Pathogen-induced tissue-resident memory T H 17 (T RM 17) cells amplify autoimmune kidney disease

Autor: Leon U. B. Enk, Natascha E. Stumpf, Yu Zhao, Milagros N. Wong, Ulf Panzer, Clemens D. Cohen, Daniel Reimers, Stefanie Klinge, Constantin Schmidt, Christian Krebs, Christian Kurts, M. Rosemblatt, Sarah Nuñez, Nicola Gagliani, Catherine Meyer-Schwesinger, Thorsten Wiech, Tabea Bertram, Jan-Hendrik Riedel, Patricia Bartsch, Joanna Schmid, Christoph Kilian, Sören Franzenburg, Tobias B. Huber, Stefan Bonn, Alina Borchers, Maja T. Lindenmeyer, Jan-Eric Turner, Martina Becker, Hans-Joachim Paust, Friedrich Koch-Nolte, Michael Rink, María Rosa Bono, Holger Rohde, Elion Hoxha, Michael Zinke, Victor G. Puelles, Hans-Willi Mittrücker, Malte Hellmig, Samuel Huber

Publikováno v: Science immunology 5(50), eaba4163-(2020). doi:10.1126/sciimmunol.aba4163

Although it is well established that microbial infections predispose to autoimmune diseases, the underlying mechanisms remain poorly understood. After infection, tissue-resident memory T (TRM) cells persist in peripheral organs and provide immune pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a098b09e585e4ed93a16bf6c5ce5f7c3
https://doi.org/10.1126/sciimmunol.aba4163

Asymptomatic memory CD8+ T cells: From development and regulation to consideration for human vaccines and immunotherapeutics

Autor: Patricia P. Lopes, Lucas Gutierrez, Justin Cochrane, Thanh T. Pham, Christine Wang, Lbachir BenMohamed, Arif A. Khan, Ruchi Srivastava, Nhi Thi Uyen Thai

Publikováno v: Khan, Arif Azam; Srivastava, Ruchi; Lopes, Patricia Prado; Wang, Christine; Pham, Thanh T; Cochrane, Justin; et al.(2014). Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeutics.. Human vaccines & immunotherapeutics, 10(4), 945-963. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/16q0g0br

Generation and maintenance of high quantity and quality memory CD8(+) T cells determine the level of protection from viral, bacterial, and parasitic re-infections, and hence constitutes a primary goal for T cell epitope-based human vaccines and immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445ce955e4e7f1b21999452035a20a0d
https://europepmc.org/articles/PMC4896594/

Natural Suppression of Human Immunodeficiency Virus Type 1 Replication Is Mediated by Transitional Memory CD8+ T Cells ▿

Autor: Carl E. Johnson, Fernando Teque, Sue Fujimura, Jay A. Levy, M. Scott Killian

Publikováno v: Killian, M Scott; Johnson, Carl; Teque, Fernando; Fujimura, Sue; & Levy, Jay A. (2011). Natural suppression of human immunodeficiency virus type 1 replication is mediated by transitional memory CD8+ T cells.. Journal of virology, 85(4), 1696-16705. UC Office of the President: California HIV/AIDS Research Program. Retrieved from: http://www.escholarship.org/uc/item/8wt6w8hp

HIV replication is suppressed in vitro by a CD8 + cell noncytotoxic antiviral response (CNAR). This activity directly correlates with an asymptomatic clinical state. The objective of this study was to identify the phenotype of CD8 + cell subsets havi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a9755f02b3d045fdb035e7d8915d7d
https://europepmc.org/articles/PMC3028886/

Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis

Autor: Naomi Taylor, Sandrina Kinet, Maryam Burjanadze, Louise Swainson, Sara Jaleco, Valérie Dardalhon

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2003, 171 (1), pp.61--8. ⟨10.4049/jimmunol.171.1.61⟩

Cytokines play a crucial role in the maintenance of polyclonal naive and memory T cell populations. It has previously been shown that ex vivo, the IL-7 cytokine induces the proliferation of naive recent thymic emigrants (RTE) isolated from umbilical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39176c4557ab179c209c3274b2547d01
https://hal.archives-ouvertes.fr/hal-02199823

T-lymphocyte subsets, thymic size and breastfeeding in infancy.

Autor: Jeppesen, Dorthe L.¹ d.jeppcsen@dadlnet.dk, Hasselbalch, Helle², Lisse, Ida M.³, Ersbøll, Annette K.⁴, Engelmann, Mads D. M.⁵

Publikováno v: Pediatric Allergy & Immunology. Apr2004, Vol. 15 Issue 2, p127-132. 6p.