Zobrazeno 1 - 7
of 7
pro vyhledávání: '"immunology [Antibodies, Neutralizing]"'
Autor:
Nicholas C. Wu, Xueyong Zhu, Marit J. van Gils, Jakob Kreye, Chang-Chun D Lee, Linghang Peng, Hejun Liu, Meng Yuan, Abigail M. Jackson, Dennis R. Burton, Andrew B. Ward, Rogier W. Sanders, David Nemazee, S. Momsen Reincke, Harald Prüss, Ian A. Wilson, Deli Huang
Publikováno v:
Science 373(6556), 818-823 (2021). doi:10.1126/science.abh1139
bioRxiv
article-version (status) pre
article-version (number) 1
Science, 373(6556), 818-823. American Association for the Advancement of Science
Science (New York, N.y.)
bioRxiv
article-version (status) pre
article-version (number) 1
Science, 373(6556), 818-823. American Association for the Advancement of Science
Science (New York, N.y.)
The protective efficacy of neutralizing antibodies (nAbs) elicited during natural infection with SARS-CoV-2 and by vaccination based on its spike protein has been compromised with emergence of the recent SARS-CoV-2 variants. Residues E484 and K417 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a44f112f84d84b18800a45c2c75d8b9
http://www.scopus.com/inward/record.url?scp=85112522453&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85112522453&partnerID=8YFLogxK
Autor:
Folgerdiena M. de Vries, Marcel A. Müller, N. Ahmad Aziz, Antonio Schmandke, Marie Luisa Schmidt, Thomas H. Schmidt, Monique M.B. Breteler, Christian Drosten, Anja Richter, Antje K.C. Echterhoff, Victor M. Corman
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications 12(1), 2117 (2021). doi:10.1038/s41467-021-22351-5
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications 12(1), 2117 (2021). doi:10.1038/s41467-021-22351-5
To estimate the seroprevalence and temporal course of SARS-CoV-2 neutralizing antibodies, we embedded a multi-tiered seroprevalence survey within an ongoing community-based cohort study in Bonn, Germany. We first assessed anti-SARS-CoV-2 immunoglobul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ef61368b7115c5d2b2540984273656
https://pubmed.ncbi.nlm.nih.gov/33837204
https://pubmed.ncbi.nlm.nih.gov/33837204
Autor:
Julius Hoffmann, Laura Stöffler, Christian Drosten, Ian A. Wilson, Stefan Hippenstiel, Niels von Wardenburg, Jakob Trimpert, Xueyong Zhu, Dietmar Schmitz, Scott van Hoof, Andreas C. Hocke, Florian Kurth, Marcel A. Müller, Lucie Y Li, Hejun Liu, Leif E. Sander, Christiana Franke, Daria Vladimirova, Chang-Chun D Lee, Anja Richter, Marie Luisa Schmidt, Kristina Dietert, Elisa Sanchez-Sendin, Jakob Kreye, Karl Skriner, Harald Prüss, Lara Maria Jeworowski, Martin Witzenrath, Marie A Homeyer, Nikolaus Osterrieder, Nicholas C. Wu, Daniel Wendisch, Victor M. Corman, Paula Charlotte Barthel, Matthias Endres, Luca D. Bertzbach, Azza Abdelgawad, Meng Yuan, Norbert Suttorp, S. Momsen Reincke, Markus Höltje, Tatjana Schwarz, Hans Christian Kornau, Achim D. Gruber
Publikováno v:
Cell
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of virus-neutralizing antibodies and target epitopes is needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5418ec544a5ad15fbfd4125ba4fd2f9d
http://europepmc.org/articles/PMC7510528
http://europepmc.org/articles/PMC7510528
Autor:
Linghang Peng, Fangzhu Zhao, Meng Yuan, Xueyong Zhu, Dennis R. Burton, Hejun Liu, Nicholas C. Wu, Chang-Chun D Lee, Marit J. van Gils, David Nemazee, Deli Huang, Sandhya Bangaru, Ian A. Wilson, Hans Christian Kornau, Shawn Barman, Harald Prüss, Rogier W. Sanders, Jakob Kreye, S. Momsen Reincke, Andrew B. Ward
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
Cell host & microbe, 29(5), 806-818.e6. Cell Press
Cell host and microbe 29(5), 806-818.e6 (2021). doi:10.1016/j.chom.2021.04.005
Cell Host & Microbe
article-version (status) pre
article-version (number) 1
Cell host & microbe, 29(5), 806-818.e6. Cell Press
Cell host and microbe 29(5), 806-818.e6 (2021). doi:10.1016/j.chom.2021.04.005
Cell Host & Microbe
