Zobrazeno 1 - 10
of 79
pro vyhledávání: '"iPSCs, induced pluripotent stem cells"'
Autor:
Chie Naito, Karis Kosar, Eriko Kishimoto, Loren Pena, Yilun Huang, Kaili Hao, Anas Bernieh, Jennifer Kasten, Chet Villa, Priya Kishnani, Bali Deeksha, Mingxia Gu, Akihiro Asai
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 39, Iss , Pp 101069- (2024)
Background: Glycogen Storage disease type 4 (GSD4), a rare disease caused by glycogen branching enzyme 1 (GBE1) deficiency, affects multiple organ systems including the muscles, liver, heart, and central nervous system. Here we report a GSD4 patient,
Externí odkaz:
https://doaj.org/article/60fc31d9dbb348cd85f5493e6acaff31
Autor:
Niraj Patel, Vincent Ouellet, François Paquet-Mercier, Nizar Chetoui, Erik Bélanger, Marie-Eve Paquet, Antoine G. Godin, Pierre Marquet
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionHuman induced pluripotent stem cells (iPSCs), with their ability to generate human neural cells (astrocytes and neurons) from patients, hold great promise for understanding the pathophysiology of major neuropsychiatric diseases such as sc
Externí odkaz:
https://doaj.org/article/d75bcabef3a94510a2a7462309492018
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Neurodegenerative diseases (NDDs) are disorders in which neurons are lost owing to various factors, resulting in a series of dysfunctions. Their rising prevalence and irreversibility have brought physical pain to patients and economic pressure to bot
Externí odkaz:
https://doaj.org/article/131502978c2c4d6da4b76c283e11fea1
Akademický článek
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
In developed countries, the aging of the population and the associated increase in age-related diseases are causing major unresolved medical, social, and environmental matters. Therefore, research on aging has become one of the most important and urg
Externí odkaz:
https://doaj.org/article/962c41754c1f4824874cb5f73c37f174
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD) is an aging-dependent neurodegenerative disease that impairs cognitive function. Although the main pathologies of AD are the aggregation of amyloid-beta (Aβ) and phosphorylated Tau protein, the mechanisms that lead to thes
Externí odkaz:
https://doaj.org/article/9e83c20e667e44e1a12dd499e9e741f4
Autor:
Florencia D. Haase, Bronte Coorey, Lisa Riley, Laurence C. Cantrill, Patrick P. L. Tam, Wendy A. Gold
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder, mostly caused by mutations in MECP2. The disorder mainly affects girls and it is associated with severe cognitive and physical disabilities. Modeling RTT in neural and glial cell culture
Externí odkaz:
https://doaj.org/article/06e4d5b016054a928b140c8c81135b09
Autor:
Verónica Uribe-Etxebarria, Jose Ramon Pineda, Patricia García-Gallastegi, Alice Agliano, Fernando Unda, Gaskon Ibarretxe
The Dental Pulp of permanent human teeth is home to stem cells with remarkable multilineage differentiation ability: human Dental Pulp Stem Cells (DPSCs). These cells display a very notorious expression of pluripotency core factors, and the ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91227ba0d372502c234fd0bc01357b8
http://hdl.handle.net/10810/60962
http://hdl.handle.net/10810/60962
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1697-1707 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Small intestine in vitro models play a crucial role in drug transport research. Although conventional 2D cell culture models, such as Caco-2 monolayer, possess many advantages, they should be interpreted with caution because they have relatively poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd5440f02c300c8abab983b55b9cdda
https://doi.org/10.1016/j.apsb.2020.12.002
https://doi.org/10.1016/j.apsb.2020.12.002
Autor:
A. Cota-Coronado, O.R. Hernández-Pérez, Néstor F. Díaz, Pavel H. Lugo-Fabres, N. Emmanuel Díaz-Martínez, Valeria Valadez-Barba, Eduardo Padilla-Camberos
Publikováno v:
Regenerative Therapy, Vol 15, Iss, Pp 332-339 (2020)
Regenerative Therapy
Regenerative Therapy
Neurodegenerative disorders such as Parkinson's and Alzheimer's disease, are fundamental health concerns all around the world. The development of novel treatments and new techniques to address these disorders, are being actively studied by researcher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5533df458e5d5b5603371b246a30631c
http://www.sciencedirect.com/science/article/pii/S2352320420300894
http://www.sciencedirect.com/science/article/pii/S2352320420300894