Zobrazeno 1 - 10
of 130
pro vyhledávání: '"il22"'
Autor:
Gwenaëlle Le Menn, Keela Pikkarainen, Daniela Mennerich, Dominika Miroszewska, Thomas Kietzmann, Zhi Chen
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionUbiquitin-specific proteases (USPs), a large subset of more than 50 deubiquitinase proteins, have recently emerged as promising targets in cancer. However, their role in immune cell regulation, particularly in T cell activation, different
Externí odkaz:
https://doaj.org/article/2abeeed136c54d528c613ce6ee85b70a
Publikováno v:
陆军军医大学学报, Vol 45, Iss 19, Pp 1995-2006 (2023)
Objective To investigate the effects of interleukin22 (IL22) in acute colitis induced by dextran sulfate sodium salt (DSS) in mice and its underlying mechanism. Methods Three IL22 knockout mice (IL22-/-) and 3 control mice (IL22+/+) of 8-week-old mal
Externí odkaz:
https://doaj.org/article/56f043d10b83446e9682e31077f6967b
Autor:
Bin Bao, Youyuan Wang, Pavl Boudreau, Xinyang Song, Meng Wu, Xi Chen, Izabel Patik, Ying Tang, Jodie Ouahed, Amit Ringel, Jared Barends, Chuan Wu, Emily Balskus, Jay Thiagarajah, Jian Liu, Michael R. Wessels, Wayne Isaac Lencer, Dennis L. Kasper, Dingding An, Bruce Harold Horwitz, Scott B. Snapper
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 2, Pp 101350- (2024)
Background & Aims: Gut bacterial sphingolipids, primarily produced by Bacteroidetes, have dual roles as bacterial virulence factors and regulators of the host mucosal immune system, including regulatory T cells and invariant natural killer T cells. P
Externí odkaz:
https://doaj.org/article/ebe59fd22bdd4d17a31e6bcf11e820ec
Akademický článek
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Akademický článek
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Autor:
Yan Wang, Qipeng Zhou, Lingzhu Chen, Lian Dong, Mingmei Xiong, Xiaohui Xie, Li Zhao, Jingyi Xu, Zeguang Zheng, Jian Wang, Wenju Lu
Publikováno v:
The Clinical Respiratory Journal, Vol 16, Iss 8, Pp 537-545 (2022)
Abstract The incidence of chronic obstructive pulmonary disease (COPD) is related to the interaction between environmental exposure and genetic factors. Far more than 15% of smokers eventually develop COPD. In addition to smoking, genetic susceptibil
Externí odkaz:
https://doaj.org/article/dd93605d03524958b8e33bac50b9167d
Autor:
Mohamed N. Abdelnabi, Manuel Flores Molina, Geneviève Soucy, Vincent Quoc-Huy Trinh, Nathalie Bédard, Sabrina Mazouz, Nathalie Jouvet, Jessica Dion, Sarah Tran, Marc Bilodeau, Jennifer L. Estall, Naglaa H. Shoukry
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 6, Pp 1269-1294 (2022)
Background & Aims: Nonalcoholic fatty liver disease (NAFLD) is a major health problem with complex pathogenesis. Although sex differences in NAFLD pathogenesis have been reported, the mechanisms underlying such differences remain understudied. Interl
Externí odkaz:
https://doaj.org/article/414b2226207c4b00976d3dd01d78d00a
Autor:
Hanieh Kolahdooz, Vahid Khori, Vahid Erfani-Moghadam, Fatemeh Livani, Saeed Mohammadi, Ali Memarian
Publikováno v:
Life, Vol 13, Iss 5, p 1076 (2023)
Psoriasis (PS) is characterized by hyperplasia of epidermis and infiltration of immune cells in the dermis. A negligible susceptibility of hypodermic permeation for local anti-inflammatory remedies is one of the major causes of medication failures. A
Externí odkaz:
https://doaj.org/article/ed81da785e0745b3a8225d359d3d63a5
Autor:
Sakhila Ghimire, Katharina U. Ederer, Elisabeth Meedt, Daniela Weber, Carina Matos, Andreas Hiergeist, Florian Zeman, Daniel Wolff, Matthias Edinger, Hendrik Poeck, Wolfgang Herr, André Gessner, Ernst Holler, Sigrid Bülow
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The role of IL-22 in adult patients undergoing allogeneic stem cell transplantation (SCT) is of major interest since animal studies showed a protective and regenerative effect of IL-22 in graft versus host disease (GvHD). However, no clinical data ex
Externí odkaz:
https://doaj.org/article/5bef20ac96274cb6b2abc1817d4572d3
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-21 (2020)
Abstract Background LncRNA LINC00662 is closely related to the occurrence and development of cancer. This study aims to explore the effect of LINC00662 on colon cancer tumor growth and metastasis and its molecular mechanism. Methods CCK8, colony form
Externí odkaz:
https://doaj.org/article/213d87f22af04c6489a30c203401b630