Zobrazeno 1 - 10
of 673
pro vyhledávání: '"iei"'
Publikováno v:
Pediatria Polska, Vol 99, Iss 3, Pp 246-249 (2024)
Inborn errors of immunity (IEI) are genetically determined disorders which present clinically as increased susceptibility to infectious, autoinflammatory, or autoimmune diseases, potentially leading to fatal outcomes. Some doctors omit collecting fam
Externí odkaz:
https://doaj.org/article/af0e879407494b46b2d828a724adf4eb
Autor:
Engy A. Chohayeb, Sohilla Lotfy, Rabab E. El Hawary, Safa S. Meshaal, Iman A. Mansour, Nermeen M. Galal, Aisha M. Elmarsafy
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Purine nucleoside phosphorylase (PNP) deficiency is a rare, autosomal recessive, inborn error of immunity. It is characterized by progressive immune abnormalities ranging from severe combined immunodeficiency (SCID) to combined im
Externí odkaz:
https://doaj.org/article/ae60fe2c53c04b559010ef2cb38019f1
fSCIG 10% in pediatric primary immunodeficiency diseases: a European post-authorization safety study
Autor:
Peter Čižnár, Marion Roderick, Helen Schneiderova, Miloš Jeseňák, Gergely Kriván, Nicholas Brodszki, Stephen Jolles, Charles Atisso, Katharina Fielhauer, Shumyla Saeed-Khawaja, Barbara McCoy, Leman Yel
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-9 (2024)
Abstract Background The safety, tolerability, and immunogenicity of hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10% (dual-vial unit of human immunoglobulin 10% and recombinant human hyaluronidase [rHuPH20]) were assessed in children
Externí odkaz:
https://doaj.org/article/b11f26ec3f924caba62435caad1fce8a
Autor:
Lucía del Pino Molina, Keren Reche Yebra, Yolanda Soto Serrano, Álvaro Clemente Bernal, Carmen L. Avendaño-Monje, J. Gonzalo Ocejo-Vinyals, Rebeca Rodríguez Pena, Eduardo López Granados
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe use of next-generation sequencing in inborn errors of immunity (IEI) has considerably increased the identification of novel gene variants, many of which are identified in patients without the described clinical phenotype or with variant
Externí odkaz:
https://doaj.org/article/57b54d68b88b426487bdc3bb0eda2b84
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/868b897f7b7c4a31bfa2672242d6afb7
Autor:
Vassilios Lougaris, Federico Le Piane, Caterina Cancrini, Francesca Conti, Alberto Tommasini, Raffaele Badolato, Antonino Trizzino, Marco Zecca, Antonio De Rosa, Federica Barzaghi, Claudio Pignata
Publikováno v:
Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-11 (2024)
Abstract Activated phosphoinositide 3-kinase (PI3Kδ) Syndrome (APDS) is an inborn error of immunity (IEI) with a variable clinical presentation, characterized by infection susceptibility and immune dysregulation that may overlaps with other Primary
Externí odkaz:
https://doaj.org/article/c3a720bfdd824b72a325d875a42d7813
Autor:
Abdulrahman Abdulaziz Abdullah, Wafaa Mostafa Abd-El-Gawad, Sobhi Mostafa AboSerea, Fatma AbdelShakor Ali, Saima Ali
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Objectives Many associations have recently recommended early integration of oncology and palliative care for more standard cancer care and better quality of life. We aimed to create a questionnaire to assess the opinion of medical oncologist
Externí odkaz:
https://doaj.org/article/f492212379384c0eb3b71494fd417cf4
Publikováno v:
Pediatric Discovery, Vol 2, Iss 3, Pp n/a-n/a (2024)
Abstract Primary immunodeficiency diseases (PIDs) present a heterogeneous group of diseases with aberrant immune response caused by monogenic mutations. Due to the immune dysfunction and dysregulation, PIDs have a wide clinical spectrum such as infec
Externí odkaz:
https://doaj.org/article/6bc2ca2712c44fccb7a54fb23ade5ad0
Autor:
Katarzyna Napiórkowska-Baran, Jarosław Biliński, Małgorzata Pujanek, Paweł Hałakuc, Antoni Pietryga, Bartłomiej Szymczak, Aleksander Deptuła, Tomasz Rosada, Zbigniew Bartuzi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The gut microbiota serves a crucial role in the development of host immunity. Immunocompromised patients are particularly vulnerable to dysbiosis not only by virtue of a defect in the immune system but also due to increased susceptibility to infectio
Externí odkaz:
https://doaj.org/article/fc700d0cc5364d6f84620496447432b6
Autor:
Adil Karim, Rashi Garg, Biman Saikia, Abha Tiwari, Smrity Sahu, Mehak Malhotra, Ranjana W. Minz, Amit Rawat, Surjit Singh, Deepti Suri
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPatients with loss of function signal transducer and activator of transcription 3-related Hyper IgE Syndrome (LOF STAT3 HIES) present with recurrent staphylococcal skin and pulmonary infections along with the elevated serum IgE levels, ecze
Externí odkaz:
https://doaj.org/article/74133cf61e324bbfa36cdecfba5e5655