Zobrazeno 1 - 10
of 3 698
pro vyhledávání: '"human macrophages"'
Autor:
Gül Kilinç, Ralf Boland, Matthias T. Heemskerk, Herman P. Spaink, Mariëlle C. Haks, Michiel van der Vaart, Tom H. M. Ottenhoff, Annemarie H. Meijer, Anno Saris
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Mycobacterium tuberculosis (Mtb) as well as nontuberculous mycobacteria are intracellular pathogens whose treatment is extensive and increasingly impaired due to the rise of mycobacterial drug resistance. The loss of antibiotic efficacy has
Externí odkaz:
https://doaj.org/article/2939a79ee24140a7a75c5c4c4f1addde
Autor:
Matthew Herring, Alexander Persson, Ryan Potter, Roger Karlsson, Eva Särndahl, Mikael Ejdebäck
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32023- (2024)
The NLRP3 inflammasome is an intracellular multiprotein complex described to be involved in both an effective host response to infectious agents and various diseases. Investigation into the NLRP3 inflammasome has been extensive in the past two decade
Externí odkaz:
https://doaj.org/article/6978bebb59b74e4d8879b62202a3c026
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background The purinergic receptor P2X7 plays a crucial role in infection, inflammation, and cell death. It is thought that P2X7 receptor stimulation triggers processing and release of the pro-inflammatory cytokine interleukin (IL)-1β by ac
Externí odkaz:
https://doaj.org/article/67311714292949e789a807e78b9e0188
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Metabolic fluxes are at the heart of metabolism and growth in any living system. During tuberculosis (TB) infection, the pathogenic Mycobacterium tuberculosis (Mtb) adapts its nutritional behaviour and metabolic fluxes to survive in human macrophages
Externí odkaz:
https://doaj.org/article/863abbb4f1ff48529197dc69f866ad5e
Autor:
Zaven A. Karalyan, Susanna A. Ghonyan, Davit A. Poghosyan, Lina H. Hakobyan, Hranush R. Avagyan, Aida S. Avetisyan, Liana O. Abroyan, Arpine A. Poghosyan, Sona A. Hakobyan, Gayane P. Manukyan
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 164 (2024)
Background: The African swine fever (ASF) virus (ASFV) and ASF-like viral sequences were identified in human samples and sewage as well as in different water environments. Pigs regularly experience infections by the ASFV. The considerable stability o
Externí odkaz:
https://doaj.org/article/5a07a616459d4dc79171fd8dfc027fea
Autor:
Sinem Gunalp, Derya Goksu Helvaci, Aysenur Oner, Ahmet Bursalı, Alessandra Conforte, Hüseyin Güner, Gökhan Karakülah, Eva Szegezdi, Duygu Sag
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTNF-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can either induce cell death or activate survival pathways after binding to death receptors (DRs) DR4 or DR5. TRAIL is investigated as a therapeutic agent
Externí odkaz:
https://doaj.org/article/4de8f8e86e3642108304756b87a6437c
Autor:
Amaia Garmendia Urdalleta, Mathijs Van Poll, Niamh Fahy, Janneke Witte-Bouma, Willem Van Wamel, Iulian Apachitei, Amir A. Zadpoor, Lidy E. Fratila-Apachitei, Eric Farrell
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Macrophage responses following the implantation of orthopaedic implants are essential for successful implant integration in the body, partly through intimate crosstalk with human marrow stromal cells (hMSCs) in the process of new bone formation. Addi
Externí odkaz:
https://doaj.org/article/9ee81ae85f0f42618dbc1ab93e8d4369
Autor:
Joana Wilton, Filipa Lopes de Mendonça, Isabel Pereira-Castro, Michael Tellier, Takayuki Nojima, Angela M. Costa, Jaime Freitas, Shona Murphy, Maria Jose Oliveira, Nicholas J. Proudfoot, Alexandra Moreira
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMacrophages are essential cells of the immune system that alter their inflammatory profile depending on their microenvironment. Alternative polyadenylation in the 3’UTR (3’UTR-APA) and intronic polyadenylation (IPA) are mechanisms tha
Externí odkaz:
https://doaj.org/article/03c0414266d441a4894af70fb55f5004
Akademický článek
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Autor:
Kangling Zhang, Mark L. Sowers, Ellie I. Cherryhomes, Vipul K. Singh, Abhishek Mishra, Blanca I. Restrepo, Arshad Khan, Chinnaswamy Jagannath
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophages are the preeminent phagocytic cells which control multiple infections. Tuberculosis a leading cause of death in mankind and the causative organism Mycobacterium tuberculosis (MTB) infects and persists in macrophages. Macrophages use react
Externí odkaz:
https://doaj.org/article/430127cf2afd426fafd65b8cca7fff42