Zobrazeno 1 - 10
of 153
pro vyhledávání: '"immunity therapy"'
Publikováno v:
Acta Materia Medica, Vol 2, Iss 2, Pp 216-227 (2023)
Neuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship. Stimulator of interferon genes (STING) agonists, particularly cyclic dinucleotide (CDN)
Externí odkaz:
https://doaj.org/article/84bbb502a6494f87b0b3b017a1452ebb
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 97 (2024)
Background: Basic leucine zipper and W2 domains 2 (BZW2), a member of the basic domain leucine zipper superfamily of transcription factors, has been implicated in the development and progression of various cancers. However, the precise biological rol
Externí odkaz:
https://doaj.org/article/0584e924a743433e8f6f260e2d2691d5
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Clear cell renal cell carcinoma is a common malignant tumor of the urinary system. The mechanism of its occurrence and development is unknown, and there is currently few effective comprehensive predictive markers for prognosis and treatment
Externí odkaz:
https://doaj.org/article/aa2e1754d19a4b6a9b88a5dc6feab698
Autor:
Jianfeng Li, Xizhe Liu, Huachuan Wu, Peng Guo, Baoliang Li, Jianmin Wang, Wei Tian, Dafu Chen, Manman Gao, Zhiyu Zhou, Shaoyu Liu
Publikováno v:
FEBS Open Bio, Vol 12, Iss 10, Pp 1839-1856 (2022)
Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage. To characteriz
Externí odkaz:
https://doaj.org/article/7ace5a978e6e4370b8f98716a035f515
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Colorectal cancer liver metastasis is a major risk factor of poor outcomes, necessitating proactive interventions and treatments. Cancer-associated fibroblasts (CAFs) play essential roles in metastasis, with a focus on metabolic reprogram
Externí odkaz:
https://doaj.org/article/54e6cd9f31e0498a89d086f26b1b0522
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Ovarian Serous Adenocarcinoma is a malignant tumor originating from epithelial cells and one of the most common causes of death from gynecological cancers. The objective of this study was to develop a prediction model based on extracellul
Externí odkaz:
https://doaj.org/article/ac63441fe461402394e74f044a48265f
Autor:
Wenshuai Li, Xuanxuan Pan, Lirong Chen, Haoshu Cui, Shaocong Mo, Yida Pan, Yuru Shen, Menglin Shi, Jianlin Wu, Feifei Luo, Jie Liu, Na Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Adoptive cell therapy (ACT) using chimeric antigen receptor (CAR)-modified T cells has revolutionized the field of immune-oncology, showing remarkable efficacy against hematological malignancies. However, its success in solid tumors is limited by fac
Externí odkaz:
https://doaj.org/article/f045da456b054ea498725839ea03d3ed
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 134-144 (2022)
Choroidal neovascularization (CNV) is a common pathological feature of various eye diseases and an important cause of visual impairment in middle-aged and elderly patients. In previous studies, tetrahedral framework nucleic acids (tFNAs) showed good
Externí odkaz:
https://doaj.org/article/a368671f7e6a4df780442ef28b4c3d4c
Autor:
Hongwei Luo, Que Zhang, Xiangchu Liu, Yue Luo, Xing Jiang, Chao Wang, Bin Chen, Qiming He, Yingchun Zhang, Ou Shu, Penggao Dai, Chengcheng He
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundColon cancer is one of the common cancers, and its prognosis remains to be improved. The role of cuproptosis as a newly discovered form of cell death in the development of colon cancer has not been determined.MethodsBased on 983 colon cance
Externí odkaz:
https://doaj.org/article/e57dbbf948684c268ea705c69bbe8aab
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundC15orf48 was recently identified as an inflammatory response-related gene; however there is limited information on its function in tumors. In this study, we aimed to elucidate the function and potential mechanism of action of C15orf48 in ca
Externí odkaz:
https://doaj.org/article/00f5aadf411641ce93b573ad0cd00355