Zobrazeno 1 - 10
of 121
pro vyhledávání: '"immunological non-responders"'
Autor:
Xianwu Pang, Qin He, Jinghua Huang, Kailing Tang, Ningye Fang, Haomin Xie, Jie Ma, Qiuying Zhu, Guanghua Lan, Shujia Liang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The prevalence of AIDS and mortality rates among HIV-infected individuals in Guangxi remain relatively high, potentially due to impaired CD4 + cell recovery. This study aims to identify factors hindering CD4 + cell recovery in people living
Externí odkaz:
https://doaj.org/article/ddcda607b5b041efa9e19ae5e8100f9f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundAlthough MDSCs are widely recognized for their immunoinhibitory effects in pathological conditions, their function during HIV infection particularly within the mechanisms underlying incomplete immune recovery remains elusive.MethodsWe condu
Externí odkaz:
https://doaj.org/article/0d1ac77ace984d5a9bfa0399c218d41c
Autor:
Yang Zhang, Jiahao Ji, Luyao Zheng, Miaotian Cai, Guangqiang Sun, Yundong Ma, Xin Zhang, Xue Chen, Yulin Zhang, Xiao Lin, Zhen Li, Tong Zhang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPeople living with HIV (PLWH), especially immunological non-responders (INRs), may experience adverse neurologic events. However, the extent of neurological impairment in INRs remains uncertain. This study evaluates brain structure and func
Externí odkaz:
https://doaj.org/article/04394d9969ba46fc8f41b2a8f0ef442a
Autor:
Xiuhan Yang, Cheng Zhen, Huihuang Huang, Yanmei Jiao, Xing Fan, Chao Zhang, Jinwen Song, Songshan Wang, Chunbao Zhou, XinXin Yang, Jinhong Yuan, Jiyuan Zhang, Ruonan Xu, Fu-Sheng Wang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Increased CD4+GNLY+ T cells have been confirmed to be inversely associated with CD4+ T cell count in immunological non-responders (INRs), however, the underlying mechanisms are unknown. This study aimed to elucidate the characteristics of CD4+GNLY+ T
Externí odkaz:
https://doaj.org/article/8b456b83ac4e433d8662e830410734f1
Autor:
Esperanza Muñoz-Muela, María Trujillo-Rodríguez, Ana Serna-Gallego, Abraham Saborido-Alconchel, Carmen Gasca-Capote, Ana Álvarez-Ríos, Ezequiel Ruiz-Mateos, Dmitri Sviridov, Andrew J. Murphy, Man K.S. Lee, Luis F. López-Cortés, Alicia Gutiérrez-Valencia
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105338- (2024)
Summary: Background: Among people living with HIV-1 (PHIV), immunological non-responders (INR) experience incomplete immune recovery despite suppressive antiretroviral treatment (ART), facing more severe non-AIDS events than immunological responders
Externí odkaz:
https://doaj.org/article/47ad10b8ca9a4c4b83f25cd317d658ff
Autor:
Wilhelm A. J. W. Vos, Adriana Navas, Elise M. G. Meeder, Marc J. T. Blaauw, Albert L. Groenendijk, Louise E. van Eekeren, Twan Otten, Nadira Vadaq, Vasiliki Matzaraki, Bram van Cranenbroek, Kees Brinkman, Jan van Lunzen, Leo A. B. Joosten, Mihai G. Netea, Willem L. Blok, Andre J. A. M. van der Ven, Hans J. P. M. Koenen, Janneke E. Stalenhoef
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmunological non-responders (INR) are people living with HIV (PLHIV) who fail to fully restore CD4+ T-cell counts despite complete viral suppression with antiretroviral therapy (ART). INR are at higher risk for non-HIV related morbidity
Externí odkaz:
https://doaj.org/article/fe9f62a30ced4509bab65036784e5714
Publikováno v:
Infection and Drug Resistance, Vol Volume 16, Pp 3871-3878 (2023)
Xuebin Tian,1,2,* Yiwen Xie,1,2,* Jingjing Chen,3,* Wanpeng Yin,1,2 Yu Long Zhao,1 Peng Yao,4 Mingqing Dong,4 Changzhong Jin,1,2 Nanping Wu1,2 1Cell Biology Research Platform, Jinan Microecological Biomedicine Shandong Laboratory, Jinan,
Externí odkaz:
https://doaj.org/article/04f487a8996240628ddd588eb6415903
Autor:
Maria Carolina Santos Guedes, Wlisses Henrique Veloso Carvalho-Silva, José Leandro Andrade-Santos, Maria Carolina Accioly Brelaz-de-Castro, Fabrício Oliveira Souto, Lílian Maria Lapa Montenegro, Rafael Lima Guimarães
Publikováno v:
Vaccines, Vol 12, Iss 6, p 612 (2024)
The mechanisms underlying unsatisfactory immune reconstitution in HIV-1 positive patients under ART have not been fully elucidated, even after years of investigation. Thus, this study aimed to assess the correlation between age and thymic production
Externí odkaz:
https://doaj.org/article/bfe134a62fdd459194df6263d2018b8b
Autor:
Xiao-Yan Guo, Yun-Tian Guo, Ze-Rui Wang, Yan-Mei Jiao, Yue Hu, Li-Na Fan, Rui-Qin Cheng, Meng-Meng Qu, Chao Zhang, Jin-Wen Song, Ruo-Nan Xu, Xing Fan, Wen Xu, Ji-Yuan Zhang, Bing-Ke Bai, En-Qiang Linghu, Yao-Kai Chen, Ping Ma, Fu-Sheng Wang
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20790- (2023)
The intestinal epithelial barrier plays an important role during human immunodeficiency virus (HIV) disease progression. However, the extent to which the intestinal epithelial barrier is damaged in immunological non-responders (INRs) and immunologica
Externí odkaz:
https://doaj.org/article/714f65a1bd9046f296a5a998386a8594
Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 8491-8507 (2022)
Qing Xiao,1,2 Junyan Han,3– 6 Fengting Yu,1– 3 Liting Yan,1,2 Qun Li,1,2 Xiaojie Lao,1,2 Hongxin Zhao,1,2 Fujie Zhang1,2 1Department of Infectious Diseases, Capital Medical University Affiliated Beijing Ditan Hospital, Beijing, People’s Republi
Externí odkaz:
https://doaj.org/article/d9d0802c5a8c4e4c80f7faf05a3dbfba