Zobrazeno 1 - 10
of 14 326
pro vyhledávání: '"hox"'
Autor:
Mizuki Ishizaka, Akiteru Maeno, Hidemichi Nakazawa, Renka Fujii, Sae Oikawa, Taisei Tani, Haruna Kanno, Rina Koita, Akinori Kawamura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The paralogs 9–13 Hox genes in mouse HoxA and HoxD clusters are critical for limb development. When both HoxA and HoxD clusters are deleted in mice, significant limb truncation is observed compared to the phenotypes of single and compound
Externí odkaz:
https://doaj.org/article/0558479b380c4f5c93ab00958c1cf346
Autor:
B. Madhu Krishna, Pankaj Garg, Sravani Ramisetty, Ayalur Raghu Subbalakshmi, Prakash Kulkarni, Ravi Salgia, Sharad S. Singhal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Cancer ranks as the second leading cause of mortality worldwide, prompting extensive investigations into factors contributing to its development. Among these factors, genetic variations, known as genotypic polymorphisms, have been identified
Externí odkaz:
https://doaj.org/article/0d99d8963d68446895dae769be7a8ec6
Publikováno v:
EvoDevo, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Hox genes are transcriptional regulators that elicit cell positional identity along the anterior–posterior region of the body plan across different lineages of Metazoan. Comparison of Hox gene expression across distinct species reveals the
Externí odkaz:
https://doaj.org/article/45580ee784724fefa0abb99f455d7aed
Autor:
JiaoLin Yang, JinPeng Li, SuFen Li, YuTong Yang, HuanCheng Su, HongRui Guo, Jing Lei, YaLin Wang, KaiTing Wen, Xia Li, SanYuan Zhang, Zhe Wang
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-24 (2024)
Abstract Endometrial cancer (UCEC) is one of three major malignant tumors in women. The HOX gene regulates tumor development. However, the potential roles of HOX in the expression mechanism of multiple cell types and in the development and progressio
Externí odkaz:
https://doaj.org/article/ebb78266384549799ffc3e6b8a8bf333
Autor:
Daniel J. Leite, Anna Schönauer, Grace Blakeley, Amber Harper, Helena Garcia-Castro, Luis Baudouin-Gonzalez, Ruixun Wang, Naïra Sarkis, Alexander Günther Nikola, Venkata Sai Poojitha Koka, Nathan J. Kenny, Natascha Turetzek, Matthias Pechmann, Jordi Solana, Alistair P. McGregor
Publikováno v:
EvoDevo, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Spiders are a diverse order of chelicerates that diverged from other arthropods over 500 million years ago. Research on spider embryogenesis, particularly studies using the common house spider Parasteatoda tepidariorum, has made important co
Externí odkaz:
https://doaj.org/article/19ef6a966ae741cdac50bae49383e81f
Autor:
Anna Candoni, Gabriele Coppola
Publikováno v:
Hematology Reports, Vol 16, Iss 2, Pp 244-254 (2024)
Menin inhibitors are new and promising agents currently in clinical development that target the HOX/MEIS1 transcriptional program which is critical for leukemogenesis in histone-lysine N-methyltransferase 2A-rearranged (KMT2Ar) and in NPM1-mutated (N
Externí odkaz:
https://doaj.org/article/7cc63b2b6a454a1684d46c256dd600f1
Autor:
Min Wang, Yuan Ou, Zijian Guo, Juan Li, Huilin Li, Xinyi Li, Jingyang Li, Shi Wang, Qingfeng Liu, Jing Wang, Yuqin Shu, Shaojun Liu
Publikováno v:
Reproduction and Breeding, Vol 4, Iss 1, Pp 46-54 (2024)
The production of hybrid progeny through distant hybridization holds great significance in enriching germplasm resources for fish breeding. In this study, a hybridization experiment was conducted between female KOC (Cyprinus carpio haematopterus) and
Externí odkaz:
https://doaj.org/article/64dbcd91c55f4935bb0158d55abe1719
Akademický článek
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Akademický článek
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Autor:
Ghada Salah, Manar Obada, Dina Sweed, Ibrahim Abdelkader Salama, Ashraf Khalil, Shimaa Abdelsattar
Publikováno v:
Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background Pancreatic adenocarcinoma, recognized for its aggressive behavior and frequent late-stage diagnosis, imposes significant challenges in early detection and prognosis. This study aimed to evaluate the diagnostic and prognostic poten
Externí odkaz:
https://doaj.org/article/28ee8b5faed34482baafac83d5fb5a78