Zobrazeno 1 - 10
of 675
pro vyhledávání: '"igf2bp3"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 12, Pp 1043-1056 (2024)
Abstract Retinoblastoma (RB) poses significant challenges in clinical management due to the emergence of resistance to conventional chemotherapeutic agents, particularly carboplatin (CBP). In this study, we investigated the molecular mechanisms under
Externí odkaz:
https://doaj.org/article/dd8da588963841b4802b8d595c182252
Autor:
Yuxin Huang, Wei Wang, Xinhao Fan, Xiaoqin Liu, Weiwei Liu, Zishuai Wang, Yixing Li, Yalan Yang, Zhonglin Tang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-20 (2024)
Abstract Background Myoblast fusion plays a crucial role in myogenesis. Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) functions as an RNA N 6-methyladenosine reader and exerts important roles in various biological processes. While our
Externí odkaz:
https://doaj.org/article/4b6c8ab6bcca49cf8090d4bd6ab3195e
Autor:
Jiang Yu, Yidan Gao, Fei Liu, Yuyu Zhang, Jianda Li, Luogang Ding, Sufang Ren, Jie Yang, Jian Jiao, Gong Feng, Zhi Chen, Wenbo Sun, Jiaqiang Wu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Animal and human health are seriously threatened by bacterial infections, which can lead to bacteremia and extremely high rates of morbidity and mortality. Recently, there have been reports indicating the involvement of exosomal c
Externí odkaz:
https://doaj.org/article/da36c109a7aa4032ad115c4522c1798d
Autor:
Wenjuan Zhang, Hui Liu, Changrong Ren, Kaiqian Zhang, Shuhan Zhang, Shifan Shi, Zhiyan Li, Jian Li
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The rapid expansion of the oncology field has revealed new insights into cell death processes, with a particular emphasis on the role of ferroptosis. Characterized by iron dependency and the accumulation of lipid peroxides and iron within ce
Externí odkaz:
https://doaj.org/article/7c3d821436af44c4b6354d05cb897ffb
Autor:
Yaobang Wang, Wuyue Song, Chao Feng, Shulin Wu, Zezu Qin, Tao Liu, Yu Ye, Rong Huang, Yuanliang Xie, Zhong Tang, Qiuyan Wang, Tianyu Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Muscle invasive bladder cancer (MIBC) is a life-threatening malignant tumor characterized by high metastasis rates, poor prognosis, and limited treatment options. Immune checkpoint inhibitors (ICIs) targeting PD-1 and PD-L1 repres
Externí odkaz:
https://doaj.org/article/66d5d50d0ee7434fa561093f7a3473c6
Autor:
Weiwei Jin, Yanru Yao, Yuhan Fu, Xiangxiang Lei, Wen Fu, Qiliang Lu, Xiangmin Tong, Qiuran Xu, Wei Su, Xiaoge Hu
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-16 (2024)
Abstract Background Pancreatic cancer (PC) is one of the most malignant cancers with highly aggressiveness and poor prognosis. N6-methyladenosine (m6A) have been indicated to be involved in PC development. Glucan Branching Enzyme 1 (GBE1) is mainly i
Externí odkaz:
https://doaj.org/article/a2d27816299a41f2973c831644c8b685
Autor:
Yuanxiang Lu, Jinghan Zhu, Yuxin Zhang, Wentao Li, Yixiao Xiong, Yunhui Fan, Yang Wu, Jianping Zhao, Changzhen Shang, Huifang Liang, Wanguang Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 46, Pp n/a-n/a (2024)
Abstract Acquired resistance remains a bottleneck for molecular‐targeted therapy in advanced hepatocellular carcinoma (HCC). Metabolic adaptation and epigenetic remodeling are recognized as hallmarks of cancer that may contribute to acquired resist
Externí odkaz:
https://doaj.org/article/91e77e00a6db4ef28e427cdc440e4547
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Background Lung squamous cell carcinoma (LUSC) is a type of lung cancer that develops in the squamous cells. It is known to be promoted by the activation of various signaling pathways and the dysregulation of key regulatory molecules. One su
Externí odkaz:
https://doaj.org/article/133c693d6250461592871ee59789bc3b
Publikováno v:
Thoracic Cancer, Vol 15, Iss 17, Pp 1357-1368 (2024)
Abstract Background Berberine (BBR), an isoquinoline alkaloid from Coptidis rhizoma, has been found to have powerful activities against various human malignancies, including breast cancer. However, the underlying antitumor mechanisms of BBR in breast
Externí odkaz:
https://doaj.org/article/53cf59590ce148e0ba67fc2e510f9f6f
Autor:
Yiran Liang, Fangzhou Ye, Dan Luo, Li Long, Yajie Wang, Yuhan Jin, Lei Wang, Yaming Li, Dianwen Han, Bing Chen, Wenjing Zhao, Lijuan Wang, Qifeng Yang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Breast cancer is the most common malignant tumor, and metastasis remains the major cause of poor prognosis. Glucose metabolic reprogramming is one of the prominent hallmarks in cancer, providing nutrients and energy to support dra
Externí odkaz:
https://doaj.org/article/fc63608af2e64d58b78a06ba25284c7a