Deep functional measurements of Fragile X syndrome human neurons reveal multiparametric electrophysiological disease phenotype.

Autor: Fink, James J.^1,2 (AUTHOR), Delaney-Busch, Nathaniel² (AUTHOR), Dawes, Ryan³ (AUTHOR), Nanou, Evanthia³ (AUTHOR), Folts, Christopher³ (AUTHOR), Harikrishnan, Karthiayani^1,2 (AUTHOR), Hempel, Chris² (AUTHOR), Upadhyay, Hansini² (AUTHOR), Nguyen, Trinh² (AUTHOR), Shroff, Himali² (AUTHOR), Stoppel, David⁴ (AUTHOR), Ryan, Steven J.^1,2 (AUTHOR), Jacques, Jane^1,2 (AUTHOR), Grooms, Jennifer^1,2 (AUTHOR), Berry-Kravis, Elizabeth⁵ (AUTHOR), Bear, Mark F.⁴ (AUTHOR), Williams, Luis A.^1,2 (AUTHOR), Gerber, David^1,2 (AUTHOR), Bunnage, Mark³ (AUTHOR), Furey, Brinley³ (AUTHOR)

Publikováno v: Communications Biology. 11/6/2024, Vol. 7 Issue 1, p1-15. 15p.

Carvedilol suppresses ryanodine receptor-dependent Ca²⁺ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease.

Autor: Hori, Atsushi¹ (AUTHOR), Inaba, Haruka² (AUTHOR), Hato, Takashi³ (AUTHOR), Tanaka, Kimie² (AUTHOR), Sato, Shoichi⁴ (AUTHOR), Okamoto, Mizuho^2,5 (AUTHOR), Horiuchi, Yuna¹ (AUTHOR), Paran, Faith Jessica² (AUTHOR), Tabe, Yoko² (AUTHOR), Mori, Shusuke⁶ (AUTHOR), Rosales, Corina^7,8 (AUTHOR), Akamatsu, Wado⁵ (AUTHOR), Murayama, Takashi⁹ (AUTHOR), Kurebayashi, Nagomi⁹ (AUTHOR), Sakurai, Takashi⁹ (AUTHOR), Ai, Tomohiko^2,6,10 (AUTHOR) t-ai@juntendo.ac.jp, Miida, Takashi^1,2 (AUTHOR)

Publikováno v: PLoS ONE. 8/22/2024, Vol. 19 Issue 8, p1-17. 17p.

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Circuit integration by transplanted human neurons

Autor: Yuan, Qiang, Zhang, Su-Chun

Publikováno v: In Current Opinion in Genetics & Development December 2024 89