Zobrazeno 1 - 10
of 260
pro vyhledávání: '"il33"'
Autor:
Akihiro Ishii, Joseph A. Pathoulas, Omar MoustafaFathy Omar, Yingying Ge, Annie Y. Yao, Tressa Pantalena, Neeraj Singh, John Zhou, Wanxia He, Patrick Murphy, Riqiang Yan, Xiangyou Hu
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background The accumulation of β-amyloid (Aβ) peptides into insoluble plaques is an early pathological feature of Alzheimer’s disease (AD). BACE1 is the sole β-secretase for Aβ generation, making it an attractive therapeutic target for
Externí odkaz:
https://doaj.org/article/25be563e86234df7b0980f3ab6e5c547
Autor:
Putri Cahaya Situmorang, Syafruddin Ilyas, Rony Abdi Syahputra, Reka Mustika Sari, Alexander Patera Nugraha, Alek Ibrahim
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The prevalence of breast cancer among patients in Indonesia is significant. Indonesian individuals maintain the belief that cancer cannot be cured alone by pharmaceuticals and treatment; herbal remedies must be used in conjunction. Rhodomyrtus toment
Externí odkaz:
https://doaj.org/article/d8c4a2e6bdc541eca877ce7ec85aeacb
Autor:
Aimy Sebastian, Kelly A. Martin, Ivana Peran, Nicholas R. Hum, Nicole F. Leon, Beheshta Amiri, Stephen P. Wilson, Matthew A. Coleman, Elizabeth K. Wheeler, Stephen W. Byers, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the top five deadliest forms of cancer with very few treatment options. The 5-year survival rate for PDAC is 10% following diagnosis. Cadherin 11 (Cdh11), a cell-to-cell adhesion molecule, has been su
Externí odkaz:
https://doaj.org/article/50a6f40489714f8794e255c10b83ab8d
Autor:
Mukesh Verma, Divya Verma, Anand Santosh Sripada, Kapil Sirohi, Rangati Varma, Anita Sahu, Rafeul Alam
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundILC2s are capable of generating memory. The mechanism of memory induction and memory-driven effector function (trained immunity) in ILC2s is unknown.ObjectiveNFκB1 is preferentially expressed at a high level in ILC2s. We examined the role
Externí odkaz:
https://doaj.org/article/ee8bd1ebdb094e8a950332290a2e1c51
Autor:
Emma‐Jane Goode, Emma Marczylo
Publikováno v:
Clinical and Translational Allergy, Vol 13, Iss 6, Pp n/a-n/a (2023)
Abstract Allergic airway disease (AAD) is a collective term for respiratory disorders that can be exacerbated upon exposure to airborne allergens. The contribution of fungal allergens to AAD has become well established over recent years. We conducted
Externí odkaz:
https://doaj.org/article/5cf2cc7010f040c29192ec97670fccdd
Akademický článek
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PI3Kδ inhibition prevents IL33, ILC2s and inflammatory eosinophils in persistent airway inflammation
Autor:
Sorif Uddin, Augustin Amour, David J. Lewis, Chris D. Edwards, Matthew G. Williamson, Simon Hall, Lisa A. Lione, Edith M. Hessel
Publikováno v:
BMC Immunology, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Phosphoinositide-3-kinase-delta (PI3Kδ) inhibition is a promising therapeutic approach for inflammatory conditions due to its role in leucocyte proliferation, migration and activation. However, the effect of PI3Kδ inhibition on
Externí odkaz:
https://doaj.org/article/257ef4c6a3614587b0988d96a2e954dd
Akademický článek
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The Network of Pro-Inflammatory Factors CD147, DcR3, and IL33 in the Development of Kawasaki Disease
Publikováno v:
Journal of Inflammation Research, Vol Volume 14, Pp 6043-6053 (2021)
Yanqi Qi,* Jiawen Xu,* Zhe Lin,* Yijing Tao, Fenglei Zheng, Yujia Wang, Yameng Sun, Songling Fu, Wei Wang, Chunhong Xie, Yiying Zhang, Fangqi Gong Department of Cardiology, Children’s Hospital, Zhejiang University School of Medicine, Na
Externí odkaz:
https://doaj.org/article/c75fce8f2184429ca7325c8a43feb069
Autor:
Xin-Shu Liu, Zi-Yan Wu, Si Chen, Chan Zhao, Fei Gao, Ming-Hang Pei, Shan-Shan Jia, Yong-Zhe Li, Pei-Zeng Yang, Mei-Fen Zhang
Publikováno v:
International Journal of Ophthalmology, Vol 14, Iss 9, Pp 1315-1320 (2021)
AIM: To explore the association of single nucleotide polymorphisms (SNPs) in the IL33/IL1RL1 gene region with the susceptibility to Behcet's disease (BD) in a Chinese Han population. METHODS: A total of eight SNPs in the candidate gene region (rs1179
Externí odkaz:
https://doaj.org/article/57a1467bfa6846479711c11a0900d393