Zobrazeno 1 - 10
of 44
pro vyhledávání: '"in vitro comet assay"'
Publikováno v:
Mutagenesis. 37:248-258
Previous studies have shown that differences in experimental design factors may alter the potency of genotoxic compounds in in vitro genotoxicity tests. Most of these studies used traditional statistical methods based on the lowest observed genotoxic
Publikováno v:
İstanbul Journal of Pharmacy. 52:136-142
Background and Aims: Pesticide poisoning is the most widespread occupational hazard for agricultural workers in the developing world, due to the extensive presence of pesticides in the environment. The aim of this study was to investigate the cytotox
Akademický článek
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(Quantitative) structure-activity relationship ([Q]SAR) methodologies are widely applied to predict the (eco)toxicological effects of chemicals, and their use is envisaged in different regulatory frameworks for filling data gaps of untested substance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::86bcdb4dbc48bec77753af9a2acf2e1e
Autor:
Bossa, Cecilia, Andreoli, Cristina, Bakker, Martine, Barone, Flavia, De Angelis, Isabella, Jeliazkova, Nina, Nymark, Penny, Battistelli, Chiara Laura
(Quantitative) structure-activity relationship ([Q]SAR) methodologies are widely applied to predict the (eco)toxicological effects of chemicals, and their use is envisaged in different regulatory frameworks for filling data gaps of untested substance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::27b4896d718550fdb50d73e6450d4291
http://hdl.handle.net/10029/625381
http://hdl.handle.net/10029/625381
Akademický článek
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Autor:
Kerstin Reisinger
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
The 3D Skin Comet assay was developed to improve the in vitro prediction of the genotoxic potential of dermally applied chemicals. For this purpose, a classical read-out for genotoxicity (i.e. comet formation) was combined with reconstructed 3D skin
Externí odkaz:
https://doaj.org/article/9dccacecf2d84657b17261ed1a0cd030
Publikováno v:
Food Technology and Biotechnology, Vol 43, Iss 2, Pp 139-146 (2005)
A screening strategy for evaluation of genotoxic potential of drinking water has been proposed in the present work. Genotoxicity assays with tap water collected at three different sampling points in Ljubljana drinking water region are presented here.
Externí odkaz:
https://doaj.org/article/f6f132749e214efe8c61ba60279ec3d2
Even if the two neonicotinoids nitenpyram and imidacloprid have been considered safe for humans, their potential genotoxicity still remains a matter of discussion. The DNA-damaging effects of these two compounds were therefore evaluated in a lymphoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4aed517bdcef9e1ec253af45f13bc19
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397667
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397667
Autor:
Erik Bivehed, Björn Hellman
Publikováno v:
MethodsX, Vol 7, Iss, Pp 101161-(2020)
MethodsX
MethodsX
In the present paper, we present a substantially revised protocol of the widely used SCGE assay performed under alkaline conditions. In our updated version of the comet assay, which we call the Flash-comet, LiOH is used instead of NaOH during the unw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c625e1e6f655552b863d3e8eeba910
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-434712
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-434712