Zobrazeno 1 - 10
of 121
pro vyhledávání: '"immune checkpoint blockades"'
Autor:
Siyuan Wang, Jiaxin Wang, Yu Xia, Le Zhang, Yueqiang Jiang, Man Liu, Qinglei Gao, Cuntai Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Immune checkpoint blockades have been prized in circumventing and ablating the impediments posed by immunosuppressive receptors, reaching an exciting juncture to be an innovator in anticancer therapy beyond traditional therapeutics. Thus far
Externí odkaz:
https://doaj.org/article/77f363f5e14d4aeab513802a2e6c149d
Autor:
Jianheng Peng, Zhongjun Wu
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Purpose To evaluate the role and landscape of 5-10-Methylenetetrahydrofolate reductase (MTHFR) to immune infiltration, tumor microenvironment, heterogeneity, immune checkpoints blockades, prognostic significance across cancer types. Methods
Externí odkaz:
https://doaj.org/article/15c2638320d84b95805eaf48e783db02
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 795 (2024)
Cancer immunotherapy has revolutionized oncology by harnessing the patient’s immune system to target and eliminate cancer cells. However, immune checkpoint blockades (ICBs) face limitations such as low response rates, particularly in immunologicall
Externí odkaz:
https://doaj.org/article/40e892202a84467598fe4431fd8bda8b
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-63 (2022)
Abstract The United States Food and Drug Administration (US FDA) has always been a forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs (excluding vaccines, cell-based therapies, and gene therapy products) have been appro
Externí odkaz:
https://doaj.org/article/d9ea2987c29543299d69f58f85d7356a
Autor:
Neda Minaei, Roya Ramezankhani, Atena Tamimi, Abbas Piryaei, Ali Zarrabi, Amir Reza Aref, Ebrahim Mostafavi, Massoud Vosough
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 1, Pp 151284- (2023)
Hepatocellular carcinoma (HCC) is the most common type of primary hepatic cancer and is among the major causes of mortality due to cancer. Due to the lack of efficient conventional therapeutic options for this cancer, particularly in advanced cases,
Externí odkaz:
https://doaj.org/article/60ed9f1af6bd4435aca2fbd9b4ed02ed
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-30 (2021)
Abstract Tumor immunotherapy has attracted more and more attention nowadays, and multiple clinical trials have confirmed its effect in a variety of solid tumors. Immune checkpoint inhibitors (ICIs), cancer vaccines, adoptive cell transfer (ACT), and
Externí odkaz:
https://doaj.org/article/dfd598a5a37b41a0ba727d2fb96b4b14
Autor:
Seo Ree Kim, Sang Hoon Chun, Joo Ri Kim, Sang-Yeob Kim, Jun Young Seo, Chan Kwon Jung, Bo-Mi Gil, Jeong-Oh Kim, Yoon Ho Ko, In Sook Woo, Byoung Yong Shim, Sook-Hee Hong, Jin Hyoung Kang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Immune checkpoint blockades (ICBs) are characterized by a durable clinical response and better tolerability in patients with a variety of advanced solid tumors. However, we not infrequently encounter patients with hyperprogressive
Externí odkaz:
https://doaj.org/article/af7c81e1bb04464fa55c054aae8776d3
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Small cell lung cancer (SCLC) is one of the deadliest cancer types in the world. Despite the high response rate to frontline platinum-containing doublets, relapse is inevitable for the majority of patients and the prognosis is poor. Topoteca
Externí odkaz:
https://doaj.org/article/5ca230a92cde4bd0a624d41855e573d0
Autor:
Xiaoyan Wang, Bingchen Wu, Zhengqing Yan, Guoqiang Wang, Shiqing Chen, Jian Zeng, Feng Tao, Bichun Xu, Honggang Ke, Mei Li
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The common gamma receptor–dependent cytokines and their JAK-STAT pathways play important roles in T cell immunity and have been demonstrated to be related with response to immune checkpoint blockades (ICBs). PTPRD and PTPRT are phosphatases involve
Externí odkaz:
https://doaj.org/article/01b10a7acc604c4da996add6d718bf71
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