Zobrazeno 1 - 10
of 14 151
pro vyhledávání: '"immune infiltration"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Percutaneous coronary intervention (PCI) combined with stent implantation is currently one of the most effective treatments for coronary artery disease (CAD). However, in-stent restenosis (ISR) significantly compromises its long-term efficac
Externí odkaz:
https://doaj.org/article/2e4d66281174405084367e12d84b5df7
Autor:
Lai Jiang, Shengke Zhang, Chenglu Jiang, Haiqing Chen, Jinbang Huang, Jinyan Yang, Hao Chi, Qibiao Wu, Guanhu Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Background We aimed to pinpoint biomarkers, create a diagnostic model for ulcerative colitis (UC), and delve into its immune features to better understand this autoimmune condition. Methods The sequencing data for both the UC and the control
Externí odkaz:
https://doaj.org/article/bac5ad6f0b064f889a3758d9258616c4
Autor:
Shizhuan Huang, Dehai Wu, Guanqun Liao, Ming Liang, Yaohui Zhang, Haotian Wu, Daowei Tang, Dixiang Wen, Bo Jiang, Shan Yu, Sheng Tai
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Oncolytic viral immunotherapy is a cancer treatment that uses native or genetically modified viruses that selectively replicate and destroy tumor cells. In this study, we aimed to construct a virus-based prognostic model for risk assessment
Externí odkaz:
https://doaj.org/article/2817421759c24ee385cf614547061850
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is a major tumor that seriously threatens the health of the head and neck or mucosal system. It is manifested as a malignant phenotype of high metastasis and invasion caused by squamou
Externí odkaz:
https://doaj.org/article/85d086955666477c928c22d00686b50c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Mitochondrial dysfunction and immune cell infiltration play crucial yet incompletely understood roles in the pathogenesis of calcific aortic valve disease (CAVD). This study aimed to identify immune-related mitochondrial genes critical to th
Externí odkaz:
https://doaj.org/article/54511181e05c43ad9b8034fd8d66db39
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Ficolins (FCNs) are a family of proteins, comprising FCN1, FCN2 and FCN3, and integral to the immune system which have been implicated in the onset and progression of tumors. Despite their recognized roles, a comprehensive analysi
Externí odkaz:
https://doaj.org/article/f1bbcfad4d13461ca87b8226b93345da
Autor:
Ping Cui, Jie Lian, Yang Liu, Dongsheng Zhang, Yao Lin, Lili Lu, Li Ye, Hui Chen, Sanqi An, Jiegang Huang, Hao Liang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract SHP-1, a nonreceptor protein tyrosine phosphatase encoded by ptpn6, has been regarded as a regulatory protein of hematopoietic cell biology for years. However, there is now increasing evidence to support its role in tumors. Thus, the role of
Externí odkaz:
https://doaj.org/article/ad2ae300b8844bd4bed0d003d8b4fb02
Autor:
Yingying Lian, Jiahao Chen, Jiayang Han, Binbin Zhao, Jialin Wu, Xinyu Li, Man Yue, Mengwen Hou, Tinggai Wu, Ting Ye, Xu Han, Tiantian Sun, Mengjie Tu, Kaifeng Zhang, Guangchao Liu, Yang An
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Liposarcoma (LPS) is the second most common kind of soft tissue sarcoma, and a heterogeneous malignant tumor derived from adipose tissue. Up to now, the prognostic value of BAG1 or BAG2 in LPS has not been defined yet. Expression profiling d
Externí odkaz:
https://doaj.org/article/6f3fe90365e747fbb326575965d87632
Autor:
Jie Zhou, Na Zhang, Yan Zuo, Feng Xu, Lihua Cheng, Yuanyuan Fu, Fudong Yang, Min Shu, Mi Zhou, Wenting Zou, Shengming Zhang
Publikováno v:
Hereditas, Vol 161, Iss 1, Pp 1-13 (2024)
Abstract Background Acute myeloid leukemia (AML) is a genetically heterogeneous disease in which glutamine (Gln) contributes to AML progression. Therefore, this study aimed to identify potential prognostic biomarkers for AML based on Gln metabolism-r
Externí odkaz:
https://doaj.org/article/04093c080c824eae95020b6a86d2b812
Autor:
Zhong-Yuan Meng, Chuang-Hong Lu, Jing Li, Juan Liao, Hong Wen, Yuan Li, Feng Huang, Zhi-Yu Zeng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Evidences illustrate that cell senescence contributes to the development of pulmonary arterial hypertension. However, the molecular mechanisms remain unclear. Since there may be different senescence subtypes between PAH patients, consistent
Externí odkaz:
https://doaj.org/article/dc6326ec35ce4a95ae43f1f98598f7c7