Zobrazeno 1 - 10
of 171
pro vyhledávání: '"iPSC, Induced pluripotent stem cell"'
Publikováno v:
Cells, Vol 13, Iss 23, p 1976 (2024)
Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system capable of killing virus-infected cells and/or cancer cells. The commonly used NK cells for therapeutic applications include primary NK cells and immortalized NK cell lin
Externí odkaz:
https://doaj.org/article/cac7deaa6dd14fc7b5eb1d80a357bdce
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Chimeric antigen receptor (CAR) T cell therapy has effectively complemented the treatment of advanced relapsed and refractory hematological cancers. The remarkable achievements of CD19- and BCMA-CAR T therapies have raised high expectations within th
Externí odkaz:
https://doaj.org/article/f04ddcfc676e402e870c7f56755056a4
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Neurodevelopmental disorders (NDDs) include a broad spectrum of pathological conditions that affect >4% of children worldwide, share common features and present a variegated genetic origin. They include clinically defined diseases, such as autism spe
Externí odkaz:
https://doaj.org/article/8629bf3dd9634fffb4c3993a57b0fdc2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Blood has an important role in the healthcare system, particularly in blood transfusions and immunotherapy. However, the occurrence of outbreaks of infectious diseases worldwide and seasonal fluctuations, blood shortages are becoming a major challeng
Externí odkaz:
https://doaj.org/article/1acdd841b45647089d131fc247f510df
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Protocols to differentiate human pluripotent stem cells have advanced in terms of cell type specificity and tissue-level complexity over the past 2 decades, which has facilitated human disease modeling in the most relevant cell types. The ability to
Externí odkaz:
https://doaj.org/article/dc620c65371443918ec4822f785976cf
Autor:
James Williams, Chloe Hurling, Sabrina Munir, Peter Harley, Carolina Barcellos Machado, Ana-Maria Cujba, Mario Alvarez-Fallas, Davide Danovi, Ivo Lieberam, Rocio Sancho, Philip Beales, Fiona M. Watt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Bardet-Biedl syndrome (BBS) is a ciliopathy with pleiotropic effects on multiple tissues, including the kidney. Here we have compared renal differentiation of iPS cells from healthy and BBS donors. High content image analysis of WT1-expressing kidney
Externí odkaz:
https://doaj.org/article/d171a7913adc46668842c8c82971940f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/27e6ec48b38647148f16fe9a4cfe8a0a
Autor:
Landon J. Rohowetz, Peter Koulen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The eyes are relatively immune privileged organs, making them ideal targets for stem cell therapy. Researchers have recently developed and described straightforward protocols for differentiating embryonic and induced pluripotent stem cells into retin
Externí odkaz:
https://doaj.org/article/ddb4444ac3184f2bbffac11a24f7e222
Autor:
A. B. Carvalho, Keyla Cristiny da Silva Coutinho, Raiana Andrade Quintanilha Barbosa, Dilza Balteiro Pereira de Campos, Isabela de Carvalho Leitão, R. S. Pinto, D. Silva Dos Santos, Bruna Farjun, Dayana da Silva De Araújo, Fernanda Cristina Paccola Mesquita, G. Monnerat-Cahli, E. H. Medei, Tais Hanae Kasai-Brunswick, A. C. Campos De Carvalho
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Human pluripotent stem cells (PSC) have been used for disease modelling, after differentiation into the desired cell type. Electrophysiologic properties of cardiomyocytes derived from pluripotent stem cells are extensively used to model cardiac arrhy
Externí odkaz:
https://doaj.org/article/f7783f6dc8cd403283ccf37120d7bca7
Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/ef29f3bfd4614b8a8045732519fd2052