Zobrazeno 1 - 10
of 40 733
pro vyhledávání: '"il–2"'
Autor:
Faustina Adu, Ebenezer Aniakwaa-Bonsu, Samuel Badu Nyarko, Aikins Sarpong Obeng, Richmond Owusu Ateko, Akwasi Anyanful, Nicholas Ekow Thomford
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Hepatitis B virus (HBV) infection is a public health concern in resource limited settings like Ghana. Over the past decades, it is noted that the natural course of HBV in persons infected are taking a worse turn leading to liver c
Externí odkaz:
https://doaj.org/article/aac4b8181da14e938ec159826c689868
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Background Low-dose IL-2 (Ld-IL2) has shown favorable therapeutic effects in systemic lupus erythematosus (SLE) therapy. However, previous clinical trials reported an SLE Responder Index-4 (SRI-4) response rate of 65.52%-68%, with approximat
Externí odkaz:
https://doaj.org/article/90bef5d50c0e4e72b7019607f833b32a
Autor:
Shaoju Qian, Ruixue Li, Yeqing He, Hexi Wang, Danqiong Zhang, Aiping Sun, Lili Yu, Xiangfeng Song, Tiesuo Zhao, Zhiguo Chen, Zishan Yang
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Herpes simplex virus type 1 (HSV-1) is a major cause of viral encephalitis, genital mucosal infections, and neonatal infections. Lactococcus lactis (L. lactis) has been proven to be an effective vehicle for delivering protein anti
Externí odkaz:
https://doaj.org/article/f2e1ef0a4c7b476bac2d6b0e7381ac19
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafiq, Thomas S. Riad, Yun Hu, Ailing Huang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background Combining interleukin-2 (IL-2) with radiotherapy (RT) and immune checkpoint blockade (ICB) has emerged as a promising approach to address ICB resistance. However, conventional IL-2 cytokine therapy faces constraints owing to its b
Externí odkaz:
https://doaj.org/article/d5dfdad3aeaf4ef7a03ae6638ec04617
Publikováno v:
مجلة الكوفة الطبية, Vol 20, Iss 2 (2024)
Background: Alopecia areata (AA) is a condition that leads to the loss of hair in the part of the body due to the destruction of hair follicles, and causing patchy, non-scarring hair loss. The source of AA is unclear; however, there is much evidence
Externí odkaz:
https://doaj.org/article/1ee35195c4a8405c81cdfed3d65045ae
Autor:
Luise A. Roser, Charline Sommer, Samira Ortega Iannazzo, Christina Sakellariou, Zoe Waibler, Patricia Gogesch
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss sup1, Pp S38-S47 (2024)
Interleukin-2 (IL-2) was one of the first cytokines discovered and its central role in T cell function soon led to the notion that the cytokine could specifically activate immune cells to combat cancer cells. Recombinant human IL-2 (recIL-2) belonged
Externí odkaz:
https://doaj.org/article/30b72627c34e481289f3cb73c5bfb48d
Autor:
Charline Sommer, Vanessa Neuhaus, Patricia Gogesch, Thierry Flandre, Susann Dehmel, Katherina Sewald
Publikováno v:
Journal of Immunotoxicology, Vol 21, Iss sup1, Pp S48-S59 (2024)
The skin is the organ most often affected by adverse drug reactions. Although these cutaneous adverse drug reactions (CADRs) often are mild, they represent a major burden for patients. One of the drugs inducing CADRs is aldesleukin, a recombinant int
Externí odkaz:
https://doaj.org/article/d7da3c4f6c9e4169b6cac7a4e73a7e96
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesThis study aimed to evaluate the efficacy of low-dose interleukin (IL-2) treatment for bullous pemphigoid (BP) caused by anti-programmed cell death protein 1/ligand 1 (PD-1/PD-L1) inhibitors.MethodsLow-dose IL-2 treatment was standardized f
Externí odkaz:
https://doaj.org/article/50a5dad4aee9438e8e80eb8bc281aed2
Autor:
Guogang Xie, Hani Attar, Ayat Alrosan, Sally Mohammed Farghaly Abdelaliem, Amany Anwar Saeed Alabdullah, Mohanad Deif
Publikováno v:
PeerJ Computer Science, Vol 10, p e2455 (2024)
Searching for a reliable indicator of treatment response in sarcoidosis remains a challenge. The use of the soluble interleukin 2 receptor (sIL-2R) as a measure of disease activity has been proposed by researchers. A machine learning model was aimed
Externí odkaz:
https://doaj.org/article/d1d02aba838f42b4a410027c61f60d49
Autor:
Yuxin Chen, Meng Wang, Shuxin Huang, Lulu Han, Ying Cai, Xiaodi Xu, Shuwen Sun, Zhaokai Chen, Junze Chen, Jiatian Yu, Hongwei Du, Huizhong Li, Junnian Zheng, Bo Ma, Gang Wang
Publikováno v:
Pharmacological Research, Vol 210, Iss , Pp 107506- (2024)
Lack of biopsies after treatment, especially in solid tumors, restricts the understanding of chimeric antigen receptor (CAR)-T cells -related characteristic in vivo, thus hindering the development of strategies to improve CAR-T cells efficacy. Here,
Externí odkaz:
https://doaj.org/article/4238c5ac3c264d908351730d6829f867