 is a Ser/Thr kinase that functions as a negative regulator of programmed cell death through cell death suppression (CDS) activity in the nucleus. In this study, to understand the mechanism of Adi3 CDS, peptide micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2573ca66bfc53d29c846d4842b3552c4
https://doaj.org/article/c6e7f6d1a8b2405d94518726bcb63d4f
https://doaj.org/article/c6e7f6d1a8b2405d94518726bcb63d4f
Autor:
Sujata Chauhan, Anuradha Sourirajan, Kamal Dev, Jitendra K. Thakur, Subhasis Samanta, Nitin Sharma
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 12, Pp e03050-(2019)
Heliyon, Vol 5, Iss 12, Pp e03050-(2019)
Phosphorylation of proteins on serine/threonine residues represents an important biochemical mechanism to regulate several cellular processes. Polo-like kinases (PLKs) are a family of serine-threonine kinases that play an imminent role in cell cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a993ce37e0a1ff33b40c6f445067408
http://europepmc.org/articles/PMC7201137
http://europepmc.org/articles/PMC7201137
Kniha
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.