Zobrazeno 1 - 10
of 104
pro vyhledávání: '"i.p., intraperitoneal"'
Autor:
Matías Bayley, María Inés Ragone, Soledad Inés Matera, Germán A. Colareda, María L. Flores, Osvaldo León Córdoba, Alicia E. Consolini
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 11, Iss 6, Pp 471-480 (2021)
Journal of Traditional and Complementary Medicine
Journal of Traditional and Complementary Medicine
Background and aim Phytoestrogens are traditionally used for cardiovascular risks but direct effects on the ischemic heart remain unclear. Plants with phytoestrogens are used for reducing menopausic symptoms and they could also be cardioprotectives.
Autor:
Jinze Li, Maria M. Disotuar, Nai-Pin Lin, Jake A. Smith, Danny Hung-Chieh Chou, Steve L. Alam
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2719-2725 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Insulin derivatives such as insulin detemir and insulin degludec are U.S. Food and Drug Administration (FDA)-approved long-acting insulin currently used by millions of people with diabetes. These derivatives are modified in C-terminal B29 lysine to r
Autor:
Siying Zhu, Matthew S. Tremblay, Sean B. Joseph, Seung Hyuk Choi, Mitch Hull, Weijun Shen, Valeria Marrocco, Sijia Li, Marta Diez Cunado, Ana M. Gamo, Tuan Tran, Jason Roland, Arnab K. Chatterjee, Qiangwei Fu, Van Nguyen-Tran, Nikki Rogers
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3983-3993 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3983-3993 (2021)
Unfolded protein response (UPR) is a stress response that is specific to the endoplasmic reticulum (ER). UPR is activated upon accumulation of unfolded (or misfolded) proteins in the ER's lumen to restore protein folding capacity by increasing the sy
Autor:
Vijay R. Chidrawar, Bader Alsuwayt
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
In the present study, we have investigated and/or compared the role of glibenclamide, G as cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor, and lubiprostone, L as chloride channel-2 (ClC-2) activator in the 2,4-dinitrobenzene sul
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 322-339 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Fibrosis is a pathological reparative process that can occur in most organs and is responsible for nearly half of deaths in the developed world. Despite considerable research, few therapies have proven effective and been approved clinically for treat
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 8, Pp 2174-2184 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Testicular torsion and detorsion (TTD) is a serious urological condition affecting young males that is underlined by an ischemia reperfusion injury (tIRI) to the testis as the pathophysiological mechanism. During tIRI, uncontrolled production of oxyg
Autor:
Ping Zhang, Dingyuan Ma, Li-Ying Peng, Ning-Yuan Sun, Jun Chen, Xiao-Wei Zhang, Weiwei Tang, Lin An
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1397-1413 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1397-1413 (2020)
Pyroptosis is a form of programmed cell death, and recently described as a new molecular mechanism of chemotherapy drugs in the treatment of tumors. Miltirone, a derivative of phenanthrene-quinone isolated from the root of Salvia miltiorrhiza Bunge,
Publikováno v:
IBRO Reports, Vol 8, Iss, Pp 36-47 (2020)
IBRO Reports
IBRO Reports
Highlights • Recovery of neural cells is higher with 30 % Percoll gradient than 30–70 %. • Papain enhances combined extraction of microglia, astrocytes and lymphocytes. • Dispase II potentiates papain action only in adult brain. • Mechanica
Publikováno v:
Metabolism Open, Vol 12, Iss, Pp 100146-(2021)
Metabolism Open
Metabolism Open
Growing evidence suggests that oxytocin (OT) plays an important factor for the control of food intake, body weight, and energy metabolism in human and non-human animals. It has reported previously, the downregulation in oxytocin receptors (OTRs) expr
Autor:
Mara Rigamonti, Roberto Chiesa, Ihssane Bouybayoune, Elena Restelli, Ilaria Bertani, Luca Porcu, Stefano Zordan, Antonio Masone, Giada Lavigna, Jacopo Lucchetti, Luca Imeri, Marco Gobbi
Publikováno v:
Neurobiology of Disease, Vol 158, Iss, Pp 105455-(2021)
Neurobiology of Disease
Neurobiology of Disease
Fatal familial insomnia (FFI) is a dominantly inherited prion disease linked to the D178N mutation in the gene encoding the prion protein (PrP). Symptoms, including insomnia, memory loss and motor abnormalities, appear around 50 years of age, leading