Zobrazeno 1 - 10
of 55
pro vyhledávání: '"iPSC, induced pluripotent stem cells"'
Autor:
Bita Massih, Alexander Veh, Maren Schenke, Simon Mungwa, Bettina Seeger, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Peter Reinhardt, Jared Sterneckert, Andreas Hermann, Michael Sendtner, Patrick Lüningschrör
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The signals that coordinate and control movement in vertebrates are transmitted from motoneurons (MNs) to their target muscle cells at neuromuscular junctions (NMJs). Human NMJs display unique structural and physiological features, which make them vu
Externí odkaz:
https://doaj.org/article/3abe4a86364943e08d4a264b7f13ba1a
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders characterized by impaired social interactions as well as the presentation of restrictive and repetitive behaviors. ASD is highly heritable but genetically heter
Externí odkaz:
https://doaj.org/article/785a10af9f2b4448ab0087a2833d2fd6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Treatment of cancer with allogeneic natural killer (NK) cell therapies has seen rapid development, especially use against hematologic malignancies. Clinical trials of NK cell-based adoptive transfer to treat relapsed or refractory malignancies have u
Externí odkaz:
https://doaj.org/article/038525745b4e4edb9096807037080a39
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Inflammation is a shared hallmark between amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). For long, studies were conducted on tissues of post-mortem patients and neuroinflammation was thought to be only bystander result of the
Externí odkaz:
https://doaj.org/article/61477fff952f4ac594d64af6eb7b42c4
Autor:
Anbin Chen, Cecilie Katrin Kristiansen, Yu Hong, Atefeh Kianian, Evandro Fei Fang, Gareth John Sullivan, Jian Wang, Xingang Li, Laurence A. Bindoff, Kristina Xiao Liang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mitophagy specifically recognizes and removes damaged or superfluous mitochondria to maintain mitochondrial homeostasis and proper neuronal function. Defective mitophagy and the resulting accumulation of damaged mitochondria occur in several neurodeg
Externí odkaz:
https://doaj.org/article/2a4dff71cdaf47aab7ed7d5d5242e062
Autor:
Kenji Yamatoya, Yuya Nagai, Naozumi Teramoto, Woojin Kang, Kenji Miyado, Kazuya Nakata, Tohru Yagi, Yoshitaka Miyamoto
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 19, Iss, Pp 58-68 (2022)
Regenerative Therapy, Vol 19, Iss, Pp 58-68 (2022)
The effective use of human-derived cells that are difficult to freeze, such as parenchymal cells and differentiated cells from stem cells, is crucial. A stable supply of damage-sensitive cells, such as differentiated neuronal cells, neurons, and glia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05e5e2da866000a81553e84ac48fa62
https://doi.org/10.1016/j.reth.2021.12.007
https://doi.org/10.1016/j.reth.2021.12.007
Autor:
Andy Y. Liu, Rodrigo Aguayo-Ortiz, Guadalupe Guerrero-Serna, Nulang Wang, Muriel G. Blin, Daniel R. Goldstein, L. Michel Espinoza-Fonseca
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss, Pp 380-384 (2022)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Phospholamban (PLN) and Sarcolipin (SLN) are homologous membrane proteins that belong to the family of proteins that regulate the activity of the cardiac calcium pump (sarcoplasmic reticulum Ca2+-ATPase, SERCA). PLN and SLN share highly conserved leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede8d8d93f1d7fd73ccf973b54b6261e
http://www.sciencedirect.com/science/article/pii/S2001037021005407
http://www.sciencedirect.com/science/article/pii/S2001037021005407
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018
Autor:
Margarita Gerou, Benjamin A. Hall, Scott P. Allen, Kathrin Meyer, Pamela J. Shaw, Ryan Woof, Jessica Allsop, Stephen J. Kolb
Publikováno v:
Neurobiology of Aging
Highlights • Aging affects the metabolic profile of fibroblasts derived from ALS cases • Increased NADH metabolism with age is observed in the presence of a specific set of catabolic energy substrates in healthy individuals • Reduced NADH metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa322bad33369b41380c3947538e1343
http://europepmc.org/articles/PMC8346650
http://europepmc.org/articles/PMC8346650
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