Zobrazeno 1 - 10 of 424 516 pro vyhledávání: '"immune “cold” tumor"'
1
Akademický článek
Tuning Immune‐Cold Tumor by Suppressing USP10/B7‐H4 Proteolytic Axis Reinvigorates Therapeutic Efficacy of ADCs.
Autor: Zeng, Lidan1,2 (AUTHOR), Zhu, Yueming1,2 (AUTHOR), Cui, Xin1,2 (AUTHOR), Chi, Junlong1,3 (AUTHOR), Uddin, Amad1,2 (AUTHOR), Zhou, Zhuan4 (AUTHOR), Song, Xinxin4 (AUTHOR), Dai, Mingji1,5 (AUTHOR), Cristofanilli, Massimo6 (AUTHOR), Kalinsky, Kevin2,7 (AUTHOR), Wan, Yong1,2,7 (AUTHOR) yong.wan@emory.edu
Publikováno v: Advanced Science. 10/28/2024, Vol. 11 Issue 40, p1-20. 20p.
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2
Akademický článek
Optimized patient-specific immune checkpoint inhibitor therapies for cancer treatment based on tumor immune microenvironment modeling.
Autor: Yao, Yao1 (AUTHOR), Chen, Youhua Frank2 (AUTHOR), Zhang, Qingpeng3,4 (AUTHOR) qpzhang@hku.hk
Publikováno v: Briefings in Bioinformatics. Nov2024, Vol. 25 Issue 6, p1-10. 10p.
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3
Akademický článek
Tuning Immune‐Cold Tumor by Suppressing USP10/B7‐H4 Proteolytic Axis Reinvigorates Therapeutic Efficacy of ADCs
Autor: Lidan Zeng, Yueming Zhu, Xin Cui, Junlong Chi, Amad Uddin, Zhuan Zhou, Xinxin Song, Mingji Dai, Massimo Cristofanilli, Kevin Kalinsky, Yong Wan
Publikováno v: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Tuning immune‐cold tumor hot has largely attracted attention to improve cancer treatment, including immunotherapy and antibody‐drug conjugates (ADCs). Utilizing multiomic analyses and experimental validation, this work identifies a pivot
Externí odkaz: https://doaj.org/article/226b8baa18054f7db917c92399c165fc
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4
Akademický článek
Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma.
Autor: Shi, Yewen1,2 (AUTHOR), Xie, Tongxin1 (AUTHOR), Wang, Bingbing1 (AUTHOR), Wang, Rong3 (AUTHOR), Cai, Yu4 (AUTHOR), Yuan, Bo5 (AUTHOR), Gleber-Netto, Frederico O.1 (AUTHOR), Tian, Xiangjun6 (AUTHOR), Rodriguez-Rosario, Alanis E.1,7 (AUTHOR), Osman, Abdullah A.1 (AUTHOR), Wang, Jing6 (AUTHOR), Pickering, Curtis R.1 (AUTHOR), Ren, Xiaoyong2 (AUTHOR), Sikora, Andrew G.1 (AUTHOR), Myers, Jeffrey N.1 (AUTHOR) jmyers@mdanderson.org, Rangel, Roberto1 (AUTHOR) rrangel@mdanderson.org
Publikováno v: Communications Biology. 7/28/2022, Vol. 5 Issue 1, p1-14. 14p.
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5
Akademický článek
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6
Akademický článek
Penetrable Nanoplatform for "Cold" Tumor Immune Microenvironment Reeducation.
