Zobrazeno 1 - 10
of 36
pro vyhledávání: '"immuunivaste"'
Autor:
Aysel Ahadova, Johannes Witt, Saskia Haupt, Richard Gallon, Robert Hüneburg, Jacob Nattermann, Sanne ten Broeke, Lena Bohaumilitzky, Alejandro Hernandez‐Sanchez, Mauro Santibanez‐Koref, Michael S. Jackson, Maarit Ahtiainen, Kirsi Pylvänäinen, Katarina Andini, Vince Kornel Grolmusz, Gabriela Möslein, Mev Dominguez‐Valentin, Pål Møller, Daniel Fürst, Rolf Sijmons, Gillian M. Borthwick, John Burn, Jukka‐Pekka Mecklin, Vincent Heuveline, Magnus von Knebel Doeberitz, Toni Seppälä, Matthias Kloor
Publikováno v:
International Journal of Cancer. 152:2024-2031
Lynch syndrome (LS) is the most common inherited cancer syndrome. It is inherited via a monoallelic germline variant in one of the DNA mismatch repair (MMR) genes. LS carriers have a broad 30-80% risk of developing various malignancies, and more prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ae9fe9c2966996be43707cfbe7c054
https://doi.org/10.1002/ijc.34312
https://doi.org/10.1002/ijc.34312
Autor:
Jouni Härkönen, Petri Pölönen, Ashik Jawahar Deen, Ilakya Selvarajan, Hanna-Riikka Teppo, Elitsa Y. Dimova, Thomas Kietzmann, Maarit Ahtiainen, Juha P. Väyrynen, Sara A. Väyrynen, Hanna Elomaa, Niko Tynkkynen, Tiia Eklund, Teijo Kuopio, Eva-Maria Talvitie, Pekka Taimen, Markku Kallajoki, Minna U. Kaikkonen, Merja Heinäniemi, Anna-Liisa Levonen
The NRF2 pathway is frequently activated in various cancer types, yet a comprehensive analysis of its effects across different malignancies is currently lacking. We developed a NRF2 activity metric and utilized it to conduct a pan-cancer analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9605b6d64564fd65840f4550fc55c79
http://urn.fi/URN:NBN:fi:jyu-202303132132
http://urn.fi/URN:NBN:fi:jyu-202303132132
Autor:
Jan Böhm, Anna Junttila, Sirpa Jalkanen, Jukka-Pekka Mecklin, Olli Helminen, Istvan Kenessey, Juha P. Väyrynen, Maarit Ahtiainen, Ilmo Kellokumpu, Johanna Mrena, Teijo Kuopio
Publikováno v:
British Journal of Cancer
Background Immune response against cancer has prognostic impact but its role in gastric cancer is poorly known. The aim of the study was to assess the prognostic significance of immune cell score (CD3+, CD8+), tumour immune escape (PD-L1, PD-1) and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c9abaf7c5c4374d8aa5295017ee602
http://europepmc.org/articles/PMC7687887
http://europepmc.org/articles/PMC7687887
Like many bacterial species, Borrelia burgdorferi, the pleomorphic bacterium that causes Lyme borreliosis, produces outer membrane vesicles (OMVs). Borrelial OMVs (BbOMVs) have been identified as containing virulence factors, such as outer surface pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1222::7de0f689c27e3cc4f8d18247782c90ce
http://urn.fi/URN:NBN:fi:jyu-202201271305
http://urn.fi/URN:NBN:fi:jyu-202201271305
Autor:
Hautala, Arto
Liikunta vahvistaa tutkitusti rokotusten tehoa. Liikuntaharrastus pienentää myös riskiä sairastua vakavaan koronatautiin. nonPeerReviewed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1222::ba15d81933cad40a9d0fe5dffbac3f75
http://urn.fi/URN:NBN:fi:jyu-202204262403
http://urn.fi/URN:NBN:fi:jyu-202204262403
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Lyme borreliosis is a multisystemic disease caused by the pleomorphic bacteria of the Borrelia burgdorferi sensu lato complex. The exact mechanisms for the infection to progress into a prolonged sequelae of the disease are currently unknown, although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b377e1602372e398d63d8fe79b50b12a
https://www.frontiersin.org/articles/10.3389/fmicb.2021.711291/full
https://www.frontiersin.org/articles/10.3389/fmicb.2021.711291/full
Autor:
Anna Lepistö, Jukka-Pekka Mecklin, Toni T. Seppälä, Erkki Ville Wirta, Ari Ristimäki, Päivi Peltomäki, Maarit Ahtiainen, Sanjeevi Ukwattage, Satu Mäki-Nevala
Publikováno v:
Biomolecules, Vol 11, Iss 1440, p 1440 (2021)
Biomolecules
Volume 11
Issue 10
Biomolecules
Volume 11
Issue 10
Immunological and epigenetic changes are interconnected and contribute to tumorigenesis. We determined the immunoprofiles and promoter methylation of inflammation-related genes for colitis-associated colorectal carcinomas (CA-CRC). The results were c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52b4cf6703b8ae459f71d2188118bef
https://trepo.tuni.fi/handle/10024/135286
https://trepo.tuni.fi/handle/10024/135286
Autor:
Maarit Ahtiainen, Hanna Elomaa, Juha P. Väyrynen, Erkki-Ville Wirta, Teijo Kuopio, Olli Helminen, Toni T. Seppälä, Ilmo Kellokumpu, Jukka-Pekka Mecklin
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1530, p 1530 (2021)
Cancers, Vol 13, Iss 1530, p 1530 (2021)
Simple Summary Metastasis is the main cause for cancer mortality. The most common metastatic sites of colorectal cancer (CRC) are the liver and lungs. Tumour-infiltrating lymphocytes are recognized as beneficial prognostic factors both in primary and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fc6461702e5a04139ec4bd00db9a7014
http://hdl.handle.net/10138/330816
http://hdl.handle.net/10138/330816
Autor:
Raija Tammi, Maarit Ahtiainen, Kyösti Tahkola, Jukka-Pekka Mecklin, Jan Böhm, Ilmo Kellokumpu, Juha P. Väyrynen, Johanna Laukkarinen, Markku Tammi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
Hyaluronan (HA) accumulation has been associated with poor survival in various cancers, but the mechanisms for this phenomenon are still unclear. The aim of this study was to investigate the prognostic significance of stromal HA accumulation and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf47242f1b12215b6c56e50cc4eed8e4
https://trepo.tuni.fi/handle/10024/133203
https://trepo.tuni.fi/handle/10024/133203