Zobrazeno 1 - 8
of 8
pro vyhledávání: '"iBAT, interscapular brown adipose tissue"'
Autor:
Laurie L. Baggio, Phillip E. Scherer, Xiemin Cao, Elodie M. Varin, Daniel J. Drucker, Kirandeep Kaur, Jonathan E. Campbell, Jennifer H. Stern, Jacqueline L. Beaudry, Erin E. Mulvihill
Publikováno v:
Molecular Metabolism, Vol 22, Iss, Pp 37-48 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f68bfd4c4069c7e184a9d2d3ab4c2a
http://www.sciencedirect.com/science/article/pii/S2212877819300419
http://www.sciencedirect.com/science/article/pii/S2212877819300419
Autor:
Esther Paulo, Catherine E. Gleason, Yixuan Wu, Ajay Chawla, Seunghwan Lee, Biao Wang, David A. Pearce, Prasanna K.R. Allu, Gavin Situ, Ambre M. Bertholet, Bidisha Saha
Publikováno v:
The Journal of Biological Chemistry
Nonshivering thermogenesis is essential for mammals to maintain body temperature. According to the canonical view, temperature is sensed by cutaneous thermoreceptors and nerve impulses transmitted to the hypothalamus, which generates sympathetic sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf5e598fa616663a0fba4245500757e
http://europepmc.org/articles/PMC8121962
http://europepmc.org/articles/PMC8121962
Autor:
Matthew J. Watt, Brian J. Oldfield, Andrew M. Allen, Sonika Tyagi, Aneta Stefanidis, Nicole M. Wiedmann
Publikováno v:
Molecular Metabolism, Vol 11, Iss, Pp 47-58 (2018)
Molecular Metabolism
Molecular Metabolism
Objective The potential for brown adipose tissue (BAT) to be targeted as a therapeutic option to combat obesity has been heightened by the discovery of a brown–like form of inducible “beige” adipose tissue in white fat which has overlapping str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ca3266ec5077ca7b51a5329fbb1309
https://doi.org/10.1016/j.molmet.2018.01.024
https://doi.org/10.1016/j.molmet.2018.01.024
Autor:
Astrid L. Basse, Julia Peics, Iuliia Karavaeva, Karen Nørgaard Nielsen, Tao Ma, Jonas T. Treebak, Sabina Chubanava, Zachary Gerhart-Hines, Oksana Dmytriyeva, Morten Dall
Publikováno v:
Molecular Metabolism
Nielsen, K N, Peics, J, Ma, T, Karavaeva, I, Dall, M, Chubanava, S, Basse, A L, Dmytriyeva, O, Treebak, J T & Gerhart-Hines, Z 2018, ' NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity ', Molecular Metabolism, vol. 11, pp. 178-188 . https://doi.org/10.1016/j.molmet.2018.02.014
Molecular Metabolism, Vol 11, Iss, Pp 178-188 (2018)
Nielsen, K N, Peics, J, Ma, T, Karavaeva, I, Dall, M, Chubanava, S, Basse, A L, Dmytriyeva, O, Treebak, J T & Gerhart-Hines, Z 2018, ' NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity ', Molecular Metabolism, vol. 11, pp. 178-188 . https://doi.org/10.1016/j.molmet.2018.02.014
Molecular Metabolism, Vol 11, Iss, Pp 178-188 (2018)
Objective The ability of adipose tissue to expand and contract in response to fluctuations in nutrient availability is essential for the maintenance of whole-body metabolic homeostasis. Given the nutrient scarcity that mammals faced for millions of y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f736a92e4b1fe58e43399f29f9ef799
http://europepmc.org/articles/PMC6001355
http://europepmc.org/articles/PMC6001355
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 9, Iss, Pp 192-198 (2018)
Molecular Metabolism, Vol 9, Iss, Pp 192-198 (2018)
Objective Activation of thermogenesis in brown adipose tissue (BAT) and the ability to increase uncoupling protein 1 (UCP1) levels and mitochondrial biogenesis in white fat (termed ‘browning’), has great therapeutic potential to treat obesity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf4c6e369f9bb0a2692c57390c55d70
http://europepmc.org/articles/PMC5870104
http://europepmc.org/articles/PMC5870104
Autor:
Raffaele Teperino
Publikováno v:
Molecular Metabolism
Mol. Metab. 6, 1079-1080 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1079-1080 (2017)
Mol. Metab. 6, 1079-1080 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1079-1080 (2017)
Objective Maternal and environmental factors control the epigenetic fetal programming of the embryo, thereby defining the susceptibility for metabolic or endocrine disorders in the offspring. Pharmacological interventions required as a consequence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ac4b40cb2d2b6696510108f5474839
https://pubmed.ncbi.nlm.nih.gov/29031714
https://pubmed.ncbi.nlm.nih.gov/29031714
Autor:
Annie Ogasawara, James Ziai, Junichiro Sonoda, Joshua C. Chang, Victor Nunez, Minh Thai, Jose Zavala-Solorio, Ganesh Kolumam, Robert J. Newman, Lance Kates, Khanhky Phamluong, Sean Flanagan, Søren Warming, Mark Z. Chen, Xiaobo Bai
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1454-1467 (2017)
Molecular Metabolism, Vol 6, Iss 11, Pp 1454-1467 (2017)
Objective Fibroblast Growth Factor 21 (FGF21) is a potent stimulator of brown fat thermogenesis that improves insulin sensitivity, ameliorates hepatosteatosis, and induces weight loss by engaging the receptor complex comprised of Fibroblast Growth Fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01331d06bde68c629b66d95dda9d735
https://pubmed.ncbi.nlm.nih.gov/29107292
https://pubmed.ncbi.nlm.nih.gov/29107292
Autor:
Kliewer KL; a Department of Human Sciences ; College of Education and Human Ecology ; The Ohio State University ; Columbus , OH USA., Ke JY, Tian M, Cole RM, Andridge RR, Belury MA
Publikováno v:
Cancer biology & therapy [Cancer Biol Ther] 2015; Vol. 16 (6), pp. 886-97. Date of Electronic Publication: 2014 Dec 02.