Zobrazeno 1 - 10
of 38 877
pro vyhledávání: '"human-plasma"'
Autor:
Anna Błażewicz, Julia Wojnicka, Andreas M. Grabrucker, Piotr Sosnowski, Alicja Trzpil, Anna Kozub-Pędrak, Klaudia Szałaj, Agnieszka Szmagara, Ewelina Grywalska, Katarzyna Skórzyńska-Dziduszko
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract The present preliminary study aimed to provide a targeted lipidomic analysis of Hashimoto (HT) and non-HT patients with well-controlled hypothyroidism as well as in healthy adults, and is the first to demonstrate the association of several c
Externí odkaz:
https://doaj.org/article/783eea637ff6442ca5f058216ae1d363
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4877-4887 (2024)
Na Zhang,1,* Yiran Xu,1,2,* Beibei Liang,1 Jinru Zeng,1 Rui Wang,1 Yun Cai1 1Center of Medicine Clinical Research, Department of Pharmacy, Medical Supplies Center, PLA General Hospital, Beijing, People’s Republic of China; 2Department of Ph
Externí odkaz:
https://doaj.org/article/831f6297fa034c428fbee0a07657f4bf
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract A sustainable HPTLC-densitometric method was developed for quantitative determination of Quetiapine (QUET), Levodopa (LD) and Carbidopa (CD) in presence of Dopamine (DOP) as an internal standard. This applicable technique was achieved by spi
Externí odkaz:
https://doaj.org/article/cff29680a03e467690f7431bb491ec1c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract A novel, environmentally friendly, and sensitive HPTLC method has been developed and validated for simultaneous quantification of duloxetine (DLX) and tadalafil (TDL) in their pure state, laboratory-prepared mixtures, and spiked human plasma
Externí odkaz:
https://doaj.org/article/46e20f1aa8d3485f94f5e01509af4097
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Background This study developed and validated a simple, robust, and cost-effective RP-HPLC bioanalytical method for the determination of nebivolol hydrochloride (NBH) and amlodipine besylate (AMB) in human plasma. Briefly, NBH and AMB were e
Externí odkaz:
https://doaj.org/article/2f6f212d5fd94154a0818bd7b4bf9b23
Autor:
Yuri D. Ivanov, Ekaterina D. Nevedrova, Angelina V. Vinogradova, Kristina V. Goldaeva, Tatyana O. Pleshakova, Rafael A. Galiullin, Alexander N. Ableev, Ivan D. Shumov, Andrey F. Kozlov, Vladimir P. Popov, Nikolay E. Kushlinskii, Ivan S. Stilidi, Zaman Z. Mamedli, Dmitry V. Enikeev, Natalia V. Potoldykova, Vladimir A. Konev, Oleg B. Kovalev, Vadim S. Ziborov, Leonid I. Grishin, Alexander Y. Dolgoborodov, Oleg F. Petrov, Alexander I. Archakov
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 120-131 (2024)
Rationale: Colorectal cancer (CRC) is one of the most prevalent oncological diseases with high mortality. Invasive optical (endoscopic) colono- scopy has been recognized as a golden standard for the CRC diagnostics. A promising area is the developmen
Externí odkaz:
https://doaj.org/article/22f430a0240641ffbc212c3f691b49e1
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Guaifenesin (GUA) is determined in dosage forms and plasma using two methods. The spectrofluorimetric technique relies on the measurement of native fluorescence intensity at 302 nm upon excitation wavelength “223 nm”. The method was vali
Externí odkaz:
https://doaj.org/article/148eaedd6f7b4386a1e39d8d5b205ade
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract A novel antipsychotic medication named brexpiprazole (BRX) is currently employed for the treatment of schizophrenia and other psychotic disorders. Because BRX’s molecular structure includes a benzothiophene ring, it natively fluoresces. To
Externí odkaz:
https://doaj.org/article/e995ffe838a445369a005d599928cf08
Autor:
P.-C. Violet, N. Munyan, H.F. Luecke, Y. Wang, J. Lloyd, K. Patra, K. Blakeslee, I.C. Ebenuwa, M. Levine
Publikováno v:
Redox Biology, Vol 78, Iss , Pp 103425- (2024)
Ascorbic acid (AA, vitamin C) and dehydroascorbic acid (DHA) constitute a biological couple. No technique can accurately, independently, and simultaneously quantify both members of the couple in animal and human samples, thereby constraining advances
Externí odkaz:
https://doaj.org/article/e2a760a1cac848698d5833faa5e9b388
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 11, Pp 100671- (2024)
Liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS)-based methods have become the gold standard methodology for the comprehensive profiling of the human plasma lipidome. However, both the complexity of lipid chemistry and LC-
Externí odkaz:
https://doaj.org/article/741414b5ae2d49bcb4099fc853ca7f2a