Coronaviruses have caused several human epidemics and pandemics including the ongoing coronavirus disease 2019 (COVID-19). Prophylactic vaccines and therapeutic antibodies have already shown striking effectiveness against COVID-19. Nevertheless, conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf08c7509dedd958cc92d18c46463d3
https://doi.org/10.1016/j.chom.2021.04.005
https://doi.org/10.1016/j.chom.2021.04.005
Autor:
Jay A. Levy, Gary Landucci, Sebastian Molnar, Donald N. Forthal, Vincent J. Venditto, Fernando Teque, Francis C. Szoka, Lindsay Wieczorek, Douglas S. Watson, Victoria R. Polonis
Publikováno v:
Venditto, Vincent J; Wieczorek, Lindsay; Molnar, Sebastian; Teque, Fernando; Landucci, Gary; Watson, Douglas S; et al.(2014). Chemically modified peptides based on the membrane-proximal external region of the HIV-1 envelope induce high-titer, epitope-specific nonneutralizing antibodies in rabbits.. Clinical and vaccine immunology : CVI, 21(8), 1086-1093. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/6tr4w04h
Broadly neutralizing monoclonal antibodies (bNAbs) 2F5 and 4E10 bind to the membrane proximal external region (MPER) of gp41 and also cross-react with phospholipids. In this study, we investigated if chemical modifications on the MPER adjacent to 2F5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de03463494e1aea876e6f8173e3c099f
https://doi.org/10.1128/cvi.00320-14
https://doi.org/10.1128/cvi.00320-14
Autor:
Donald Stablein, Jerome H. Kim, Peter Abbink, Lori F. Maxfield, Angela Carville, Mangala Rao, Michael S. Seaman, Hualin Li, Vanessa M. Hirsch, Keith G. Mansfield, Jerald C. Sadoff, Diana M. Lynch, Maria G. Pau, Erik Billings, Adam J. SanMiguel, Nelson L. Michael, Hanneke Schuitemaker, Donald N. Forthal, Mary A. Marovich, Dan H. Barouch, Ilnour Ourmanov, Jaap Goudsmit, M. Justin Iampietro, Merlin L. Robb, Jinyan Liu, Guido Ferrari
Publikováno v:
Nature, 482(7383), 89-93. Nature Publishing Group
Barouch, Dan H; Liu, Jinyan; Li, Hualin; Maxfield, Lori F; Abbink, Peter; Lynch, Diana M; et al.(2012). Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys.. Nature, 482(7383), 89-893. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/7fj1p3tb
Barouch, Dan H; Liu, Jinyan; Li, Hualin; Maxfield, Lori F; Abbink, Peter; Lynch, Diana M; et al.(2012). Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys.. Nature, 482(7383), 89-893. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/7fj1p3tb
Preclinical studies of human immunodeficiency virus type 1 (HIV-1) vaccine candidates have typically shown post-infection virological control, but protection against acquisition of infection has previously only been reported against neutralization-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7aaefacaace98bd1f2383bed28b381
https://pubmed.ncbi.nlm.nih.gov/22827240
https://pubmed.ncbi.nlm.nih.gov/22827240
Autor:
S. Momsen Reincke, Meng Yuan, Hans-Christian Kornau, Victor M. Corman, Scott van Hoof, Elisa Sánchez-Sendin, Melanie Ramberger, Wenli Yu, Yuanzi Hua, Henry Tien, Marie Luisa Schmidt, Tatjana Schwarz, Lara Maria Jeworowski, Sarah E. Brandl, Helle Foverskov Rasmussen, Marie A. Homeyer, Laura Stöffler, Martin Barner, Désirée Kunkel, Shufan Huo, Johannes Horler, Niels von Wardenburg, Inge Kroidl, Tabea M. Eser, Andreas Wieser, Christof Geldmacher, Michael Hoelscher, Hannes Gänzer, Günter Weiss, Dietmar Schmitz, Christian Drosten, Harald Prüss, Ian A. Wilson, Jakob Kreye
Publikováno v:
Science
Science / Science now 375(6582), 782-787 (2022). doi:10.1126/science.abm5835
Science / Science now 375(6582), 782-787 (2022). doi:10.1126/science.abm5835
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Beta variant of concern (VOC) resists neutralization by major classes of antibodies from COVID-19 patients and vaccinated individuals. In this study, serum of Beta-infected patients reveale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d951ee790a7e70bb217671f85941ff9