Zobrazeno 1 - 10
of 13 287
pro vyhledávání: '"human skeletal-muscle"'
Autor:
Daniel Jacko, Lukas Masur, Kirill Schaaf, Jonas Zacher, Käthe Bersiner, Markus deMarées, Wilhelm Bloch, Sebastian Gehlert
Publikováno v:
Physiological Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Lipofuscin (LF) is an intracellular aggregate associated with proteostatic impairments, especially prevalent in nondividing skeletal muscle fibers. Reactive oxygen species (ROS) drive LF‐formation. Resistance training (RT) improves muscle
Externí odkaz:
https://doaj.org/article/9de2453f360d4e1a83e0ee1c69311207
Autor:
Shuming Sun, Han Liu, Yan Hu, Yanpeng Wang, Mingri Zhao, Yijun Yuan, Yafei Han, Yingying Jing, Jin Cui, Xiaoxiang Ren, Xiao Chen, Jiacan Su
Publikováno v:
Bioactive Materials, Vol 20, Iss , Pp 166-178 (2023)
Skeletal muscle disorders have posed great threats to health. Selective delivery of drugs and oligonucleotides to skeletal muscle is challenging. Aptamers can improve targeting efficacy. In this study, for the first time, the human skeletal muscle-sp
Externí odkaz:
https://doaj.org/article/3d5f8ae5d06b4ba18f34184bdfd5d8b6
Acyl‐CoA synthetase expression in human skeletal muscle is reduced in obesity and insulin resistance
Autor:
Margarete Poppelreuther, Anne‐Marie Lundsgaard, Pernille Mensberg, Kim Sjøberg, Tina Vilsbøll, Bente Kiens, Joachim Füllekrug
Publikováno v:
Physiological Reports, Vol 11, Iss 18, Pp n/a-n/a (2023)
Abstract Upon intramuscular entry, fatty acids are converted to amphiphatic fatty acyl‐CoAs by action of the acyl‐CoA synthetase (ACS) enzymes. While it has been reported that insulin resistant skeletal muscle shows an accumulation of fatty acyl
Externí odkaz:
https://doaj.org/article/6a0a4a12c6464808912a29c001f6bcab
Autor:
Rodrigo Mancilla, Diego Pava‐Mejia, Nynke vanPolanen, Vera deWit, Maaike Bergman, Lotte Grevendonk, Johanna Jorgensen, Esther Kornips, Joris Hoeks, Matthijs K. C. Hesselink, Vera B. Schrauwen‐Hinderling
Publikováno v:
Physiological Reports, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract Mitochondria are organelles that fuel cellular energy requirements by ATP formation via aerobic metabolism. Given the wide variety of methods to assess skeletal muscle mitochondrial capacity, we tested how well different invasive and noninva
Externí odkaz:
https://doaj.org/article/e51d1203343b480098a2feb69c51dec1
Akademický článek
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Autor:
Marta Murgia, Leonardo Nogara, Martina Baraldo, Carlo Reggiani, Matthias Mann, Stefano Schiaffino
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Background Human skeletal muscle is composed of three major fiber types, referred to as type 1, 2A, and 2X fibers. This heterogeneous cellular composition complicates the interpretation of studies based on whole skeletal muscle lysate. A sin
Externí odkaz:
https://doaj.org/article/9a2d90d6736b4e079c06502c1b989d35
Relationship Between METTL21C Gene Expression and Exercise in Human Skeletal Muscle: A Meta-Analysis
Publikováno v:
운동과학, Vol 30, Iss 1, Pp 102-109 (2021)
Purpose Recently, METTL21C has been identified as a potential pleiotropic gene for osteoporosis and sarcopenia. The purpose of this study was to collect gene expression datasets of human skeletal muscle transcriptome and to determine their relationsh
Externí odkaz:
https://doaj.org/article/0d101f38856a4d8eae29fb645273740e
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background Maintaining stem cells in physiologically relevant states is necessary to understand cell and context-specific signalling paradigms and to understand complex interfaces between cells in situ. Understanding human stem cell function
Externí odkaz:
https://doaj.org/article/0e66820fa3bf4bc6ac686df0cc30cff3
Autor:
Simone Mosole, Katia Rossini, Helmut Kern, Stefan Löfler, Hannah Fruhmann, Michael Vogelauer, Samantha Burggraf, Martina Grim-Stieger, Ján Cvečka, Dušan Hamar, Milan Sedliak, Nejc Šarabon, Amber Pond, Donatella Biral, Ugo Carraro, Sandra Zampieri
Publikováno v:
European Journal of Translational Myology (2022)
In 2013 we presented results showing that at the histological level lifelong increased physical activity promotes reinnervation of muscle fibers in aging muscles. Indeed, in muscle biopsies from 70-year old men with a lifelong history of high-level p
Externí odkaz:
https://doaj.org/article/ea5cb6cdd4e846eb9ebb9f02f4dc02d5