Autor: Chen, Qinjun1 (AUTHOR), He, Yongqing1 (AUTHOR), Wang, Yu1 (AUTHOR), Li, Chao1 (AUTHOR), Zhang, Yujie1 (AUTHOR), Guo, Qin1 (AUTHOR), Zhang, Yiwen1 (AUTHOR), Chu, Yongchao1 (AUTHOR), Liu, Peixin1 (AUTHOR), Chen, Hongyi1 (AUTHOR), Zhou, Zheng1 (AUTHOR), Zhou, Wenxi1 (AUTHOR), Zhao, Zhenhao1 (AUTHOR), Li, Xiaomin2 (AUTHOR), Sun, Tao1 (AUTHOR), Jiang, Chen1 (AUTHOR) jiangchen@shmu.edu.cn
Publikováno v: Advanced Science. 9/9/2020, Vol. 7 Issue 17, p1-15. 15p.
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7
Akademický článek
Comprehensive Immune Profiling Unveils a Subset of Leiomyosarcoma with "Hot" Tumor Immune Microenvironment.
Autor: Feng, Xiaolan1 (AUTHOR) fxiaolan@ucalgary.ca, Tonon, Laurie2 (AUTHOR), Li, Haocheng3 (AUTHOR), Darbo, Elodie4 (AUTHOR), Pleasance, Erin5 (AUTHOR), Macagno, Nicolas6 (AUTHOR), Dufresne, Armelle7 (AUTHOR), Brahmi, Mehdi7 (AUTHOR), Bollard, Julien7 (AUTHOR), Ducimetière, Francoise7 (AUTHOR), Karanian, Marie8 (AUTHOR), Meurgey, Alexandra8 (AUTHOR), Pérot, Gaëlle9 (AUTHOR), Valentin, Thibaud9 (AUTHOR), Chibon, Frédéric9 (AUTHOR), Blay, Jean-Yves10 (AUTHOR) jean-yves.blay@lyon.unicancer.fr
Publikováno v: Cancers. Jul2023, Vol. 15 Issue 14, p3705. 23p.
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8
Akademický článek
Mutant p53 drives an immune cold tumor immune microenvironment in oral squamous cell carcinoma
Autor: Yewen Shi, Tongxin Xie, Bingbing Wang, Rong Wang, Yu Cai, Bo Yuan, Frederico O. Gleber-Netto, Xiangjun Tian, Alanis E. Rodriguez-Rosario, Abdullah A. Osman, Jing Wang, Curtis R. Pickering, Xiaoyong Ren, Andrew G. Sikora, Jeffrey N. Myers, Roberto Rangel
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Oral squamous cell carcinoma models are presented with defined Trp53 mutations associated with immune checkpoint inhibitor responsiveness, e.g. T122N amino acid change of Tp53 promotes a cold TME enriched with immunosuppressive M2 macrophages resista
Externí odkaz: https://doaj.org/article/57f97433af1f465f8833d69d49cf18b1
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9
Akademický článek
Photothermally sensitive gold nanocage augments the antitumor efficiency of immune checkpoint blockade in immune 'cold' tumors
Autor: Guixiu Xiao, Yujie Zhao, Xueyan Wang, Chuan Zeng, Feng Luo, Jing Jing
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionImmune checkpoint blockade (ICB) has revolutionized the therapy landscape of malignancy melanoma. However, the clinical benefits from this regimen remain limited, especially in tumors lacking infiltrated T cells (known as “cold” tumor
Externí odkaz: https://doaj.org/article/ecf7008ee2df4b6da46acfa6fd9b25de
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10
Akademický článek
Pan-cancer analysis of TASL: a novel immune infiltration-related biomarker for tumor prognosis and immunotherapy response prediction.
Autor: Li, Huanyu1,2 (AUTHOR), Sun, Xiaoyu1,2 (AUTHOR), Zhao, Yanyun1,2 (AUTHOR), Zhang, Changzhu1,2 (AUTHOR), Jiang, Kai1,2 (AUTHOR), Ren, Jie1,2 (AUTHOR) renjie_cmu2013@163.com, Xing, Lijuan3 (AUTHOR) xinglijuan1972@163.com, He, Miao1,2 (AUTHOR) hemiao_cmu@126.com
Publikováno v: BMC Cancer. 6/9/2023n, Vol. 23 Issue 1, p1-22. 22p.
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