Zobrazeno 1 - 10
of 328
pro vyhledávání: '"idrs"'
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 10, Pp 4299-4307 (2024)
Introduction Noncommunicable diseases are a leading cause of death worldwide, claiming 41 million lives annually. Notably, type 2 diabetes not only presents well-known complications but also increases the risk of cardiovascular disease silently. Furt
Externí odkaz:
https://doaj.org/article/6667f604a98345afa6456d013d235780
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-18 (2024)
ABSTRACTProtein aggregation, a consequence of misfolding and impaired proteostasis, can lead to cellular malfunctions such as various proteinopathies. The mechanisms protecting proteins from aggregation in complex cellular environments have long been
Externí odkaz:
https://doaj.org/article/636a7a351a044219b211efb88ebe307a
Autor:
Yogita G Bavaskar
Publikováno v:
MGM Journal of Medical Sciences, Vol 11, Iss 3, Pp 460-466 (2024)
Background: Diabetes, once primarily associated with old age, is increasingly prevalent among young adults. The Indian Diabetes Risk Score (IDRS) employs four parameters—age, waist circumference, family history of diabetes, and physical activity—
Externí odkaz:
https://doaj.org/article/4d71ce02d9aa4cf6bfca0a4db3a68c8c
Autor:
Stefano Magnati, Enrico Bracco
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 158-167 (2024)
In the last few decades, the traditional paradigm of teleonomy, in which the amino acid sequence of a protein is tightly associated with its structure and, in turn, with its function, has been partially undermined. The idea of a protein as a two-stat
Externí odkaz:
https://doaj.org/article/0b087316a3174ade84b0ecdb5a46eb10
Autor:
Marco Schiavina, Lorenzo Bracaglia, Tessa Bolognesi, Maria Anna Rodella, Giuseppe Tagliaferro, Angela Sofia Tino, Roberta Pierattelli, Isabella C. Felli
Publikováno v:
Journal of Magnetic Resonance Open, Vol 18, Iss , Pp 100143- (2024)
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) of complex multi-domain proteins are now identified as a trend topic by the scientific community. NMR constitutes a unique investigation tool to access atom resolved
Externí odkaz:
https://doaj.org/article/128b4135755546d79da5e64a2f8be140
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Intrinsically disordered regions (IDRs) are widely distributed in proteins and related to many important biological functions. Accurately identifying IDRs is of great significance for protein structure and function analysis. Becau
Externí odkaz:
https://doaj.org/article/03754250f9fa47a7bf7d3a64fc9668f8
Autor:
Ling Cai, Gang Greg Wang
Publikováno v:
Nucleus, Vol 14, Iss 1 (2023)
ABSTRACTThe establishment, maintenance and dynamic regulation of three-dimensional (3D) chromatin structures provide an important means for partitioning of genome into functionally distinctive domains, which helps to define specialized gene expressio
Externí odkaz:
https://doaj.org/article/e540dd65ec1a4afcbcc8a175f94d48c2
Publikováno v:
Indian Journal of Community Medicine, Vol 49, Iss 7, Pp 34-34 (2024)
Background: Non-communicable diseases (NCD) kill 41 million people each year which accounts to 74% of all deaths globally. India ranks second with a diabetes population of 69.2 million and may rise to 123.5 million by 2040. Early detection of diabete
Externí odkaz:
https://doaj.org/article/4a99887a2b374f209fc30f178e23c687
Autor:
Vijayan Veena, Mundada Vinod D.
Publikováno v:
Indian Journal of Community Medicine, Vol 49, Iss 7, Pp 57-57 (2024)
Background: Diabetes mellitus is one of the major public health problems that affects all age groups. Usually, medical students have sedentary lifestyle owing to academic requirements and there are only limited studies on diabetes screening have been
Externí odkaz:
https://doaj.org/article/a349f22eea60463e8bc9f53534fd67aa
Autor:
Jianxing Song
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 500 (2024)
Adenosine triphosphate (ATP) acts as the universal energy currency that drives various biological processes, while nucleic acids function to store and transmit genetic information for all living organisms. Liquid–liquid phase separation (LLPS) repr
Externí odkaz:
https://doaj.org/article/a562e94fb6c44b899af73ff509e9f6af