Zobrazeno 1 - 10
of 1 055
pro vyhledávání: '"iPS cell"'
Autor:
Shohei Kitahata, Michiko Mandai, Hinako Ichikawa, Yuji Tanaka, Toshika Senba, Keisuke Kajita, Sunao Sugita, Kazuaki Kadonosono, Masayo Takahashi
Publikováno v:
Regenerative Therapy, Vol 25, Iss , Pp 238-249 (2024)
Introduction: The retinal pigment epithelium (RPE) plays essential roles in maintaining retinal functions as well as choroidal capillaries and can lead to visual disorders if dysfunctional. Transplantation of human-induced pluripotent stem cell-deriv
Externí odkaz:
https://doaj.org/article/07ab9e110ef742229cde3e1c477d1da7
Autor:
Tatsuya Inui, Yusei Uraya, Jumpei Yokota, Tomoki Yamashita, Kanae Kawai, Kentaro Okada, Yukiko Ueyama-Toba, Hiroyuki Mizuguchi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Human induced pluripotent stem (iPS) cell-derived enterocyte-like cells (ELCs) are expected to be useful for evaluating the intestinal absorption and metabolism of orally administered drugs. However, it is difficult to generate la
Externí odkaz:
https://doaj.org/article/0d9f9919464a474da5281380fc90759e
Autor:
Ryohei Takada, Michihiro Toritsuka, Takahira Yamauchi, Rio Ishida, Yoshinori Kayashima, Yuki Nishi, Mitsuru Ishikawa, Kazuhiko Yamamuro, Minobu Ikehara, Takashi Komori, Yuki Noriyama, Kohei Kamikawa, Yasuhiko Saito, Hideyuki Okano, Manabu Makinodan
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background A growing body of evidence suggests that immune dysfunction and inflammation in the peripheral tissues as well as the central nervous system are associated with the neurodevelopmental deficits observed in autism spectrum disorder
Externí odkaz:
https://doaj.org/article/d4371887269c4db7bf95d1b63ee05347
Autor:
Yasuteru Inoue, Yingxue Ren, Shuwen Zhang, Michael Bamkole, Naeyma N. Islam, Manikandan Selvaraj, Wenyan Lu, Thomas R. Caulfield, Yonghe Li, Takahisa Kanekiyo
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The maturation of brain microvascular endothelial cells leads to the formation of a tightly sealed monolayer, known as the blood–brain barrier (BBB). The BBB damage is associated with the pathogenesis of age-related neurodegenerative diseases inclu
Externí odkaz:
https://doaj.org/article/044332bc5f914607b440f788e2c9c05e
Autor:
Xiaolan Lin, Tian Guan, Yun Li, Yanchun Lin, Guowei Huang, Yan Lin, Pingnan Sun, Congzhu Li, Jiang Gu, Haoyu Zeng, Changchun Ma
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe clinical efficacy of CAR-NK cells against CD19-expressing blood cancers has been demonstrated, and they have shown potential for treating solid tumors as well. However, the efficacy of CAR-NK cells for treating human oral tongue squam
Externí odkaz:
https://doaj.org/article/2f4acbd60e284a1682c5172ca3fe7a7d
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
SPG7 is the most common form of autosomal recessive hereditary spastic paraplegia (HSP). There is a lack of HSP-SPG7 human neuronal models to understand the disease mechanism and identify new drug treatments. We generated a human neuronal model of HS
Externí odkaz:
https://doaj.org/article/57be7d5bf81b48b8b7b29c84929cba12
Autor:
Hao Wu, Jovial Niyogisubizo, Keliang Zhao, Jintao Meng, Wenhui Xi, Hongchang Li, Yi Pan, Yanjie Wei
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16028 (2023)
The automatic detection of cells in microscopy image sequences is a significant task in biomedical research. However, routine microscopy images with cells, which are taken during the process whereby constant division and differentiation occur, are no
Externí odkaz:
https://doaj.org/article/1d3b8d4966ea4addbc9fdc73335ac796
Akademický článek
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Akademický článek
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Publikováno v:
North American Spine Society Journal, Vol 13, Iss , Pp 100184- (2023)
Spinal cord injury (SCI) has been considered to cause sudden, irreversible loss of function in patients. However, developments in stem cell biology and regenerative medicine are changing this conventional notion. Here we reviewed the overview of rege
Externí odkaz:
https://doaj.org/article/28a69005e56c45fc86d16f699253247d