Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants?

Autor: Philip Mwimanzi, Tristan J. Markle, Mark A. Brockman, Takamasa Ueno

Publikováno v: Viruses, Vol 4, Iss 9, Pp 1711-1730 (2012)

HIV-1 causes a chronic infection in humans that is characterized by high plasma viremia, progressive loss of CD4+ T lymphocytes, and severe immunodeficiency resulting in opportunistic disease and AIDS. Viral persistence is mediated in part by the abi

Externí odkaz: https://doaj.org/article/3fb9a439095c425c960a0c5c885bef5b

Genetic variability in G2 and F2 region between biological clones of human respiratory syncytial virus with or without host immune selection pressure

Autor: Sandra Elisabete Vieira, Viviane Fongaro Botosso, Hildener Nogueira Lima, Edison Luiz Durigon, Klaus Eberhard Stewien, Patrícia Alves Ramos Bosso, Claudia T. P. Moraes, Danielle Bruna Leal Oliveira, Angélica Cristine de Almeida Campos, Alfredo Elias Gilio

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 110, Issue: 1, Pages: 138-141, Published: 03 FEB 2015
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz., Vol 110, Iss 1, Pp 138-141 (2015)

Human respiratory syncytial virus (HRSV) is an important respiratory pathogens among children between zero-five years old. Host immunity and viral genetic variability are important factors that can make vaccine production difficult. In this work, dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859a5c4fed642251ca57908f3a11e667
https://doi.org/10.1590/0074-02760140299

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