Zobrazeno 1 - 10
of 1 084
pro vyhledávání: '"hypothesis of schizophrenia"'
Autor:
Kinga Brzuszkiewicz, Gracjan Rudziński, Borys Łozowski, Przemysław Raczkiewicz, Natalia Kusak, Ewelina Soroka
Publikováno v:
Journal of Education, Health and Sport, Vol 23, Iss 1 (2023)
Introduction: Schizophrenia is a psychotic disease characterized by multifaceted psychopathology. To date, research has shown that it is an inherited disease and significant progress has been made in identifying genetic risk factors. Methods: This
Externí odkaz:
https://doaj.org/article/20195586d3fc482dae3761ddfef20536
Autor:
Justyna Dąbrowska, Magdalena Wójcik, Julita Szarpak, Damian Bator, Joanna Milanowska, Hubert Nieścior
Publikováno v:
Journal of Education, Health and Sport, Vol 10, Iss 8, Pp 332-339 (2020)
Introduction: Schizophrenia is one of the most serious and frightening of all mental illnesses. It affects almost 1% of the population worldwide. The main concept and treatment of schizophrenia are based on the dopaminergic hypothesis. However, accum
Externí odkaz:
https://doaj.org/article/820f4e80c56f4ff5bf119e006a78262e
Autor:
Jonathan Pimm, John Cookson
Publikováno v:
BJPsych Advances. 29:141-144
SUMMARYThis article discusses dopamine partial agonism, which is the main mechanism of action of the psychiatric drugs aripiprazole, brexpiprazole and cariprazine. It outlines the principles of receptor theory and the structure of dopamine receptors;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f467bbc56f9b9855ebb7c621f7d81386
https://doi.org/10.1192/bja.2021.39
https://doi.org/10.1192/bja.2021.39
Autor:
Julita Szarpak, Joanna Milanowska, Damian Bator, Justyna Dąbrowska, Hubert Nieścior, Magdalena Wójcik
Publikováno v:
Journal of Education, Health and Sport, Vol 10, Iss 8, Pp 332-339 (2020)
Dąbrowska Justyna, Wójcik Magdalena, Szarpak Julita, Bator Damian, Milanowska Joanna, Nieścior Hubert. Theories of the pathogenesis of schizophrenia. Journal of Education, Health and Sport. 2020;10(8):332‑339. eISSN 2391-8306. DOI http://dx.doi.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35e35746eb5bbe0f29917af33d5deea
https://zenodo.org/record/3996262
https://zenodo.org/record/3996262
Publikováno v:
Frontiers in Cellular Neuroscience, 15
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
According to the tripartite synapse model, astrocytes have a modulatory effect on neuronal signal transmission. More recently, astrocyte malfunction has been associated with psychiatric diseases such as schizophrenia. Several hypotheses have been pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da62e8e7b0c18e44cda7f52e7673461
https://doi.org/10.3389/fncel.2021.718459
https://doi.org/10.3389/fncel.2021.718459
Autor:
Drozdstoy Stoyanov, Katrin Aryutova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9309, p 9309 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The neurodegenerative and neurodevelopmental hypotheses represent the basic etiological framework for the origin of schizophrenia. Additionally, the dopamine hypothesis, adopted more than two decades ago, has repeatedly asserted the position of dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29532cdf882a8f84a1baaf66b10fdb5
https://www.mdpi.com/1422-0067/22/17/9309
https://www.mdpi.com/1422-0067/22/17/9309
Autor:
Anna Partyka, Andrzej J. Bojarski, Grażyna Chłoń-Rzepa, Grzegorz Satała, Anna Wesołowska, Maciej Pawłowski, Agnieszka Jankowska
Publikováno v:
Current Medicinal Chemistry. 26:4885-4913
Schizophrenia is a chronic psychiatric disorder that affects about 1 in 100 people around the world and results in persistent emotional and cognitive impairments. Untreated schizophrenia leads to deterioration in quality of life and premature death.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffd424e01e2834dfce5e6c0e7f74b63
https://doi.org/10.2174/0929867326666190710172002
https://doi.org/10.2174/0929867326666190710172002
Publikováno v:
Schizophrenia Research. 210:13-20
The glutamate hypothesis of schizophrenia posits aberrant glutamatergic activity in patients with schizophrenia. Levels of glutamate and glutamine can be detected and quantified in vivo by proton magnetic resonance spectroscopy. A related technique,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837b73d207398f76b67c06e430167f4b
https://doi.org/10.1016/j.schres.2019.06.011
https://doi.org/10.1016/j.schres.2019.06.011
Autor:
Or Duek
Publikováno v:
eNeuro
Animal models suggest that interactions between the hippocampus and ventral tegmental area (VTA) underlie the onset and etiology of psychosis. While a large body of research has separately characterized alterations in hippocampal and VTA function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42624c0960b58cc9862fc3c839647e45
https://pubmed.ncbi.nlm.nih.gov/33658310
https://pubmed.ncbi.nlm.nih.gov/33658310
Autor:
Mary V. Seeman
Publikováno v:
World Journal of Psychiatry
The dopamine hypothesis of how antipsychotic drugs exert their beneficial effect in psychotic illness has an interesting history that dates back to 1950. This hypothesis is not to be confused with the dopamine hypothesis of schizophrenia; the aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81e06a06a810875fd78681c29d1c5bd
https://pubmed.ncbi.nlm.nih.gov/34327128
https://pubmed.ncbi.nlm.nih.gov/34327128