Zobrazeno 1 - 10
of 441
pro vyhledávání: '"immunoengineering"'
Publikováno v:
Small Science, Vol 4, Iss 9, Pp n/a-n/a (2024)
Lipid nanoparticles and polymeric nanoparticles are promising biomaterial platforms for robust intracellular DNA and mRNA delivery, highlighted by the widespread use of nanoparticle‐ (NP) based mRNA vaccines to help end the COVID‐19 pandemic. Rec
Externí odkaz:
https://doaj.org/article/a2842bce272b48089fc9cd67f85c332b
Autor:
Norman M. Drzeniek, Nourhan Kahwaji, Samira Picht, Ioanna Maria Dimitriou, Stephan Schlickeiser, Hanieh Moradian, Sven Geissler, Michael Schmueck‐Henneresse, Manfred Gossen, Hans‐Dieter Volk
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Beyond SARS‐CoV2 vaccines, mRNA drugs are being explored to overcome today's greatest healthcare burdens, including cancer and cardiovascular disease. Synthetic mRNA triggers immune responses in transfected cells, which can be reduced by c
Externí odkaz:
https://doaj.org/article/bc87cdf8b17443f38594ddec9b4f61d5
Autor:
Katharina Schmalkuche, Tamina Rother, Jonathan M. Burgmann, Henrike Voß, Klaus Höffler, Günes Dogan, Arjang Ruhparwar, Jan D. Schmitto, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Heart transplantation is associated with major hurdles, including the limited number of available organs for transplantation, the risk of rejection due to genetic discrepancies, and the burden of immunosuppression. In this study, we demonstrated the
Externí odkaz:
https://doaj.org/article/7159c2abd33b4a21b8e9532868962379
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Traumatic spinal cord injury (SCI), often resulting from external physical trauma, initiates a series of complex pathophysiological cascades, with severe cases leading to paralysis and presenting significant clinical challenges. Traditional diagnosti
Externí odkaz:
https://doaj.org/article/1c1a29b77af14f239dbcf3ed3dc9e300
Autor:
Carolina Gomez Casas, Anita Shukla
Publikováno v:
Frontiers in Biomaterials Science, Vol 2 (2024)
Modulating the immune system using engineered materials is an emerging strategy to combat bacterial infections. Bacteria adopt immune evasion strategies to ensure their survival, ultimately leading to persistence and recurrence of infections. With a
Externí odkaz:
https://doaj.org/article/b25e33c43b99499295f9e0c415e84457
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100869- (2023)
New experimental approaches for tissue repair have recently been proposed and include the application of natural or synthetic biomaterials and immune cells. Herein, fully synthetic poly(glycidyl ether) (PGE) copolymer coatings are evaluated as bioins
Externí odkaz:
https://doaj.org/article/da9c98a451304ab2b415cd90b2baa681
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100836- (2023)
Regeneration in the therapeutics of spinal cord injury (SCI) remains a challenge caused by the hyperinflammation microenvironment. Nanomaterials-based treatment strategies for diseases with excellent therapeutic efficacy are actively pursued. Here, w
Externí odkaz:
https://doaj.org/article/557a0298e8fd4f3d9996966a9c3d2879
T Cell engineering for cancer immunotherapy by manipulating mechanosensitive force-bearing receptors
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
T cell immune responses are critical for in both physiological and pathological processes. While biochemical cues are important, mechanical cues arising from the microenvironment have also been found to act a significant role in regulating various T
Externí odkaz:
https://doaj.org/article/d2919a3c8830436482cd7c18f0070c38
Publikováno v:
OpenNano, Vol 10, Iss , Pp 100124- (2023)
Chimeric antigen receptor (CAR) T cell treatment is an emerging subject following its curative response in hematological metastasis. However, solid tumors present a number of obstructions which have been a bull's eye to steer the CARs toward another
Externí odkaz:
https://doaj.org/article/369efb26870e47329144d3dd506f7d1f
Publikováno v:
Nano Convergence, Vol 9, Iss 1, Pp 1-31 (2022)
Abstract Immunotherapy has reached clinical success in the last decade, with the emergence of new and effective treatments such as checkpoint blockade therapy and CAR T-cell therapy that have drastically improved patient outcomes. Still, these therap
Externí odkaz:
https://doaj.org/article/11edc2c66ca64f0ca266c274fa7ba35a