Zobrazeno 1 - 10
of 986
pro vyhledávání: '"human adipocytes"'
Autor:
Farah Omran, Alice M. Murphy, Awais Z. Younis, Ioannis Kyrou, Jana Vrbikova, Vojtech Hainer, Petra Sramkova, Martin Fried, Graham Ball, Gyanendra Tripathi, Sudhesh Kumar, Philip G. McTernan, Mark Christian
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Dysfunctional adipose tissue (AT) is known to contribute to the pathophysiology of metabolic disease, including type 2 diabetes mellitus (T2DM). This dysfunction may occur, in part, as a consequence of gut-derived endotoxaemia ind
Externí odkaz:
https://doaj.org/article/866329b7286347818635c4f34ca555da
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The activation of the P2X7 receptor subtype (P2X7R) has a main role in orchestrating the cellular inflammatory response in many different tissues. Obesity is characterized by dysfunctional fat deposition leading to a tissue-specific and
Externí odkaz:
https://doaj.org/article/1c1ad988f0ee4a63ad51c36a78fddb21
Autor:
Aaron Taehwan Kim, Yeonhwa Park
Publikováno v:
Current Research in Food Science, Vol 7, Iss , Pp 100646- (2023)
Trifuhalol A, a fucol-type phlorotannin, was extracted and identified from the brown algae Agarum cribrosum. The total yield and purity of trifuhalol A from A. cribrosum were 0.98% and 86%, respectively. Trifuhalol A at 22 and 44 μM inhibited lipid
Externí odkaz:
https://doaj.org/article/f1b84a5cb51e4d4ba05659170f6a7147
Autor:
Neha Mathur, Mai C. K. Severinsen, Mette E. Jensen, Lars Naver, Maren Schrölkamp, Matthew J. Laye, Matthew J. Watt, Søren Nielsen, Rikke Krogh-Madsen, Bente Klarlund Pedersen, Camilla Scheele
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Abdominal obesity associates with cardiometabolic disease and an accumulation of lipids in the visceral adipose depot, whereas lipid accumulation in the subcutaneous depot is more benign. We aimed to further investigate whether the adipogenic propert
Externí odkaz:
https://doaj.org/article/4ff6e59fafb1446b86acf06a38232bf2
Autor:
Corinna Niersmann, Karin Röhrig, Matthias Blüher, Michael Roden, Christian Herder, Maren Carstensen-Kirberg
Publikováno v:
Obesity Facts, Vol 13, Iss 2, Pp 221-236 (2020)
Objectives: To investigate the impact of omentin on the release of inflammation-related biomarkers and inflammatory pathways in primary human adipocytes. Methods: Adipocytes were treated with or without omentin (500 and 2,000 ng/mL), and the supernat
Externí odkaz:
https://doaj.org/article/f954334cb4c847c88482e73ddf589dd4
Publikováno v:
Cells, Vol 11, Iss 15, p 2282 (2022)
It is increasingly recognized that hypoxia may develop in adipose tissue as its mass expands. Adipose tissue is also the main reservoir of lipophilic pollutants, including polychlorinated biphenyls (PCBs). Both hypoxia and PCBs have been shown to alt
Externí odkaz:
https://doaj.org/article/5be754ca99ff409cbb1cdc1065c59ddc
Autor:
Jessica Latorre, Angeles Aroca, José Manuel Fernández-Real, Luis C. Romero, José María Moreno-Navarrete
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1095 (2022)
Recent studies in mice and humans demonstrated the relevance of H2S synthesising enzymes, such as CTH, CBS, and MPST, in the physiology of adipose tissue and the differentiation of preadipocyte into adipocytes. Here, our objective was to investigate
Externí odkaz:
https://doaj.org/article/8a189b21a3314fb48ac98d69e8a64af0
Autor:
Niersmann, Corinna, Röhrig, Karin, Blüher, Matthias, Roden, Michael, Herder, Christian, Carstensen-Kirberg, Maren
Objectives: To investigate the impact of omentin on the release of inflammation-related biomarkers and inflammatory pathways in primary human adipocytes. Methods: Adipocytes were treated with or without omentin (500 and 2,000 ng/mL), and the supernat
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A83650
https://ul.qucosa.de/api/qucosa%3A83650/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A83650/attachment/ATT-0/
Akademický článek
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Autor:
Max Friesen, Raymond Camahort, Youn-Kyoung Lee, Fang Xia, Robert E. Gerszten, Eugene P. Rhee, Rahul C. Deo, Chad A. Cowan
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1164-1173 (2017)
The striking rise of obesity-related metabolic disorders has focused attention on adipocytes as critical mediators of disease phenotypes. To better understand the role played by excess adipose in metabolic dysfunction it is crucial to decipher the tr
Externí odkaz:
https://doaj.org/article/c5a6d5ca9a554f4894d3f18ebcfffbac