Zobrazeno 1 - 10
of 63
pro vyhledávání: '"iPS, induced pluripotent stem"'
Autor:
Huajin Li, Wenting Xu, Sijia Xiang, Leiting Tao, Wen Fu, Jinhui Liu, Wenbin Liu, Yamei Xiao, Liangyue Peng
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Pluripotency is a transient state in early embryos, which is regulated by an interconnected network of pluripotency-related genes. The pluripotent state itself seems to be highly dynamic, which leads to significant differences in the description of i
Externí odkaz:
https://doaj.org/article/4e6da929557948e599dc981c05cb2dcf
Autor:
Keisuke Sekine
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Recent progress in the field of organoid-based cell culture systems has enabled the use of patient-derived cells in conditions that resemble those in cancer tissue, which are better than two-dimensional (2D) cultured cell lines. In particular, organo
Externí odkaz:
https://doaj.org/article/7c56f7a611d3464ba590446a27eeaa59
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
A mechanistic understanding of the genetic basis of complex diseases such as diabetes mellitus remain elusive due in large part to the activity of genetic disease modifiers that impact the penetrance and/or presentation of disease phenotypes. In the
Externí odkaz:
https://doaj.org/article/a0836c554b234d3186794768e0c6f96c
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Induced pluripotent stem cell-derived organoids offer an unprecedented access to complex human tissues that recapitulate features of architecture, composition and function of in vivo organs. In the context of Parkinson's Disease (PD), human midbrain
Externí odkaz:
https://doaj.org/article/25710e4f42504e1a92f2f81fe61a5528
Autor:
Antonio P. Beltrami, Gaia Spinetti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 5 (2018)
Externí odkaz:
https://doaj.org/article/d5f59571928a4b7da2b0afc6f09afe09
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 16, Iss, Pp 63-72 (2021)
Regenerative Therapy, Vol 16, Iss, Pp 63-72 (2021)
Due to traffic accidents, injuries, burns, congenital malformations and other reasons, a large number of patients with tissue or organ defects need urgent treatment every year. The shortage of donors, graft rejection and other problems cause a defici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c113b43a74ae9775806d3e3fc623b5
http://europepmc.org/articles/PMC7868584
http://europepmc.org/articles/PMC7868584
Autor:
Huajin Li, Wenting Xu, Sijia Xiang, Leiting Tao, Wen Fu, Jinhui Liu, Wenbin Liu, Yamei Xiao, Liangyue Peng
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Pluripotency is a transient state in early embryos, which is regulated by an interconnected network of pluripotency-related genes. The pluripotent state itself seems to be highly dynamic, which leads to significant differences in the description of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8432de9abad07a7759e9a457e0d1a262
https://pubmed.ncbi.nlm.nih.gov/35222539
https://pubmed.ncbi.nlm.nih.gov/35222539
Autor:
I. Wayan Sumardika, Hidekazu Iioka, Ken Saito, Satoshi Maruyama, Masakiyo Sakaguchi, Eisaku Kondo
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1121-1132 (2019)
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 12, Pp 1121-1132 (2019)
Pancreatic invasive ductal adenocarcinoma (PDAC) is a representative intractable malignancy under the current cancer therapies, and is considered a scirrhous carcinoma because it develops dense stroma. Both PODXL1, a member of CD34 family molecules,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36cc890e92c9be87fd4184f2ce6be4f
https://ousar.lib.okayama-u.ac.jp/57594
https://ousar.lib.okayama-u.ac.jp/57594
Autor:
Masato Fujioka, Tatsuo Matsunaga, Tsubasa Saeki, Kaoru Ogawa, Hideyuki Okano, Makoto Hosoya, Chika Saegusa
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 10, Iss, Pp 54-63 (2019)
Regenerative Therapy, Vol 10, Iss, Pp 54-63 (2019)
Introduction Pendred syndrome is an autosomal-recessive disease characterized by congenital hearing loss and thyroid goiter. Previously, cell stress susceptibilities were shown to increase in patient-derived cells with intracellular aggregation using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33734df0177fea1b7f1d49ebc6e79cda
https://doi.org/10.1016/j.reth.2018.11.001
https://doi.org/10.1016/j.reth.2018.11.001
Publikováno v:
The Journal of Biological Chemistry
In recent years, enterovirus D68 (EV-D68) has advanced from a rarely detected respiratory virus to a widespread pathogen responsible for increasing rates of severe respiratory illness and acute flaccid myelitis (AFM) in children worldwide. In this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3177e21b6906a8416481880e71cb5de7
https://pubmed.ncbi.nlm.nih.gov/34237885
https://pubmed.ncbi.nlm.nih.gov/34237885