Zobrazeno 1 - 10
of 15 012
pro vyhledávání: '"hypermethylation"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Diabetes mellitus (DM)-induced testicular damage is associated with sexual dysfunction and male infertility in DM patients. However, the pathogenesis of DM-induced testicular damage remains largely undefined. Methods A streptozoto
Externí odkaz:
https://doaj.org/article/2324ea5fd3b4414e822a0f357e1b1a80
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 10, Pp 1791-1799 (2024)
AIM: To explore the DNA methylation of COL4A1 in ultraviolet-B (UVB)-induced age-related cataract (ARC) models in vitro and in vivo. METHODS: Human lens epithelium B3 (HLEB3) cells and Sprague Dawley rats were exposure to UVB respectively. The MTT as
Externí odkaz:
https://doaj.org/article/b9dd3ebfbaca4ce0b549edc95003b302
Autor:
Fozia Mohammad, Arshad A. Pandith, Shayaq Ul Abeer Rasool, Faisal R. Guru, Iqbal Qasim, Sajad Geelani, Syed Nisar, Shahid M. Baba, Farooq A. Ganie, Safiya Kouser, Javid Rasool
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Background Fragile histidine triad (FHIT) has been documented to play a vital role in various cancers including acute lymphoblastic leukemia (ALL). Keeping in view the plausible role of FHIT gene, we aimed to examine DNA promoter hypermethyl
Externí odkaz:
https://doaj.org/article/3571ebc54cc54c178211e60dbafa3ce8
Autor:
Danyang Li, Yigang Yuan, Chen Meng, Zihan Lin, Min Zhao, Liuzhi Shi, Min Li, Daijiao Ye, Yue Cai, Xiaofei He, Haige Ye, Shujuan Zhou, Haixia Zhou, Shenmeng Gao
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background miR-182 promoter hypermethylation frequently occurs in various tumors, including acute myeloid leukemia, and leads to low expression of miR-182. However, whether adult acute lymphocyte leukemia (ALL) cells have high miR-182 promot
Externí odkaz:
https://doaj.org/article/c44c05750ee741bc967316cdfdac82e9
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Lymphatic system distributes in almost all vertebrate tissues and organs, and plays important roles in the regulation of body fluid balance, lipid absorption and immune monitoring. Although CuNPs or AgNPs accumulation has been reported to be
Externí odkaz:
https://doaj.org/article/0e0e0d8610a3401b81285546630ef009
Autor:
Xiuqin Bao, Yuanyi Gao, Zhongju Wang, Yuhua Ye, Diyu Chen, Yangjin Zuo, Cunyou Zhao, Xiangmin Xu
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-5 (2024)
Abstract The mechanism that drives the switch from fetal to adult hemoglobin (Hb) provides a therapeutic target for β-thalassemia. We have previously identified that hypermethylation of transcription factor ERF promoter reactivated γ-globin express
Externí odkaz:
https://doaj.org/article/0aa26d52d8a142a59376cc32bd6068e3
Akademický článek
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Autor:
Harem O. Smail
Publikováno v:
Science Journal of University of Zakho, Vol 12, Iss 2 (2024)
Background: Chronic hyperglycemia and insulin resistance are two hallmarks of type 2 diabetes mellitus (T2DM), a complicated metabolic disease. The purpose of the current investigation was to identify Non-CPG methylation in the ABCC8 and CAPN10 promo
Externí odkaz:
https://doaj.org/article/5ddd7c5fdc9c49e5bca4002c06852111
Publikováno v:
Practical Laboratory Medicine, Vol 40, Iss , Pp e00406- (2024)
Aim: The current study aimed to assess the frequency of CDH1 promoter gene hypermethylation in gastric cancer and chronic gastritis and its correlation with clinicopathological aspects. Methods: Methylation-specific PCR was used to detect CDH1 promot
Externí odkaz:
https://doaj.org/article/89cc6c855e684a3d8ec81c36203f8769
Autor:
Fuqiang Zhao, Ping Bai, Jianfeng Xu, Zitong Li, Shan Muhammad, Diange Li, Zeyue Zhang, Yibo Gao, Qian Liu
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Background Although colonoscopy is the standard screening test for colorectal cancer (CRC), its use is limited by a poor compliance rate, the need for extensive bowel preparation, and the risk of complications. As an alternative, an FDA-appr
Externí odkaz:
https://doaj.org/article/9aa718a70e8b46c59567099612d018c5