Zobrazeno 1 - 10
of 14 382
pro vyhledávání: '"human & disease"'
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 297-327 (2024)
Background: Autophagy is an evolutionarily conserved turnover process for intracellular substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) mechanisms. In the past two decades, emerging evidence suggests that
Externí odkaz:
https://doaj.org/article/a30c373708bd4ee486bcdc1c38d6f723
Autor:
Jürgen Borlak, Yari Ciribilli, Alessandra Bisio, Saravanakumar Selvaraj, Alberto Inga, Jung-Hwa Oh, Reinhard Spanel
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-34 (2024)
Abstract Background Doxorubicin is an important anticancer drug, however, elicits dose-dependently cardiomyopathy. Given its mode of action, i.e. topoisomerase inhibition and DNA damage, we investigated genetic events associated with cardiomyopathy a
Externí odkaz:
https://doaj.org/article/e2adbab09e374e0287dee8c39f980553
Autor:
Made Yogi Krisnanda, Luh Putu Feby Sriandari, Sheila Gerhana Darmayanti, Gede Ngurah Rsi Suwardana
Publikováno v:
Jurnal Respirasi, Vol 10, Iss 3, Pp 236-242 (2024)
Introduction: Pulmonary agenesis is a rare lung disease, occurring in approximately 1 out of every 100,000 births. Most cases of pulmonary agenesis result in death during the neonatal period. Although survival in cases of pulmonary agenesis is rare,
Externí odkaz:
https://doaj.org/article/781f4aea70ea42849e1846d2ecb41a51
Publikováno v:
Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, Vol 15, Iss 2, Pp 83-87 (2024)
Introduction: Chronic rhinosinusitis (CRS) is often encountered in Indonesia. Nasal endoscopy, or nasendoscopy, is considered the gold standard for assessing the severity of CRS. However, as nasendoscopy is unavailable in Indonesia, only symptom asse
Externí odkaz:
https://doaj.org/article/85a4cc9d4dfa4e26a00d540222e9a757
Publikováno v:
Microbial Cell, Vol 11, Pp 288-311 (2024)
The role of model organisms such as yeasts in life science research is crucial. Although the baker’s yeast (Saccharomyces cerevisiae) is the most popular model among yeasts, the contribution of the fission yeasts (Schizosaccharomyces) to life scien
Externí odkaz:
https://doaj.org/article/4b29eec1ad7e460faaa6c878ce675902
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-41 (2024)
Abstract Ferroptosis, an iron-dependent form of cell death characterized by uncontrolled lipid peroxidation, is governed by molecular networks involving diverse molecules and organelles. Since its recognition as a non-apoptotic cell death pathway in
Externí odkaz:
https://doaj.org/article/c485b186ccd74859a3c47cf2701a8311
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/fdeabf3ac3db40f49bf060c8f130cec1
Publikováno v:
Medical Review, Vol 4, Iss 2, Pp 129-153 (2024)
In the field of biomedical research, organoids represent a remarkable advancement that has the potential to revolutionize our approach to studying human diseases even before clinical trials. Organoids are essentially miniature 3D models of specific o
Externí odkaz:
https://doaj.org/article/c55afd21575b4b0c8e1268f0f8d21a69
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-26 (2024)
Abstract The field of transcriptional regulation has revealed the vital role of chromatin modifiers in human diseases from the beginning of functional exploration to the process of participating in many types of disease regulatory mechanisms. Chromat
Externí odkaz:
https://doaj.org/article/8ca10f9654bd40c7a1c921e96d8cc66d
Publikováno v:
Journal of Advanced Research, Vol 58, Iss , Pp 175-191 (2024)
Background: Autophagy refers to the conserved cellular catabolic process relevant to lysosome activity and plays a vital role in maintaining the dynamic equilibrium of intracellular matter by degrading harmful and abnormally accumulated cellular comp
Externí odkaz:
https://doaj.org/article/d82398263bac4cdfa96121953ed7acd8