Zobrazeno 1 - 10
of 156
pro vyhledávání: '"human peritoneal mesothelial cells"'
Autor:
Hong-yong Su, Jia-jie Yang, Rong Zou, Ning An, Xiao-cui Chen, Chen Yang, Hai-juan Yang, Cui-wei Yao, Hua-feng Liu
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Peritoneal dialysis (PD) is a widely accepted renal replacement therapy for patients with end-stage renal disease (ESRD). Morphological and functional changes occur in the peritoneal membranes (PMs) of patients undergoing long-term PD. Peritoneal fib
Externí odkaz:
https://doaj.org/article/4a2e7d5b88034bc0b45635143bc6d1a1
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-15 (2020)
Abstract Background Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis (PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an important role in maintaining structure and function in the
Externí odkaz:
https://doaj.org/article/4edd97dd706d4c809ce7d875ae78ba6f
Autor:
Yao Zhou, Weiming He, Wei Sun, Zhanwei Zhou, Minjie Sun, Ping Xia, Wei Li, Min Zheng, Lu Zhang, Jie Ni, Kun Gao
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 6, Pp 2434-2444 (2018)
Background/Aims: Long-term use of high-glucose peritoneal dialysis solution (PDS) induces peritoneal mesothelial cell (PMC) injury, peritoneal dysfunction, and peritoneal dialysis (PD) failure in patients with end-stage renal disease. How to preserve
Externí odkaz:
https://doaj.org/article/1a2ac64f7d434e9fa521b1a43df856d5
Autor:
Yi Wang, Shenglei Zhang, Binbin Cui, Jun Wang, Susie Hu, Na Liu, Chao Yu, Shougang Zhuang, Feng Liu, Lu Fang, Huan Qin
Publikováno v:
Journal of Cellular and Molecular Medicine
Nintedanib, an Food and Drug Administration (FDA) approved multiple tyrosine kinase inhibitor, exhibits an anti‐fibrotic effect in lung and kidneys. Its effect on peritoneal fibrosis remains unexplored. In this study, we found that nintedanib admin
Autor:
Ming-Wen Che, Guo-Shun Xu, Du-Jing-Zi Gong, Jian-Le Zhao, Jing Li, Ya-Rong Chen, Xi Jiang, Xing-Jie Ma, Li-Jie He
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 45, Iss 9, Pp 904-912 (2020)
Objective To explore the relationship between Kruppel-like factor 4 (KLF-4) and E-cadherin in human peritoneal mesothelial cells (HPMCs), and the expression and function of KLF-4 in the animal model of peritoneal fibrosis induced by high glucose peri
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 43, Iss 3, Pp 189-194 (2018)
Objective To explore the role of long noncoding RNA-MGC (lnc-MGC) on the trans-differentiation of human peritoneal mesothelial cells (HPMCs) induced by high glucose. Methods The immortalized HPMCs were used to establish control group and high glucose
Autor:
Ming-wen CHE, Feng-rong LI, Li-fang GONG, Xiu-feng FANG, Hai-ping DENG, Xi JIANG, Ya-wei TANG, Han-min WANG
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 42, Iss 9, Pp 781-787 (2017)
Objective To explore the effects of p53 up-regulated modulator of apoptosis (PUMA)-α protein on the apoptosis and fibrosis of human peritoneal mesothelial cells (HPMCs) induced by high glucose. Methods HPMCs were induced by 50mmol/L D type glucose o
Autor:
Zibin Wang, Aiqin Jiang, Fang Wang, Wu Jingjing, Haibin Ren, Xuguan Chen, Li Zhang, Meijuan Zou, Huijuan Mao, Changying Xing, Cui Hongqing, Mingxing Liang, Yong Ji
Publikováno v:
Journal of Cellular and Molecular Medicine
Long‐term peritoneal dialysis is accompanied by functional and histopathological alterations in the peritoneal membrane. In the long process of peritoneal dialysis, high‐glucose peritoneal dialysis solution (HGPDS) will aggravate the peritoneal f
Publikováno v:
Molecular Medicine Reports
Zinc (Zn) deficiency is important for inducing nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing-3 (NLRP3) inflammasome activation in macrophages. However, its function in the NLRP3 inflammasome activation o
Autor:
Itasu Ninomiya, Hiroto Saito, Tetsuo Ohta, Sachio Fushida, Tomoya Tsukada, Hidehiro Tajima, Tomoharu Miyashita, Takahisa Yamaguchi, Jun Kinoshita, Shinichi Harada, Katsunobu Oyama
Publikováno v:
Gastric Cancer
Background Scirrhous gastric cancer is an intractable disease with a high incidence of peritoneal dissemination and obstructive symptoms (e.g., ileus, jaundice, and hydronephrosis) arising from accompanying marked fibrosis. Microenvironmental interac