Zobrazeno 1 - 10
of 465
pro vyhledávání: '"hybrid peptide"'
Autor:
Junyong Wang, Yuan Tang, Xuelian Zhao, Zetao Ding, Marhaba Ahmat, Dayong Si, Rijun Zhang, Xubiao Wei
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Thymopentin (TP5) plays an important role in host immunomodulation, yet its bioavailability is significantly limited by its short half-life. YW12D is a peptide with strong stability but relatively weak immunoactivity. Tuning the physicochemical prope
Externí odkaz:
https://doaj.org/article/7e092654f81f4df091a1f030407d1290
Publikováno v:
iRADIOLOGY, Vol 2, Iss 2, Pp 128-155 (2024)
Abstract Optimal therapeutic and diagnostic efficacy is essential for healthcare's global mission of advancing oncologic drug development. Accurate diagnosis and detection are crucial prerequisites for effective risk stratification and personalized p
Externí odkaz:
https://doaj.org/article/581ec3af255d4077ac1263947fae3b69
Autor:
Kang Qian, Peng Yang, Yixian Li, Ran Meng, Yunlong Cheng, Lingling Zhou, Jing Wu, Shuting Xu, Xiaoyan Bao, Qian Guo, Pengzhen Wang, Minjun Xu, Dongyu Sheng, Qizhi Zhang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100938- (2024)
Alzheimer's disease is a neurodegenerative disease induced by multiple interconnected mechanisms. Peptide drug candidates with multi-modal efficacy generated from fusion strategy are suitable for addressing multi-facet pathology. However, clinical tr
Externí odkaz:
https://doaj.org/article/403f74994e394d2e9ed2d13b852fc61f
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 18, Pp 173-180 (2023)
Objective: To reveal the bacteriostatic activity of hybrid antimicrobial peptide NK-LPd, and discuss its further exploitation potential. Methods: Two glycines were utilized as the linker to connect the active fragments of NK-lysin and Piscidin, and t
Externí odkaz:
https://doaj.org/article/51551941ed5546bc9ff411e5c780a169
Akademický článek
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Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Physical hydrogels prepared from natural biopolymers are the most popular components for bioinks. However, to improve the mechanical properties of the network, in particular its durability for long-lasting tissue engineering applications or its stiff
Externí odkaz:
https://doaj.org/article/f6e1fca8bd8d44b39ea8ed5689ad9bbe
Akademický článek
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Akademický článek
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Autor:
Pawel Serafin, Paweł Kowalczyk, Adriano Mollica, Azzurra Stefanucci, Anna K. Laskowska, Magdalena Zawadzka, Karol Kramkowski, Patrycja Kleczkowska
Publikováno v:
Molecules, Vol 28, Iss 13, p 4955 (2023)
Finding the ideal antimicrobial drug with improved efficacy and a safety profile that eliminates antibiotic resistance caused by pathogens remains a difficult task. Indeed, there is an urgent need for innovation in the design and development of a mic
Externí odkaz:
https://doaj.org/article/b88636f398ef46cc9ed9dedfefa61821
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract Background There is a need to develop new and more potent radiofluorinated peptide and their hybrid conjugates for multiple-receptors targeting properties that overexpress on many cancers. Methods We have synthesized MUC1-[18F] SFB and MUC1-
Externí odkaz:
https://doaj.org/article/0e770066d9024060a0a8dfe55ff4da16