Zobrazeno 1 - 10
of 309
pro vyhledávání: '"human infection model"'
Autor:
Stephen Muhi, Daniel P. O'Brien, Julia L. Marshall, Gayle Ross, Paul D.R. Johnson, Laura K. Mackay, Anand Ramakrishnan, James S. McCarthy, Marcel Doerflinger, Euzebiusz Jamrozik, Timothy P. Stinear, Joshua Osowicki
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Critical knowledge gaps have impeded progress towards reducing the global burden of disease due to Mycobacterium ulcerans, the cause of the neglected tropical disease Buruli ulcer (BU). Development of a controlled human infection model of BU has been
Externí odkaz:
https://doaj.org/article/c3b3819748b94938bdc0ba761aa200a3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The mucosal immune system is a critical first line of defense to infectious diseases, as many pathogens enter the body through mucosal surfaces, disrupting the balanced interactions between mucosal cells, secretory molecules, and microbiota in this c
Externí odkaz:
https://doaj.org/article/336083f3ce2e4e9d8154f0aff965a924
Autor:
Stephen Muhi, Daniel P. O'Brien, Julia L. Marshall, Gayle Ross, Paul D.R. Johnson, Laura K. Mackay, Anand Ramakrishnan, James S. McCarthy, Marcel Doerflinger, Euzebiusz Jamrozik, Timothy P. Stinear, Joshua Osowicki
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Critical knowledge gaps have impeded progress towards reducing the global burden of disease due to Mycobacterium ulcerans, the cause of the neglected tropical disease Buruli ulcer (BU). Development of a controlled human infection model of BU has been
Externí odkaz:
https://doaj.org/article/edc943f8fc3e49d9b390671211b87caf
Autor:
Clara Ngoliwa, Kondwani Jambo, Neema Toto, Vitumbiko S. Nkhoma, Lorensio Chimgoneko, Marc Henrion, Lumbani Makhaza, John Ndaferankhande, Stephen B. Gordon, Gift Chiwala, Gareth Lipunga, Anthony Emeritus Chirwa, Bridgette Galafa, Faith Thole, Evarista Kudowa, Morrison Peace Kamanga, Godwin Tembo, Dingase Dula, Daniela M. Ferreira, Tarsizio Chikaonda, Ndaziona Peter Kwanjo Banda, Edna Nsomba
Publikováno v:
Wellcome Open Research, Vol 9 (2024)
Background Streptococcus pneumoniae is a major cause of morbidity and mortality from respiratory tract infections, pneumonia, meningitis, and sepsis. Nasopharyngeal carriage of pneumococcus is a prerequisite for pneumococcal disease and transmission.
Externí odkaz:
https://doaj.org/article/c01b3e2b0cc342a49260484f2f7a941c
Autor:
Amy M. Jones, Todd L. Saretsky, Charlotte Panter, Jane R. Wells, Frances White, Verity Smith, Helen Kendal, Kevin Russell, Madelyn Ruggieri, Shawna R. Calhoun, Adam Gater, Justin O’Hagan, Kathryn B. Anderson, Valerie A. Paz-Soldan, Amy C. Morrison, Lisa Ware, Michelle Klick, Stephen Thomas, Morgan A. Marks
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-18 (2023)
Abstract Background Dengue is the most prevalent arboviral infection causing an estimated 50–60 million cases of febrile illness globally per year, exacting considerable disease burden. Few instruments exist to assess the patient illness experience
Externí odkaz:
https://doaj.org/article/184c2e4578e846c188f7230c30975c5c
Autor:
Jan Pieter R. Koopman, Emma L. Houlder, Jacqueline J. Janse, Miriam Casacuberta-Partal, Olivia A.C. Lamers, Jeroen C. Sijtsma, Claudia de Dood, Stan T. Hilt, Arifa Ozir-Fazalalikhan, Vincent P. Kuiper, Geert V.T. Roozen, Laura M. de Bes-Roeleveld, Yvonne C.M. Kruize, Linda J. Wammes, Hermelijn H. Smits, Lisette van Lieshout, Govert J. van Dam, Inge M. van Amerongen-Westra, Pauline Meij, Paul L.A.M. Corstjens, Simon P. Jochems, Angela van Diepen, Maria Yazdanbakhsh, Cornelis H. Hokke, Meta Roestenberg
Publikováno v:
EBioMedicine, Vol 97, Iss , Pp 104832- (2023)
Summary: Background: A controlled human infection model for schistosomiasis (CHI-S) can speed up vaccine development and provides insight into early immune responses following schistosome exposure. Recently, we established CHI-S model using single-se
Externí odkaz:
https://doaj.org/article/47a3e655db044c188dcbfa221310dd96
Akademický článek
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Autor:
James E. Meiring, Emma Smith, Peter W.S. Hill, Malick M. Gibani, Megan E. Carey, Christopher Chiu, Melita Gordon, Graham Cooke, Thomas C. Darton, Jay Hinton, Christopher Smith, Robert K.M. Choy, Blanca Perez Sepulveda
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Invasive non-typhoidal Salmonella disease (iNTS) is a major cause of morbidity and mortality globally, particularly as a cause of bloodstream infection in children and immunocompromised adults in sub-Saharan Africa. Vaccines to prevent non-typhoidal
Externí odkaz:
https://doaj.org/article/1feb40961b6541d49ab39f6dd848833b
Autor:
Kawsar R. Talaat, Chad K. Porter, Subhra Chakraborty, Brittany L. Feijoo, Jessica Brubaker, Brittany M. Adjoodani, Barbara DeNearing, Michael G. Prouty, Steven T. Poole, A. Louis Bourgeois, Madison Billingsley, David A. Sack, Susanne Eder-Lingelbach, Christian Taucher
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 727 (2024)
Controlled human infection models are important tools for the evaluation of vaccines against diseases where an appropriate correlate of protection has not been identified. Enterotoxigenic Escherichia coli (ETEC) strain LSN03-016011/A (LSN03) is an LT
Externí odkaz:
https://doaj.org/article/5f3a34f3ebdc48288a3296a738ed5782
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.