Zobrazeno 1 - 10
of 292
pro vyhledávání: '"hydroxynonenal"'
Autor:
Tetsumori Yamashima, Daria Mochly-Rosen, Soichi Wakatsuki, Eishiro Mizukoshi, Takuya Seike, Isabel Maria Larus, Che-Hong Chen, Miho Takemura, Hisashi Saito, Akihiro Ohashi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Autophagy mediates the degradation of intracellular macromolecules and organelles within lysosomes. There are three types of autophagy: macroautophagy, microautophagy, and chaperone-mediated autophagy. Heat shock protein 70.1 (Hsp70.1) exhibits dual
Externí odkaz:
https://doaj.org/article/eee398e828314d8f9bda7fabb7eb97e6
Autor:
Tetsumori Yamashima, Takuya Seike, Shinji Oikawa, Hatasu Kobayashi, Hidenori Kido, Masahiro Yanagi, Daisuke Yamamiya, Shihui Li, Piyakarn Boontem, Eishiro Mizukoshi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Alzheimer’s disease, type 2 diabetes, and non-alcoholic steatohepatitis (NASH) constitute increasingly prevalent disorders. Individuals with type 2 diabetes are well-known to be susceptible to Alzheimer’s disease. Although the pathogenesis of eac
Externí odkaz:
https://doaj.org/article/cc785862cf064f9fb7b307fb88fadf26
Autor:
Lucia La Sala, Elena Tagliabue, Simona Mrakic-Sposta, Anna Chiara Uccellatore, Pamela Senesi, Ileana Terruzzi, Emilio Trabucchi, Luigi Rossi-Bernardi, Livio Luzi
Publikováno v:
Cardiovascular Diabetology, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Background The prevalence of prediabetes is increasing in the global population and its metabolic derangements may expose to a higher risk to develop type 2 diabetes (T2D) and its cardiovascular burden. Lifestyle modifications might have con
Externí odkaz:
https://doaj.org/article/021ce3c1c0cb4347a982ded45de293e7
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 329 (2023)
High concentrations of electrophilic lipid alkenals formed during oxidative stress are implicated in cytotoxicity and disease. However, low concentrations of alkenals are required to induce antioxidative stress responses. An established clearance pat
Externí odkaz:
https://doaj.org/article/e270b1016b824c80bcc9e3e37b0b99f2
Autor:
Tetsumori Yamashima
Publikováno v:
Nutrients, Vol 15, Iss 3, p 609 (2023)
Lysosomes are membrane-bound vesicular structures that mediate degradation and recycling of damaged macromolecules and organelles within the cell. For ensuring the place of degradation within the acidic organelle, the integrity of the lysosomal-limit
Externí odkaz:
https://doaj.org/article/c5d9f4955d4d45bba431a2bdd18f2602
Autor:
Antolín Cantó, Javier Martínez-González, Inmaculada Almansa, Rosa López-Pedrajas, Vicente Hernández-Rabaza, Teresa Olivar, María Miranda
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1950 (2022)
(1) Background: Retinitis pigmentosa (RP) is characterized by progressive photoreceptor death. A Prph2Rd2 or an rds mouse is an RP model that closely reflects human RP. The objective of this study was to investigate the relationship of rod and cone d
Externí odkaz:
https://doaj.org/article/67b864c35ca1427ca2acf23383154677
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2004 Dec . 101(52), 17964-17969.
Externí odkaz:
https://www.jstor.org/stable/3374177
Autor:
Balu K. Chacko, Stephanie B. Wall, Philip A. Kramer, Saranya Ravi, Tanecia Mitchell, Michelle S. Johnson, Landon Wilson, Stephen Barnes, Aimee Landar, Victor M. Darley-Usmar
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 57-66 (2016)
Metabolic control of cellular function is significant in the context of inflammation-induced metabolic dysregulation in immune cells. Generation of reactive oxygen species (ROS) such as hydrogen peroxide and superoxide are one of the critical events
Externí odkaz:
https://doaj.org/article/fb40ea8e5b29407f8aa0bf4456c53851
Autor:
Khrystyna Semen, Olha Yelisyeyeva, Iwona Jarocka-Karpowicz, Danylo Kaminskyy, Lyubomyr Solovey, Elzbieta Skrzydlewska, Ostap Yavorskyi
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 48-57 (2016)
Pulmonary arterial hypertension (PAH) is a rare multifactorial disease with an unfavorable prognosis. Sildenafil therapy can improve functional capacity and pulmonary hemodynamics in PAH patients. Nowadays, it is increasingly recognized that the effe
Externí odkaz:
https://doaj.org/article/bb5a048df90d46118c5c4897d7b640c7
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