Zobrazeno 1 - 10
of 112
pro vyhledávání: '"human induced pluripotent stem cell-derived cardiomyocyte"'
Autor:
Jingbo Zhang, Junjun Li, Xiang Qu, Yuting Liu, Lifu Sun, Akima Harada, Ying Hua, Nagako Sougawa, Akiko Tabata, Li Liu, Shigeru Miyagawa
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 533-548 (2024)
Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have been widely used in therapy of ischemic heart disease. However, there are still remaining issues that limit the therapeutic efficacy, such as immune rejection and low retenti
Externí odkaz:
https://doaj.org/article/fb2d290dc6924a5588fb4b8e5ff48308
Autor:
Yuki Tatekoshi, Chunlei Chen, Jason Solomon Shapiro, Hsiang-Chun Chang, Malorie Blancard, Davi M Lyra-Leite, Paul W Burridge, Matthew Feinstein, Richard D'Aquila, Priscilla Hsue, Hossein Ardehali
Publikováno v:
eLife, Vol 13 (2024)
Heart failure with preserved ejection fraction (HFpEF) is commonly found in persons living with HIV (PLWH) even when antiretroviral therapy suppresses HIV viremia. However, studying this condition has been challenging because an appropriate animal mo
Externí odkaz:
https://doaj.org/article/d554a4e305244435abefadbdb0b10274
Publikováno v:
Health Science Reports, Vol 7, Iss 4, Pp n/a-n/a (2024)
Abstract Background and Aims Fibrotic tissue formed after myocardial infarction (MI) can be as detrimental as MI itself. However, current in vitro cardiac fibrosis models fail to recapitulate the complexities of post‐MI tissue. Moreover, although M
Externí odkaz:
https://doaj.org/article/7f7295325d194ac7b3a688044a403904
Autor:
Kirsi Penttinen, Chandra Prajapati, Disheet Shah, Dhanesh Kattipparambil Rajan, Reeja Maria Cherian, Heikki Swan, Katriina Aalto-Setälä
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Brugada syndrome is an inherited cardiac arrhythmia disorder that is mainly associated with mutations of the cardiac voltage-gated sodium channel alpha subunit 5 (SCN5A) gene. The clinical symptoms include ventricular fibrillation and an inc
Externí odkaz:
https://doaj.org/article/b8f5da083e904625801bb2828d0ea664
Autor:
Nino Chirico, Elise L. Kessler, Renée G. C. Maas, Juntao Fang, Jiabin Qin, Inge Dokter, Mark Daniels, Tomo Šarić, Klaus Neef, Jan-Willem Buikema, Zhiyong Lei, Pieter A. Doevendans, Joost P. G. Sluijter, Alain van Mil
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iPSC-CMs) do not display all hallmarks of mature primary cardiomyocytes, especially the ability to use fatty acids (FA) as an energy source, containing high mitoch
Externí odkaz:
https://doaj.org/article/f236b2a240974c269001a691fb9bb725
Akademický článek
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Autor:
Shigeru Miyagawa, Satoshi Kainuma, Takuji Kawamura, Kota Suzuki, Yoshito Ito, Hiroko Iseoka, Emiko Ito, Maki Takeda, Masao Sasai, Noriko Mochizuki-Oda, Tomomi Shimamoto, Yukako Nitta, Hiromi Dohi, Tadashi Watabe, Yasushi Sakata, Koichi Toda, Yoshiki Sawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Despite major therapeutic advances, heart failure, as a non-communicable disease, remains a life-threatening disorder, with 26 million patients worldwide, causing more deaths than cancer. Therefore, novel strategies for the treatment of heart failure
Externí odkaz:
https://doaj.org/article/d2598ef6482f44ff824c95618be2a291
Autor:
Rujia Zhong, Feng Zhang, Zhen Yang, Yingrui Li, Qiang Xu, Huan Lan, Siegfried Lang, Lukas Cyganek, Elke Burgermeister, Ibrahim El-Battrawy, Xiaobo Zhou, Ibrahim Akin, Martin Borggrefe
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCardiac dysfunction including arrhythmias appear frequently in patients with cancers, which are expected to be caused mainly by cardiotoxic effects of chemotherapy. Experimental studies investigating the effects of cancer cell secretion wit
Externí odkaz:
https://doaj.org/article/89b99264693c4a819cf61d8f72332f1b
Akademický článek
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Akademický článek
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